Viimeksi syötetyt

Aineistot 4281-4300 / 54761

    • Neuroimaging to monitor worsening of multiple sclerosis : advances supported by the grant for multiple sclerosis innovation 

      Oh Jiwon; Airas Laura; Harrison Daniel; Järvinen Elina; Livingston Terrie; Lanker Stefan; Malik Rayaz A.; Okuda Darin T.; Villoslada Pablo; de Vries Helga E.
      <p>Key unmet needs in multiple sclerosis (MS) include detection of early pathology, disability worsening independent of relapses, and accurate monitoring of treatment response. Collaborative approaches to address these ...

    • System-Level Dynamic Model of Redox Flow Batteries (RFBs) for Energy Losses Analysis 

      Anyanwu, Ikechukwu S.; Buzzi, Fulvio; Peljo, Pekka; Bischi, Aldo; Bertei, Antonio
      <p>This paper presents a zero-dimensional dynamic model of redox flow batteries (RFBs) for the system-level analysis of energy loss. The model is used to simulate multi-cell systems considering the effect of design and ...

    • Depression and loneliness may have a direct connection without mediating factors 

      Kraav Siiri-Liisi; Lehto Soili M.; Junttila Niina; Ruusunen Anu; Kauhanen Jussi; Hantunen Sari; Tolmunen Tommi
      <p>A Brief Report<b><br /></b></p><p><b>Purpose of the article </b><br />There is growing interest in loneliness and its various adverse effects on mental and physical health. While depression is one of the adverse health ...

    • Oikeata jatsia 

      Häkkinen Kaisa

    • Integrated geological modeling of partially exposed Precambrian bedrock surface and thickness of overlying Quaternary deposits 

      Lindqvist, Teemu; Ruuska, Eemi; Kosonen, Emilia; Hornborg, Noora; Skyttä, Pietari; Putkinen, Niko; Mansikkamäki, Juho
      <p>Bedrock surface topography and thickness of the overlying sediments are key information for numerous engineering applications. However, discrete geological structures, such as bedrock deformation zones, which cause ...

    • Smart regulations in maritime governance: Efficacy, gaps, and stakeholder perspectives 

      Olaniyi Eunice O.; Solarte-Vasquez Maria Claude; Inkinen Tommi
      <p> The paper explores maritime environmental regulations, analyzing industry perspectives and their operational execution. It critically assesses the International Maritime Organization (IMO) regulations' effectiveness ...

    • Long-Term Outcomes of Adjuvant Trastuzumab for 9 Weeks or 1 Year for ERBB2-Positive Breast Cancer: A Secondary Analysis of the SOLD Randomized Clinical Trial 

      Joensuu, H; Fraser, J; Wildiers, H; Huovinen, R; Auvinen, P; Utriainen, M; Villman, KK; Halonen, P; Granstam-Björneklett, H; Tanner, M; Sailas, L; Turpeenniemi-Hujanen, T; Yachnin. J; Huttunen, T; Neven, P; Canney, P; Harvey, VJ; Kellokumpu-Lehtinen; PL; Lindman. H
      <p><strong>Importance: </strong>The standard adjuvant treatment for patients with ERRB2-positive breast cancer is chemotherapy plus 1 year of trastuzumab. Shorter durations of trastuzumab administration improve cardiac ...

    • Suomi – talous jolla piti mennä hyvin 

      Matti Viren

    • Foodscapeista gamescapeiksi: Välipalat pelaamiskäytännöissä 

      Henna Syrjälä; Tapani N. Joelsson; Kaisa Könnölä; Harri T. Luomala Saara Lundén; Mari Sandell; Tuomas Mäkilä
      <p> </p><p>Tutkimuksessa tarkastellaan pelaajien jokapäiväistä elämää etsimällä hetkiä, gamescapeja, joissa pelaamisen käytännöt yhdistyvät välipalojen kulutuskäytäntöihin. Näin pyritään vastaamaan näkemyksiin, joiden ...

    • Validation of model chains for global tilted irradiance on East-West vertical bifacial photovoltaics at high latitudes 

      Manni Mattia; Jouttijärvi Sami; Ranta Samuli; Miettunen Kati; Lobaccaro Gabriele
      <div><p>In this paper, a methodology is introduced to identify and validate the most effective model chain to estimate solar irradiance on East-West vertical bifacial <a href="https://www.sciencedirect.com/topics/enginee ...

