Viimeksi syötetyt

Aineistot 14561-14580 / 46619

    • Treatment with Soluble Activin Type IIB Receptor Ameliorates Ovariectomy-Induced Bone Loss and Fat Gain in Mice 

      Kiviranta Riku; Rummukainen Petri; Ritvos Olli; Puolakkainen Tero; Savontaus Eriika; Pihala-Nieminen Vappu
      <p>Introduction<br>In postmenopausal osteoporosis, hormonal changes lead to increased bone turnover and metabolic alterations including increased fat mass and insulin resistance. Activin type IIB receptors bind several ...

    • Revisiting the Question of Extending the Limits of Protection of Pharmaceutical Patents and Data Outside the EU – The Need to Rebalance 

      Daniel Opoku Acquah
      South Centre Research Paper
      <p>The European Union (EU) has instituted internal and external measures aimed at protecting and enforcing intellectual property rights. In the area of pharmaceutical patents, the Union has also sought to protect its ...

    • Multi-wavelength characterization of the blazar S5 0716+714 during an unprecedented outburst phase 

      Gaug M; Treves A; Marscher A; Myserlis I; Troitsky I; Chatterjee A; Neustroev V; Takahashi M; Gora D; Hahn A; Steele IA; Vovk I; Agudo I; Bastieri D; Miranda JM; Vasilyev AA; Teshima M; Dorner D; Konno Y; Minev M; Kubo H; Nigro C; Font L; Carosi A; Vanzo G; Niedzwiecki A; Palacio J; Tsujimoto S; Covino S; Casadio C; Colak SM; Gallozzi S; Garcia JR; Ansoldi S; Nishijima K; Gurwel M; Acosta MV; Cumani P; Suric T; Grishina TS; Maraschi L; Guberman D; Lopez RJG; Ceribella G; Nalewajko K; Takalo L; Barrio JA; Doro M; Moretti E; Pearson TJ; Garczarczyk M; Righi C; Readhead ACS; Ramazani VF; Hadasch D; Tornikoski M; Troitskaya YV; Mannheim K; Larionov VM; Contreras JL; Longo F; Zensus JA; Babic A; Ribo M; Temnikov P; Nogues L; Carosi R; Jorstad S; Madejski G; Max-Moerbeck W; Dazzi F; Mielke K; Borman GA; Moralejo A; Maneva G; Baack D; Jermak H; Rhode W; Lien AY; Hayashida M; Molina SN; Masuda S; Reeves RA; Paredes JM; Banerjee B; Persic M; Manganaro M; Lombardi S; Kuvezdic D; Gasparrini D; Strzys M; Rosillo MN; Cortina J; Rani B; Lelas D; Ward JE; Arcaro C; Rico J; Puljak I; Godinovic N; Tavecchio F; De Lotto B; Will M; Torres-Alba N; Hose J; Bangale P; Reichardt I; Fonseca MV; Delfino M; Gonzalez JB; Einecke S; Elsaesser D; Berti A; Kraus A; Galindo D; Lindfors E; Moroni PGP; Majumdar P; Lahteenmaki A; Prester DD; Morozova DA; Bonnoli G; Sitarek J; Maggio C; Kuin NPM; Paoletti R; Rugliancich A; Satalecka K; Delgado J; Ramakrishnan V; Giammaria P; Moreno V; Di Pierro F; Mazin D; Jarvela E; Mirzoyan R; Schweizer T; Bhattacharyya W; Biland A; Hovatta T; Nagayoshi T; Ahnen ML; Nilsson K; Colin P; Dominguez A; Lott B; Hassan T; Da Vela P; Savchenko SS; Bednarek W; Larionova LV; Noda K; Prandini E; Sobczynska D; Bernardini E; Kopatskaya EN; Zaric D; Angelakis E; Saito T; Ishio K; Blanch O; Pedaletti G; Krichbaum TP; Herrera J; Thompson DJ; Peresano M; de Almeida UB; Terzic T; Paiano S; Hrupec D; De Angelis A; Martinez M; Antonelli LA; Makariev M; Colombo E; Snidaric I; Kushida J; Berse RC; Lopez M; Fidalgo D; Itoh R; Fruck C; Fernandez-Barral A; Paneque D; Ninci D; Stamerra A; Mariotti M
      Context. The BL Lac object S5 0716+714, a highly variable blazar, underwent an impressive outburst in January 2015 (Phase A), followed by minor activity in February (Phase B). The MAGIC observations were triggered by the ...

