Viimeksi syötetyt

Aineistot 30161-30180 / 54746

    • Nanotechnology-based delivery of CRISPR/Cas9 for cancer treatment 

      Xu Xiaoyu; Liu Chang; Wang Yonghui; Koivisto Oliver; Zhou Junnian; Shu Yilai; Zhang Hongbo
      <p>CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats-associated protein 9) is a potent technology for gene-editing. Owing to its high specificity and efficiency, CRISPR/Cas9 is extensity used for human ...
    • The central role of septa in the basidiomycete Schizophyllum commune hyphal morphogenesis 

      Marjatta Raudaskoski
      <p>The purpose of the present research was to observe in the filamentous basidiomycete <em>Schizophyllum commune</em>, the connection between the nuclear division and polymerization of the contractile actin ring with ...
    • Antimicrobial resistance among bacteria isolated from urinary tract infections in females in Namibia, 2016-2017 

      Haindongo Erastus H; Funtua Binta; Singu Boni; Hedimbi Marius; Kalemeera Francis; Hamman Jana; Vainio Olli; Hakanen Antti J; Vuopio Jaana
      <p><strong>Background: </strong>The emergence of antimicrobial resistance (AMR) among bacterial pathogens demands a local understanding of the epidemiological situation. This information is needed both for clinical treatment ...
    • Transcatheter and surgical aortic valve replacement in patients with bicuspid aortic valve 

      Husso A; Airaksinen J; Juvonen T; Laine M; Dahlbacka S; Virtanen M; Niemelä M; Mäkikallio T; Savontaus M; Eskola M; Raivio P; Valtola A; Biancari F
      <p><strong>Objectives: </strong>To compare the outcomes after surgical (SAVR) and transcatheter aortic valve replacement (TAVR) for severe stenosis of bicuspid aortic valve (BAV).</p><p><strong>Methods: </strong>We evaluated ...
    • Collaborative participation in aphasic word searching: comparison between significant others and speech and language therapists 

      Minna Laakso
      <p> <em>Background</em>: Searching for words is a common phenomenon in conversations of the people with aphasia. When searching for a word the speaker interrupts the emerging conversational turn with a pause, vocalisation ...
    • Dystonian patofysiologia ja hoito 

      Emma A. Honkanen; Jaana Korpela; Seppo Kaakkola; Juho Joutsa
      <p><em>Dystonia on krooninen neurologinen liikehäiriösairaus, johon liittyy lisääntyneen lihasten aktiivisuuden aiheuttamia tahdosta riippumattomia, vääntäviä tai nykiviä liikkeitä ja pysyviä virheasentoja. Oireet voivat ...
    • Impact of type 2 diabetes treated with non-insulin medication and number of diabetes-coexisting diseases on EQ-5D-5L index scores in the Finnish population 

      Kari Jalkanen; Emma Aarnio; Piia Lavikainen; Hanna-Mari Jauhonen; Hannes Enlund; Janne Martikainen
      <p>Background: Type 2 diabetes (T2D) causes significant health and economic burden. In addition to comorbidities there are also coexisting diseases linked to obesity, lifestyle and T2D. The aim of this study was to examine ...
    • Poster presentations in Translation Studies: State of the art and seven tips for improvement 

      Laura Ivaska; Ester Torres-Simón
      <p>Poster presentations have established themselves in hard and social sciences, but remain an undervalued asset in Translation Studies (TS). In this paper, we report on a survey (n=104) that we carried out to map TS ...
    • Late vertebral side effects in long-term survivors of irradiated childhood brain tumor 

      Miro-Pekka Jussila; Tiina Remes; Julia Anttonen; Arja Harila-Saari; Jaakko Niinimäki; Tytti Pokka; Päivi Koskenkorva; Anna Sutela; Sanna Toiviainen-Salo; Pekka Arikoski; Pekka Riikonen; Mikko Arola; Päivi Lähteenmäki; Kirsti Sirkiä; Heikki Rantala; Maria Suo-Palosaari; Marja Ojaniemi
      <div>Purpose: Long-term side effects of the treatments are common in survivors of irradiated pediatric brain tumors. Ionizing radiation in combination with surgery and chemotherapy during childhood may reduce vertebral ...
    • Increased Risk of ADHD at Short and Long Interpregnancy Intervals in a National Birth Cohort 

      Cheslack‐Postava Keely; Sourander Andre; Suominen Auli; Jokiranta‐Olkoniemi Elina; McKeague Ian W.; Brown Alan S.
      <p><strong>Background</strong><br>Short or long interpregnancy interval (IPI) may adversely impact conditions for foetal development. Whether attention deficit hyperactivity disorder (ADHD) is related to IPI has been largely ...
    • Graduating student nurses' and student podiatrists' wound care competence - An integrative literature review 

      Emilia Kielo; Leena Salminen; Minna Stolt
      The objective of this literature review is to describe graduating student nurses' and student podiatrists' wound care competence. This integrative literature review has been conducted with a systematic search process. ...
    • Heat and mass transfer analysis of nonlinear mixed convective hybrid nanofluid flow with multiple slip boundary conditions 

