Increased innate immune responses in adolescents with obesity and its relation to subclinical cardiovascular measures : an exploratory study

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dc.contributor.authorBekkering Siroon
dc.contributor.authorSaner Christoph
dc.contributor.authorNovakovic Boris
dc.contributor.authorMansell Toby
dc.contributor.authorLongmore Danielle K.
dc.contributor.authorMcCallum Zoe
dc.contributor.authorPonsonby Anne-Louise
dc.contributor.authorJuonala Markus
dc.contributor.authorNetea Mihai G.
dc.contributor.authorSabin Matthew A.
dc.contributor.authorSaffery Richard
dc.contributor.authorRiksen Niels P.
dc.contributor.authorBurgner David P.
dc.contributor.organizationfi=sisätautioppi|en=Internal Medicine|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.40502528769
dc.converis.publication-id393367653
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/393367653
dc.date.accessioned2025-08-27T23:07:14Z
dc.date.available2025-08-27T23:07:14Z
dc.description.abstract<p>Cardiometabolic risk accrues across the lifecourse and childhood and adolescence are key periods for effective prevention. Obesity is associated with inflammation in adults, but paediatric data are scarce. In a cross-sectional and longitudinal study, we investigated immune cell composition and activation in 31 adolescents with obesity (41.9% male, BMIz>2.5, 14.4y) and 22 controls with healthy weight (45.1% male, -1.5</p>
dc.identifier.eissn2589-0042
dc.identifier.olddbid203429
dc.identifier.oldhandle10024/186456
dc.identifier.urihttps://www.utupub.fi/handle/11111/35224
dc.identifier.urlhttps://doi.org/10.1016/j.isci.2024.109762
dc.identifier.urnURN:NBN:fi-fe2025082786073
dc.language.isoen
dc.okm.affiliatedauthorJuonala, Markus
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline3121 Internal medicineen_GB
dc.okm.discipline3121 Sisätauditfi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherCell Press
dc.publisher.countryUnited Statesen_GB
dc.publisher.countryYhdysvallat (USA)fi_FI
dc.publisher.country-codeUS
dc.relation.articlenumber109762
dc.relation.doi10.1016/j.isci.2024.109762
dc.relation.ispartofjournaliScience
dc.relation.issue5
dc.relation.volume27
dc.source.identifierhttps://www.utupub.fi/handle/10024/186456
dc.titleIncreased innate immune responses in adolescents with obesity and its relation to subclinical cardiovascular measures : an exploratory study
dc.year.issued2024

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