    • Risk assessment of sheep welfare at small-scale slaughter in Nordic countries, comparing with large-scale slaughter 

      Hultgren J; Atkinson S; Nordensten L; Algers B; Valtari H; Mejdell CM; Ellingsen K; Eriksson S; Hreinsson K
      Background: During the pre-slaughter period, animals experience novel environment and procedures which may cause reduced welfare and suffering. Over the last decades, the slaughter industry has restructured into fewer and ...

    • Stalinin ajan elokuvan paluu: Elokuvahistorioitsijan näkökulma 

      Lauri Piispa

    • Evolving Field of Long-term Antithrombotic Therapy After Percutaneous Coronary Intervention in Patients With Atrial Fibrillation 

      Kiviniemi Tuomas O

    • Sustainability Transitions in Baltic Sea Shipping: Exploring the Responses of Firms to Regulatory Changes 

      Johanna Yliskylä-Peuralahti; Ignė Stalmokaitė

    • Hosting the Small Island Developing States: Two Scenarios 

      Vaha Milla Emilia
      <dl><dd><div><div><div><h5></h5></div><div></div></div><p></p></div><div><a>-</a><div><div><h5></h5></div><div></div></div><p></p></div><div><a>-</a><div><div><h5></h5></div><div></div></div><p>Purpose: It has been estimated ...

    • Non-native production training with an acoustic model and orthographic or transcription cues 

      Kimmo U. Peltola; Maija S. Peltola; Henna Tamminen; Paavo Alku
      <p> The perception and production of non-native speech sounds is the key to learning a new language. The differences between the native and the target language sound systems cause learning problems, but orthographic ...

    • Catalog of Long-term Transient Sources in the First 10 yr of Fermi-LAT Data 

      Mitthumsiri W; Pei Z; Fiori A; Mirabal N; Caraveo PA; Sgro C; Maldera S; Grenier IA; Monzani ME; Torres DF; Chiaro G; Kerr M; Wood K; Latronico L; Orienti M; Germani S; Hewitt JW; Franckowiak A; Baldini L; Fukazawa Y; Digel SW; Serini D; Parkinson PMS; Bissaldi E; Cutini S; Rando R; Mizuno T; Mereu I; Razzano M; Di Lalla N; Orlando E; Pesce-Rollins M; Guiriec S; Green D; Troja E; Crnogorcevic M; Bruel P; Imazawa R; Berretta A; Moskalenko IV; Palatiello M; Gasparrini D; Lubrano P; Reimer A; Buson S; Ojha R; Funk S; Spandre G; Chen S; Yassine M; Matake H; Fleischhack H; Poon H; Gonzalez JB; Orestano PC; Raino S; Bottacini E; Manfreda A; Paneque D; Fusco P; Siskind EJ; Tajima H; Loparco F; Persic M; Liodakis I; Petrosian V; Larsson S; Mazziotta MN; Porter TA; Bellazzini R; Gargano F; Gustafsson M; Kuss M; Meyer M; de Palma F; Bastieri D; Reimer O; Longo F; Dirirsa F; Cibario N; Li J; Bonino R; Griffin S; Paliya V; Suson DJ; Negro M; Blandford RD; Bloom ED; Giordano F; Nagasawa S; Rani B; Johannesson G; Ciprini S; Horan D; Principe G; Marti-Devesa G; Cavazzuti E; Lovellette MN; Luque PD; Morselli A; Razzaque S; Kocevski D; Tosti G; Ballet J; Giroletti M; Zaharijas G; D'Ammando F; Dominguez A; Cameron RA; Spinelli P; Scotton L; Di Venere L; Racusin JL; Ciangottini D; Tak D; Giglietto N
      We present the first Fermi Large Area Telescope (LAT) catalog of long-term gamma-ray transient sources (1FLT). This comprises sources that were detected on monthly time intervals during the first decade of Fermi-LAT ...