      Xia Wei-Feng; Ahmad Shafiq; Khan Muhammad Naveed; Ahmad Hijaz; Rehman Aysha; Baili Jamel; Gia Tuan Nguyen
      <p>The current study focuses on the 3D nonlinear mixed convective boundary layer flow of micropolar hybrid nanofluid in the presence microorganism and multiple slip conditions across the slendering surface. The concentration ...
    • Three Standards of Athletic Superiority 

      Mika Hämäläinen
      <p> The aim of this paper is to deepen our understanding of the inherent purpose of sports competitions. In &lsquo;On Winning and Athletic Superiority&rsquo;, Nicholas Dixon states that the central comparative purpose ...
    • Prebiotic Xylo-Oligosaccharides Ameliorate High-Fat-Diet-Induced Hepatic Steatosis in Rats 

      Sanna Lensu; Raghunath Pariyani; Elina Mäkinen; Baoru Yang; Wisam Saleem; Eveliina Munukka; Maarit Lehti; Anastasiia Driuchina; Jere Linden; Marja Tiirola; Leo Lahti; Satu Pekkala
      <p>Understanding the importance of the gut microbiota (GM) in non-alcoholic fatty liver disease (NAFLD) has raised the hope for therapeutic microbes. We have shown that high hepatic fat content associated with low abundance ...
    • Hot disc of the Swift J0243.6+6124 revealed by Insight-HXMT 

      Doroshenko V; Zhang SN; Santangelo A; Ji L; Tsygankov S; Mushtukov A; Qu LJ; Zhang S; Ge MY; Chen YP; Bu QC; Cao XL; Chang Z; Chen G; Chen L; Chen TX; Chen Y; Chen YB; Cui W; Cui WW; Deng JK; Dong YW; Du YY; Fu MX; Gao GH; Gao H; Gao M; Gu YD; Guan J; Guo CC; Han DW; Hu W; Huang Y; Huo J; Jia SM; Jiang LH; Jiang WC; Jin J; Jin YJ; Kong LD; Li B; Li CK; Li G; Li MS; Li TP; Li W; Li X; Li XB; Li XF; Li YG; Li ZJ; Li ZW; Liang XH; Liao JY; Liu CZ; Liu GQ; Liu HW; Liu SZ; Liu XJ; Liu Y; Liu YN; Lu B; Lu FJ; Lu XF; Luo T; Ma X; Meng B; Nang Y; Nie JY; Ou G; Sai N; Shang RC; Song LM; Song XY; Sun L; Tan Y; Tao L; Tuo YL; Wang GF; Wang J; Wang WS; Wang YS; Wen XY; Wu BB; Wu M; Xiao GC; Xiong SL; Xu H; Xu YP; Yang YR; Yang JW; Yang S; Yang YJ; Zhang AM; Zhang CL; Zhang CM; Zhang F; Zhang HM; Zhang J; Zhang Q; Zhang T; Zhang W; Zhang WC; Zhang WZ; Zhang Y; Zhang YF; Zhang YJ; Zhang Z; Zhang ZL; Zhao HS; Zhao JL; Zhao XF; Zheng SJ; Zhu Y; Zhu YX; Zou CL; Zhang RL; Zhang RL; Zou CL; Zhu YX; Zhu Y; Zheng SJ
      We report on analysis of observations of the bright transient X-ray pulsar (XRP) Swift J0243.6+6124 obtained during its 2017-2018 giant outburst with Insight-HXMT, NuSTAR, and Swift observatories. We focus on the discovery ...
    • The effects of augmented reality-supported instruction in tertiary-level medical education 

      Christopoulos Athanasios; Pellas Nikolaos; Kurczaba Justyna; Macredie Robert
      A significant body of the literature has documented the potential of Augmented Reality (AR) in education, but little is known about the effects of AR-supported instruction in tertiary-level Medical Education (ME). This ...
    • Distributed affective space represents multiple emotion categories across the human brain 

      Saarimäki H; Ejtehadian LF; Glerean E; Jääskeläinen IP; Vuilleumier P; Sams M; Nummenmaa L
      The functional organization of human emotion systems as well as their neuroanatomical basis and segregation in the brain remains unresolved. Here, we used pattern classification and hierarchical clustering to characterize ...
    • Interactome Networks of FOSL1 and FOSL2 in Human Th17 Cells 

      Shetty Ankitha; Bhosale Santosh D; Tripathi Subhash Kumar; Buchacher Tanja; Biradar Rahul; Rasool Omid; Moulder Robert; Galande Sanjeev; Lahesmaa Riitta
      <p> Dysregulated function of Th17 cells has implications in immunodeficiencies and autoimmune disorders. Th17 cell differentiation is orchestrated by a complex network of transcription factors, including several members ...
    • Accuracy of echocardiographic area-length method in chronic myocardial infarction: comparison with cardiac CT in pigs 

      Ballo H; Tarkia M; Haavisto M; Stark C; Strandberg M; Vahasilta T; Saunavaara V; Tolvanen T; Teras M; Hynninen VV; Savunen T; Roivainen A; Knuuti J; Saraste A
      Background: We evaluated echocardiographic area-length methods to measure left ventricle (LV) volumes and ejection fraction (EF) in parasternal short axis views in comparison with cardiac computed tomography (CT) in pigs ...