Viimeksi syötetyt
Aineistot 10521-10540 / 45173
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Measuring the change in functional level of children rehabilitants with cerebral palsy: a brief report
<p>To compare Gross Motor Function Measure (GMFM), Gross Motor Function Classification System (GMFCS), Functional Independence Measure (FIM®), Manual Ability Classification System (MACS), and Ashworth scale in their ability ... -
Resonance energy transfer sensitises and monitors in situ switching of LOV2-based optogenetic actuators
Engineered light-dependent switches provide uniquely powerful opportunities to investigate and control cell regulatory mechanisms. Existing tools offer high spatiotemporal resolution, reversibility and repeatability. ... -
Analyses of regulatory CD4+CD25+FOXP3+ T cells and observations from peripheral T cell subpopulation markers during the development of type 1 diabetes in children
<p>Our aim was to study whether the aberrant amount or function of regulatory T cells is related to the development of type 1 diabetes (T1D) in children. We also set out to investigate the balance of different T cell ... -
Digital Waste? Unintended Consequences of Health Information Technology
IZA Institute of Labor Economics Discussion Paper Series<div>We exploit a large-scale natural experiment – the rollout of a nationwide electronic prescribing system in Finland – to study how digitization of prescriptions affects pharmaceutical use and ... -
Carotenoid-based coloration predicts both longevity and lifetime fecundity in male birds, but testosterone disrupts signal reliability
<p>Sexual selection promotes the evolution of conspicuous animal ornaments. To evolve as</p><p>signals, these traits must reliably express the “quality” of the bearer, an indicator of individual</p><p>fitness. Direct ... -
Adenosine metabolism in the vascular system
The concept of extracellular purinergic signaling was first proposed by Geoffrey Burnstock in the early 1970s. Since then, extracellular ATP and its metabolites ADP and adenosine have attracted an enormous amount of attention ... -
How Adolescents and Parents See Their Moral Responsibilities With Regard to Adolescents Using Alcohol-A Deductive Secondary Analysis
<p><strong>Background: </strong>This study described how adolescents and the parents saw their moral responsibilities with regard to adolescents using alcohol.</p><p><strong>Methods: </strong>This was a deductive secondary ... -
Using aerial photography for identification of marine and coastal habitats under the EU's Habitats Directive
<p>1. Implementation of the E.U. Habitats Directive requires information on the distribution, abundance and area covered by the habitats listed in Annex I of the Directive. <br /><br />2. In Finland, 21 of these habitats ... -
C6 peptide enzyme immunoassay in Lyme borreliosis serology
<p>The cut-off values used in C6 peptide-based enzyme immunoassay (EIA), a widely used test in Lyme borreliosis (LB) serology, have not been thoroughly analysed. The objective of the study was to examine the performance ... -
Head trauma in sports – clinical characteristics, epidemiology and biomarkers
<p>Traumatic brain injury (TBI) is clinically divided into a spectrum of severities, with mild TBI being the least severe form and a frequent occurrence in contact sports, such as ice hockey, American football, rugby, horse ... -
Microseminoprotein-Beta Expression in Different Stages of Prostate Cancer
Microseminoprotein-beta (MSMB, MSMB) is an abundant secretory protein contributed by the prostate, and is implicated as a prostate cancer (PC) biomarker based on observations of its lower expression in cancerous cells ... -
Renal hemodynamics and fatty acid uptake: effects of obesity and weight loss
Human studies of renal hemodynamics and metabolism in obesity are insufficient. We hypothesized that renal perfusion and renal free fatty acid (FFA) uptake are higher in subjects with morbid obesity compared with lean ... -
Return to work after lumbar disc herniation surgery: an occupational cohort study
Background and purpose - Lumbar disc herniation is a common surgically treated condition in the working-age population. We assessed health-related risk factors for return to work (RTW) after excision of lumbar disc herniation. ... -
An Allosteric Receptor by Simultaneous "Casting" and "Molding" in a Dynamic Combinatorial Library
Allosteric synthetic receptors are difficult to access by design. Herein we report a dynamic combinatorial strategy towards such systems based on the simultaneous use of two different templates. Through a process of ... -
Ketamine Pharmacokinetics: A Systematic Review of the Literature, Meta-analysis, and Population Analysis
<p><strong>Background: </strong>Several models describing the pharmacokinetics of ketamine are published with differences in model structure and complexity. A systematic review of the literature was performed, as well as ... -
Extended spectrum penicillins reduce the risk of omphalocele: A population-based case-control study
<p><strong>Background: </strong>Omphalocele is a major congenital anomaly associated with significant morbidity and mortality. Regardless, the influence of maternal use of prescription drugs on the risk of omphalocele has ... -
Environmental factors affecting the distributions of the native Eurasian beaver and the invasive North American beaver in Finland
When planning conservation and reintroductions of native species and control of invasive species, it is important to understand the environmental factors affecting species distributions. Habitat suitability largely determines ... -
Cuts through the manifold of molecular H2O potential energy surfaces in liquid water at ambient conditions
<p>The fluctuating hydrogen bridge bonded network of liquid water at ambient conditions entails a varied ensemble of the underlying constituting H2O molecular moieties.This is mirrored in a manifold of the H2O molecular ...