    • Kreikan 200-vuotiaan vallankumouksen monet äänet 

      Tunturi Janne
      <p>Kreikan vallankumouksen 200-vuotisjuhlavuonna julkaistiin useita uusia aihetta käsitteleviä tutkimuksia. Keskeistä niissä on äänen antaminen aiemmin vähemmän tutkituille ryhmille kuten kreikkalaisille itselleen ja ...

    • Complex Interplay Between MAZR and Runx3 Regulates the Generation of Cytotoxic T Lymphocyte and Memory T Cells 

      Rica Ramona; Gulich Alexandra F; Tizian Caroline; Hainberger Daniela; Bergthaler Andreas; Viczenczova Csilla; Ellmeier Wilfried; Laiho Asta; Khamina Kseniya; Faux Thomas; Bock Christoph; Sakaguchi Shinya; Elo Laura L; Penz Thomas; Bosselut Remy
      The BTB zinc finger transcription factor MAZR (also known as PATZ1) controls, partially in synergy with the transcription factor Runx3, the development of CD8 lineage T cells. Here we explored the role of MAZR as well as ...

    • Developing Secondary School Students' Foreign Language Speaking Skills in the Netherlands: A Design Research Study 

      Roiha Anssi; Kerbey Ann
      <p>The aim of this design research project was to investigate possible ways of developing foreign language (i.e. English) speaking skills of secondary school students who do not readily speak English in class. It was felt ...

    • Foreword: Special Issue on: Fighting Inequalities, International Journal of Telemedicine and Clinical Practices 

      Hongxiu Li; Ágústa Pálsdóttir; Roland Trill; Reima Suomi

    • Modelling habitat suitability for occurrence of human tick-borne encephalitis (TBE) cases in Finland 

      Dub Timothée; Uusitalo Ruut; Siljander Mika; Sane Jussi; Sormunen Jani J; Vapalahti Olli; Pellikka Petri
      <p>The numbers of reported human tick-borne encephalitis (TBE) cases in Europe have increased in several endemic regions (including Finland) in recent decades, indicative of an increasing threat to public health. As such, ...

    • Nanoparticle-aided glycovariant assays to bridge biomarker performance and ctDNA results 

      Sundfeldt K; Terävä J; Kekki H; Pettersson K; Gidwani K; Soukka T
      <h3>Abstract</h3><div><p>Numerous immunoassay based cancer biomarkers established in the 1970 and 1980'ies are widely used in clinical routine. Initial expectations of biomarkers such as CEA, CA125, CA19-9, AFP to ...

    • Comparing deep belief networks with support vector machines for classifying gene expression data from complex disorders 

      Frank Emmert‐Streib; Matthias Dehmer; Johannes Smolander
      Genomics data provide great opportunities for translational research and the clinical practice, for example, for predicting disease stages. However, the classification of such data is a challenging task due to their high ...

    • Long-term blood metal ion levels and clinical outcome after Birmingham hip arthroplasty 

      Pietiläinen Sakari; Lankinen Petteri; Mäkelä Keijo T.; Venäläinen Mikko S.; Lindström Miro; Laaksonen Inari
      Background and objective: Our aim was to assess long-term metal ion level changes and clinical outcome in patients with a Birmingham hip arthroplasty. Methods: For the purpose of this study, we identified all BHR hip ...

    • Viikon seitsemän päivää 

      Häkkinen Kaisa

    • Transition to Grandparenthood and Subjective Well-Being in Older Europeans: A Within-Person Investigation Using Longitudinal Data 

      Danielsbacka M; Tanskanen AO; Jokela M; Coall DA
      The transition to grandparenthood, that is the birth of the first grandchild, is often assumed to increase the subjective well-being of older adults; however, prior studies are scarce and have provided mixed results. ...