Outcome after surgery for acute type A aortic dissection with or without primary tear resection

dc.contributor.authorUimonen Mikko
dc.contributor.authorOlsson Christian
dc.contributor.authorJeppsson Anders
dc.contributor.authorGeirsson Arnar
dc.contributor.authorChemtob Raphaelle
dc.contributor.authorKhalil Ahmad
dc.contributor.authorHjortdal Vibeke
dc.contributor.authorHansson Emma C
dc.contributor.authorNozohoor Shahab
dc.contributor.authorZindovic Igor
dc.contributor.authorGunn Jarmo
dc.contributor.authorWickbom Anders
dc.contributor.authorAhlsson Anders
dc.contributor.authorGudbjartsson Tomas
dc.contributor.authorMennander Ari
dc.contributor.organizationfi=kirurgia|en=Surgery|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.97295082107
dc.converis.publication-id68604476
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/68604476
dc.date.accessioned2022-10-28T13:39:59Z
dc.date.available2022-10-28T13:39:59Z
dc.description.abstract<p><strong>Background: </strong> The outcome in patients after surgery for acute type A aortic dissection without replacement of the part of the aorta containing the primary tear is undefined.</p><p><strong>Methods: </strong> Data of 1122 patients who underwent surgery for acute type A aortic dissection in eight Nordic centers from Jan 2005 to Dec 2014 were retrospectively analyzed. The patients with primary tear location either unfound, unknown, not confirmed or not recorded (n=243, 21.7%) were excluded from the analysis. The patients were divided into two groups according to whether the aortic reconstruction encompassed the portion of the primary tear (TR group, n=730) or not (TNR group, n=149). The restricted mean survival time ratios adjusted for patient characteristics and surgical details between the groups were calculated for all-cause mortality and aortic reoperation-free survival. The median follow-up time was 2.57 (inter-quartile range 0.53-5.30) years.</p><p><strong>Results: </strong> For the majority of the patients in the TR group, the primary tear was located in the ascending aorta (83.6%). The reconstruction encompassed both aortic root and the aortic arch in 7.4% in the TR group as compared with 0.7% in the TNR patients (P<0.001). There were no significant differences in all-cause mortality (adjusted restricted mean survival time ratio 1.01, 95% confidence interval 0.92-1.12, P=0.799) or reoperation-free survival (adjusted restricted mean survival time ratio 0.98, 95% confidence interval 0.95-1.02, P=0.436) between the TR group and TNR groups.</p><p><strong>Conclusions: </strong> Primary tear resection alo</p>
dc.format.pagerange492
dc.format.pagerange501
dc.identifier.eissn1552-6259
dc.identifier.jour-issn0003-4975
dc.identifier.olddbid183477
dc.identifier.oldhandle10024/166571
dc.identifier.urihttps://www.utupub.fi/handle/11111/30390
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0003497521018464?via%3Dihub
dc.identifier.urnURN:NBN:fi-fe2022012710901
dc.language.isoen
dc.okm.affiliatedauthorGunn, Jarmo
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline3126 Surgery, anesthesiology, intensive care, radiologyen_GB
dc.okm.discipline3126 Kirurgia, anestesiologia, tehohoito, radiologiafi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisher.countryUnited Statesen_GB
dc.publisher.countryYhdysvallat (USA)fi_FI
dc.publisher.country-codeUS
dc.publisher.placeElsevier
dc.relation.doi10.1016/j.athoracsur.2021.09.067
dc.relation.ispartofjournalAnnals of Thoracic Surgery
dc.relation.issue2
dc.relation.volume114
dc.source.identifierhttps://www.utupub.fi/handle/10024/166571
dc.titleOutcome after surgery for acute type A aortic dissection with or without primary tear resection
dc.year.issued2022

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