Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer

Tietueen suppeat tiedot
dc.contributor.authorHilker C.
dc.contributor.authorWindebank S.
dc.contributor.authorMeyer J.
dc.contributor.authorZuber V.
dc.contributor.authorMills I.
dc.contributor.authorAndreassen O.
dc.contributor.authorWitoelar A.
dc.contributor.authorBettella F.
dc.contributor.authorKote-Jarai Z.
dc.contributor.authorEaston D.
dc.contributor.authorEeles R.
dc.contributor.authorUrbanucci A.
dc.contributor.authorGiles G.
dc.contributor.authorMuir K.
dc.contributor.authorBenlloch S.
dc.contributor.authorAl Olama A.
dc.contributor.authorWeischer M.
dc.contributor.authorTravis R.
dc.contributor.authorNeal D.
dc.contributor.authorPharoah P.
dc.contributor.authorWiklund F.
dc.contributor.authorGronberg H.
dc.contributor.authorHaiman C.
dc.contributor.authorSchleutker J.
dc.contributor.authorMaier C.
dc.contributor.authorKibel A.
dc.contributor.authorCybulski C.
dc.contributor.authorCannon-Albright L.
dc.contributor.authorKhaw K.
dc.contributor.authorStanford J.
dc.contributor.authorBlot W.
dc.contributor.authorThibodeau S.
dc.contributor.authorPandha H.
dc.contributor.authorTeixeira M.
dc.contributor.authorHumphreys M.
dc.contributor.authorChenevix-Trench G.
dc.contributor.authorPark J.
dc.contributor.authorBrenner H.
dc.contributor.authorBatra J.
dc.contributor.authorKaneva R.
dc.contributor.authorHoulston R.
dc.contributor.authorRosenberger A.
dc.contributor.authorLandi M.
dc.contributor.authorCaporaso N.
dc.contributor.authorHan Y.
dc.contributor.authorHung R.
dc.contributor.authorBickeböller H.
dc.contributor.authorBrennan P.
dc.contributor.authorEaston D.
dc.contributor.authorMichailidou K.
dc.contributor.authorChristiani D.
dc.contributor.authorAmos C.
dc.contributor.authorWu X.
dc.contributor.authorYe Y.
dc.contributor.authorHeinrich J.
dc.contributor.authorRisch A.
dc.contributor.authorOffit K.
dc.contributor.authorDennis J.
dc.contributor.authorMcGuffog L.
dc.contributor.authorCouch F.
dc.contributor.authorBerchuck A.
dc.contributor.authorAntoniou A.
dc.contributor.authorBolla M.
dc.contributor.authorWang Q.
dc.contributor.authorTessier D.
dc.contributor.authorSimard J.
dc.contributor.authorGonzalez-Neira A.
dc.contributor.authorBenitez J.
dc.contributor.authorLuccarini C.
dc.contributor.authorDicks E.
dc.contributor.authorLee A.
dc.contributor.authorDunning A.
dc.contributor.authorCunningham J.
dc.contributor.authorNordestgaard B.
dc.contributor.authorNielsen S.
dc.contributor.authorBojesen S.
dc.contributor.authorRobidoux F.
dc.contributor.authorLaBoissière S.
dc.contributor.authorVincent D.
dc.contributor.authorBacot F.
dc.contributor.organizationfi=biolääketieteen laitos|en=Institute of Biomedicine|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.77952289591
dc.converis.publication-id28257379
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/28257379
dc.date.accessioned2022-10-28T12:39:23Z
dc.date.available2022-10-28T12:39:23Z
dc.description.abstract<h3>Conclusions</h3><p>This is the first study to evaluate the enrichment of epigenetic readers in genome-wide associations studies for SNPs within enhancers, and provides a powerful tool for enriching and prioritizing PC and BC genetic risk loci. Our study represents a proof of principle applicable to other diseases and traits that can be used to redefine molecular mechanisms of human phenotypic variation.</p>
dc.identifier.jour-issn1471-2164
dc.identifier.olddbid178008
dc.identifier.oldhandle10024/161102
dc.identifier.urihttps://www.utupub.fi/handle/11111/49845
dc.identifier.urnURN:NBN:fi-fe2021042717829
dc.language.isoen
dc.okm.affiliatedauthorSchleutker, Johanna
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline3111 Biomedicineen_GB
dc.okm.discipline3122 Cancersen_GB
dc.okm.discipline3111 Biolääketieteetfi_FI
dc.okm.discipline3122 Syöpätauditfi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherBioMed Central Ltd.
dc.relation.doi10.1186/s12864-017-3620-y
dc.relation.ispartofjournalBMC Genomics
dc.relation.issue1
dc.relation.volume18
dc.source.identifierhttps://www.utupub.fi/handle/10024/161102
dc.titleBromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer
dc.year.issued2017

Tiedostot

Näytetään 1 - 1 / 1
Name:
s12864-017-3620-y.pdf
Size:
1.24 MB
Format:
Adobe Portable Document Format
Description:
Publisher's version
Lataa

Kokoelmat

Rinnakkaistallenteet