    • A review of Bruton's tyrosine kinase inhibitors in multiple sclerosis 

      Airas, Laura; Bermel, Robert A.; Chitnis, Tanuja; Hartung, Hans-Peter; Nakahara, Jin; Stuve, Olaf; Williams, Mitzi J.; Kieseier, Bernd C.; Wiendl, Heinz
      Bruton's tyrosine kinase (BTK) inhibitors are an emerging class of therapeutics in multiple sclerosis (MS). BTK is expressed in B-cells and myeloid cells, key progenitors of which include dendritic cells, microglia and ...

    • Distribution and prevalence of the myxozoan parasite Tetracapsuloides bryosalmonae in northernmost Europe: analysis of three salmonid species 

      Lauringson M.; Ozerov M. Y.; Lopez M.-E.; Wennevik V.; Niemelä E.; Vorontsova T. Y.; Vasemägi A.
      <p>Global climate change is altering the abundance and spread of many aquatic parasites and pathogens. Proliferative kidney disease (PKD) of salmonids caused by the myxozoan <em>Tetracapsuloides bryosalmonae</em> is one ...

    • Effects of intranasal dexmedetomidine premedication on hemodynamics, oxygenation and bleeding in patients undergoing total knee arthroplasty under spinal anesthesia - a secondary analysis of a prospective, double-blinded, randomized controlled trial (TKADEX) 

      Tiainen, Suvi-Maria; Koskinen, Atte; Mäkelä, Sanna; Laitio, Ruut; Löyttyniemi, Eliisa; Mäkelä, Keijo; Pirttikangas, Carl-Olof; Saari, Teijo I.; Uusalo, Panu
      <p><strong>Background: </strong>Dexmedetomidine is a sedative adjunct with sympatholytic properties. Despite many beneficial effects, hemodynamic effects limit its use.</p><p><strong>Methods: </strong>We performed a secondary ...

    • Comorbidity in Congenital Hypothyroidism—A Nationwide, Population-based Cohort Study 

      Danner Emmi; Jääskeläinen Jarmo; Niuro Laura; Huopio Hanna; Niinikoski Harri; Viikari Liisa; Kero Jukka; Sund Reijo
      <p><strong>Context</strong></p><p>Patients with congenital hypothyroidism (CH) are affected more often than the general population by other chronic diseases and neurological difficulties.</p><p><strong>Objective</strong></p><p>The ...

    • Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis 

      Kanoni Stavroula; Graham Sarah E.; Wang Yuxuan; Surakka Ida; Ramdas Shweta; Zhu Xiang; Clarke Shoa L.; Bhatti Konain Fatima; Vedantam Sailaja; Winkler Thomas W.; Locke Adam E.; Marouli Eirini; Zajac Greg J. M.; Wu Kuan-Han H.; Ntalla Ioanna; Hui Qin; Klarin Derek; Hilliard Austin T.; Wang Zeyuan; Xue Chao; Thorleifsson Gudmar; Helgadottir Anna; Gudbjartsson Daniel F.; Holm Hilma; Olafsson Isleifur; Hwang Mi Yeong; Han Sohee; Akiyama Masato; Sakaue Saori; Terao Chikashi; Kanai Masahiro; Zhou Wei; Brumpton Ben M.; Rasheed Humaira; Havulinna Aki S.; Veturi Yogasudha; Pacheco Jennifer Allen; Rosenthal Elisabeth A.; Lingren Todd; Feng QiPing; Kullo Iftikhar J.; Narita Akira; Takayama Jun; Martin Hilary C.; Hunt Karen A.; Trivedi Bhavi; Haessler Jeffrey; Giulianini Franco; Bradford Yuki; Miller Jason E.; Campbell Archie; Lin Kuang; Millwood Iona Y.; Rasheed Asif; Hindy George; Faul Jessica D.; Zhao Wei; Weir David R.; Turman Constance; Huang Hongyan; Graff Mariaelisa; Choudhury Ananyo; Sengupta Dhriti; Mahajan Anubha; Brown Michael R.; Zhang Weihua; Yu Ketian; Schmidt Ellen M.; Pandit Anita; Gustafsson Stefan; Yin Xianyong; Luan Jian’an; Zhao Jing-Hua; Matsuda Fumihiko; Jang Hye-Mi; Yoon Kyungheon; Medina-Gomez Carolina; Pitsillides Achilleas; Hottenga Jouke Jan; Wood Andrew R.; Ji Yingji; Gao Zishan; Haworth Simon; Yousri Noha A.; Mitchell Ruth E.; Chai Jin Fang; Aadahl Mette; Bjerregaard Anne A.; Yao Jie; Manichaikul Ani; Hwu Chii-Min; Hung Yi-Jen; Warren Helen R.; Ramirez Julia; Bork-Jensen Jette; Kårhus Line L.; Goel Anuj; Sabater-Lleal Maria; Noordam Raymond; Mauro Pala; Matteo Floris; McDaid Aaron F.; Marques-Vidal Pedro; Wielscher Matthias; Trompet Stella; Sattar Naveed; Møllehave Line T.; Munz Matthias; Zeng Lingyao; Huang Jianfeng; Yang Bin; Poveda Alaitz; Kurbasic Azra; Lamina Claudia; Forer Lukas; Scholz Markus; Galesloot Tessel E.; Bradfield Jonathan P.; Ruotsalainen Sanni E.; Daw EWarwick; Zmuda Joseph M.; Mitchell Jonathan S.; Fuchsberger Christian; Christensen Henry; Brody Jennifer A.; Vazquez-Moreno Miguel; Feitosa Mary F.; Wojczynski Mary K.; Wang Zhe; Preuss Michael H.; Mangino Massimo; Christofidou Paraskevi; Verweij Niek; Benjamins Jan W.; Engmann Jorgen; Tsao Noah L.; Verma Anurag; Slieker Roderick C.; Lo Ken Sin; Zilhao Nuno R.; Le Phuong; Kleber Marcus E.; Delgado Graciela E.; Huo Shaofeng; Ikeda Daisuke D.; Iha Hiroyuki; Yang Jian; Liu Jun; Demirkan Ayşe; Leonard Hampton L.; Marten Jonathan; Frank Mirjam; Schmidt Börge; Smyth Laura J.; Cañadas-Garre Marisa; Wang Chaolong; Nakatochi Masahiro; Wong Andrew; Hutri-Kähönen Nina; Sim Xueling; Xia Rui; Huerta-Chagoya Alicia; Fernandez-Lopez Juan Carlos; Lyssenko Valeriya; Nongmaithem Suraj S.; Bayyana Swati; Stringham Heather M.; Irvin Marguerite R.; Oldmeadow Christopher; Kim Han-Na; Ryu Seungho; Timmers Paul R. H. J.; Arbeeva Liubov; Dorajoo Rajkumar; Lange Leslie A.; Prasad Gauri; Lorés-Motta Laura; Pauper Marc; Long Jirong; Li Xiaohui; Theusch Elizabeth; Takeuchi Fumihiko; Spracklen Cassandra N.; Loukola Anu; Bollepalli Sailalitha; Warner Sophie C.; Wang Ya Xing; Wei Wen B.; Nutile Teresa; Ruggiero Daniela; Sung Yun Ju; Chen Shufeng; Liu Fangchao; Yang Jingyun; Kentistou Katherine A.; Banas Bernhard; Nardone Giuseppe Giovanni; Meidtner Karina; Bielak Lawrence F.; Smith Jennifer A.; Hebbar Prashantha; Farmaki Aliki-Eleni; Hofer Edith; Lin Maoxuan; Concas Maria Pina; Vaccargiu Simona; van der Most Peter J.; Pitkänen Niina; Cade Brian E.; van der Laan Sander W.; Chitrala Kumaraswamy Naidu; Weiss Stefan; Bentley Amy R.; Doumatey Ayo P.; Adeyemo Adebowale A.; Lee Jong Young; Petersen Eva R. B.; Nielsen Aneta A.; Choi Hyeok Sun; Nethander Maria; Freitag-Wolf Sandra; Southam Lorraine; Rayner Nigel W.; Wang Carol A.; Lin Shih-Yi; Wang Jun-Sing; Couture Christian; Lyytikäinen Leo-Pekka; Nikus Kjell; Cuellar-Partida Gabriel; Vestergaard Henrik; Hidalgo Bertha; Giannakopoulou Olga; Cai Qiuyin; Obura Morgan O.; van Setten Jessica; Li Xiaoyin; Liang Jingjing; Tang Hua; Terzikhan Natalie; Shin Jae Hun; Jackson Rebecca D.; Reiner Alexander P.; Martin Lisa Warsinger; Chen Zhengming; Li Liming; Kawaguchi Takahisa; Thiery Joachim; Bis Joshua C.; Launer Lenore J.; Li Huaixing; Nalls Mike A.; Raitakari Olli T.; Ichihara Sahoko; Wild Sarah H.; Nelson Christopher P.; Campbell Harry; Jäger Susanne; Nabika Toru; Al-Mulla Fahd; Niinikoski Harri; Braund Peter S.; Kolcic Ivana; Kovacs Peter; Giardoglou Tota; Katsuya Tomohiro; de Kleijn Dominique; de Borst Gert J.; Kim Eung Kweon; Adams Hieab H. H.; Ikram M. Arfan; Zhu Xiaofeng; Asselbergs Folkert W.; Kraaijeveld Adriaan O.; Beulens Joline W. J.; Shu Xiao-Ou; Rallidis Loukianos S.; Pedersen Oluf; Hansen Torben; Mitchell Paul; Hewitt Alex W.; Kähönen Mika; Pérusse Louis; Bouchard Claude; Tönjes Anke; Chen Yii-Der Ida; Pennell Craig E.; Mori Trevor A.; Lieb Wolfgang; Franke Andre; Ohlsson Claes; Mellström Dan; Cho Yoon Shin; Lee Hyejin; Yuan Jian-Min; Koh Woon-Puay; Rhee Sang Youl; Woo Jeong-Taek; Heid Iris M.; Stark Klaus J.; Zimmermann Martina E.; Völzke Henry; Homuth Georg; Evans Michele K.; Zonderman Alan B.; Polasek Ozren; Pasterkamp Gerard; Hoefer Imo E.; Redline Susan; Pahkala Katja; Oldehinkel Albertine J.; Snieder Harold; Biino Ginevra; Schmidt Reinhold; Schmidt Helena; Bandinelli Stefania; Dedoussis George; Thanaraj Thangavel Alphonse; Kardia Sharon L. R.; Peyser Patricia A.; Kato Norihiro; Schulze Matthias B.; Girotto Giorgia; Böger Carsten A.; Jung Bettina; Joshi Peter K.; Bennett David A.; De Jager Philip L.; Lu Xiangfeng; Mamakou Vasiliki; Brown Morris; Caulfield Mark J.; Munroe Patricia B.; Guo Xiuqing; Ciullo Marina; Jonas Jost B.; Samani Nilesh J.; Kaprio Jaakko; Pajukanta Päivi; Tusié-Luna Teresa; Aguilar-Salinas Carlos A.; Adair Linda S.; Bechayda Sonny Augustin; de Silva H. Janaka; Wickremasinghe Ananda R.; Krauss Ronald M.; Wu Jer-Yuarn; Zheng Wei; Hollander Anneke Iden; Bharadwaj Dwaipayan; Correa Adolfo; Wilson James G.; Lind Lars; Heng Chew-Kiat; Nelson Amanda E.; Golightly Yvonne M.; Wilson James F.; Penninx Brenda; Kim Hyung-Lae; Attia John; Scott Rodney J.; Rao D. C.; Arnett Donna K.; Hunt Steven C.; Walker Mark; Koistinen Heikki A.; Chandak Giriraj R.; Mercader Josep M.; Costanzo Maria C.; Jang Dongkeun; Burtt Noël P.; Villalpando Clicerio Gonzalez; Orozco Lorena; Fornage Myriam; Tai EShyong; van Dam Rob M.; Lehtimäki Terho; Chaturvedi Nish; Yokota Mitsuhiro; Liu Jianjun; Reilly Dermot F.; McKnight Amy Jayne; Kee Frank; Jöckel Karl-Heinz; McCarthy Mark I.; Palmer Colin N. A.; Vitart Veronique; Hayward Caroline; Simonsick Eleanor; van Duijn Cornelia M.; Jin Zi-Bing; Qu Jia; Hishigaki Haretsugu; Lin Xu; März Winfried; Gudnason Vilmundur; Tardif Jean-Claude; Lettre Guillaume; Hart Leen M.‘t; Elders Petra J. M.; Damrauer Scott M.; Kumari Meena; Kivimaki Mika; van der Harst Pim; Spector Tim D.; Loos Ruth J. F.; Province Michael A.; Parra Esteban J.; Cruz Miguel; Psaty Bruce M.; Brandslund Ivan; Pramstaller Peter P.; Rotimi Charles N.; Christensen Kaare; Ripatti Samuli; Widén Elisabeth; Hakonarson Hakon; Grant Struan F. A.; Kiemeney Lambertus A. L. M.; de Graaf Jacqueline; Loeffler Markus; Kronenberg Florian; Gu Dongfeng; Erdmann Jeanette; Schunkert Heribert; Franks Paul W.; Linneberg Allan; Jukema J. Wouter; Khera Amit V.; Männikkö Minna; Jarvelin Marjo-Riitta; Kutalik Zoltan; Francesco Cucca; Mook-Kanamori Dennis O.; van Dijk Ko Willems; Watkins Hugh; Strachan David P.; Grarup Niels; Sever Peter; Poulter Neil; Chuang Lee-Ming; Rotter Jerome I.; Dantoft Thomas M.; Karpe Fredrik; Neville Matt J.; Timpson Nicholas J.; Cheng Ching-Yu; Wong Tien-Yin; Khor Chiea Chuen; Li Hengtong; Sabanayagam Charumathi; Peters Annette; Gieger Christian; Hattersley Andrew T.; Pedersen Nancy L.; Magnusson Patrik K. E.; Boomsma Dorret I.; Willemsen Allegonda H. M.; Cupples LAdrienne; van Meurs Joyce B. J.; Ghanbari Mohsen; Gordon-Larsen Penny; Huang Wei; Kim Young Jin; Tabara Yasuharu; Wareham Nicholas J.; Langenberg Claudia; Zeggini Eleftheria; Kuusisto Johanna; Laakso Markku; Ingelsson Erik; Abecasis Goncalo; Chambers John C.; Kooner Jaspal S.; de Vries Paul S.; Morrison Alanna C.; Hazelhurst Scott; Ramsay Michèle; North Kari E.; Daviglus Martha; Kraft Peter; Martin Nicholas G.; Whitfield John B.; Abbas Shahid; Saleheen Danish; Walters Robin G.; Holmes Michael V.; Black Corri; Smith Blair H.; Baras Aris; Justice Anne E.; Buring Julie E.; Ridker Paul M.; Chasman Daniel I.; Kooperberg Charles; Tamiya Gen; Yamamoto Masayuki; van Heel David A.; Trembath Richard C.; Wei Wei-Qi; Jarvik Gail P.; Namjou Bahram; Hayes M. Geoffrey; Ritchie Marylyn D.; Jousilahti Pekka; Salomaa Veikko; Hveem Kristian; Åsvold Bjørn Olav; Kubo Michiaki; Kamatani Yoichiro; Okada Yukinori; Murakami Yoshinori; Kim Bong-Jo; Thorsteinsdottir Unnur; Stefansson Kari; Zhang Jifeng; Chen YEugene; Ho Yuk-Lam; Lynch Julie A.; Rader Daniel J.; Tsao Philip S.; Chang Kyong-Mi; Cho Kelly; O’Donnell Christopher J.; Gaziano John M.; Wilson Peter W. F.; Frayling Timothy M.; Hirschhorn Joel N.; Kathiresan Sekar; Mohlke Karen L.; Sun Yan V.; Morris Andrew P.; Boehnke Michael; Brown Christopher D.; Natarajan Pradeep; Deloukas Panos; Willer Cristen J.; Assimes Themistocles L.; Peloso Gina M.
      <div><p><strong>Background: </strong> Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently ...

    • Teachers’ work engagement and burnout profiles: Associations with sense of efficacy and interprofessional collaboration in school 

      Holmström Anni; Tuominen Heta; Laasanen Miia; Veermans Marjaana
      <p>This study provides new insights into the work-related well-being of teachers, defined here as engagement and burnout, by investigating their associations with the teachers’ sense of efficacy and interprofessional ...

    • Enhanced antibody responses in CD19-Cre mice 

      Cunha, Diogo M.; Hernández-Pérez, Sara; Mattila, Pieta K.
      <p> CD19-Cre is an important and widely used Cre-lox model for B cell-specific genetic manipulation in murine systems. Mice carrying one allele of CD19-Cre are, at the same time, rendered heterozygote for CD19, a crucial ...

    • Ammatillisessa aikuiskoulutuksessa riittää tutkimatonta sarkaa 

      Isopahkala-Bouret Ulpukka; Vähäsantanen Katja
      <p>Ammatilliset oppilaitokset ovat aikuisten oppimisympäristöjä siinä, missä nuorten: lähes puolet opiskelijoista on opinnot aloittaessaan yli 25-vuotiaita. Aikuisten ammatillisia opintoja on yllättävän vähän tutkittu ...

    • Association of Left Atrial Appendage Morphology and Function with Stroke and Transient Ischemic Attack in Atrial Fibrillation Patients 

      Simon Judit; Smit Jeff M; Mahdiui Mohammed El; Száraz Lili; van Rosendael Alexander R; Zsarnóczay Emese; Nagy Anikó Ilona; Gellér Lászlo; van der Geest Rob J; Bax Jeroen J; Maurovich-Horvat Pál; Merkely Béla
      We aimed to correlate left atrial appendage (LAA) structure and function with the history of stroke/transient ischemic attack (TIA) in patients with atrial fibrillation (AF). We analyzed data of 649 patients with AF who ...

    • Reference genome for the Northern bat (Eptesicus nilssonii), a most northern bat species 

      Laine Veronika N.; Pulliainen Arto T.; Lilley Thomas M.
      <p>The northern bat (<em>Eptesicus nilssonii</em>) is the most northern bat species in the world. Its distribution covers whole Eurasia, and the species is thus well adapted to different habitat types. However, recent ...