Viimeksi syötetyt
Aineistot 4321-4340 / 54730
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Hepatic Glucose Uptake During Euglycemic Hyperinsulinemia Associates With Glycemia During Oral Glucose Tolerance Test
<p><strong>Context: </strong><br></p><p>Postprandial hepatic glycogen synthesis and glycolysis are reduced in hepatic insulin resistance. However, the physiologic interpretation of the reduction in hepatic glucose uptake ... -
AXES-SDSS: Comparison of SDSS galaxy groups with all-sky X-ray extended sources
<p><strong>Context.</strong> Advances in cosmological studies require us to improve our understanding of the baryonic content of galaxy groups. The key baryonic components of groups are galaxies and hot gas, while key ... -
Anticipatory governance in government : the case of Finnish higher education
<p>In response to uncertain times, liberal democracies aspire to develop anticipatory practices that usher in changes in policies and governance. These practices include creating visions and implementing roadmaps, which ... -
Convolutional neural networks for tumor segmentation by cancer type and imaging modality: a systematic review
<p>During the last few decades, a convolutional neural network (CNN) has become a very popular deep learning technique in automatic tumor segmentation of medical images of cancer patients. However, unlike for semantic ... -
Generating interstitial water within the persisting tetrahedral H-bond network explains density increase upon compressing liquid water
<p>Despite its ubiquitous nature, the atomic structure of water in its liquid state is still controversially debated. We use a combination of X-ray Raman scattering spectroscopy in conjunction with ab initio and path ... -
Miten vihapuheeseen tulisi liberaalissa demokratiassa oikeudellisesti reagoida?
<p>Sananvapauden ja rikosoikeuden välinen suhde on ollut vuosikymmeniä osa julkista keskustelua. Perinteisesti sananvapauden rikosoikeudellinen rajoittaminen on mielletty uhaksi sananvapaudelle ja demokraattiselle ... -
Plasma N-terminal containing tau fragments (NTA-tau): a biomarker of tau deposition in Alzheimer's Disease
<p><strong>Background </strong>Novel phosphorylated-tau (p-tau) blood biomarkers (e.g., p-tau181, p-tau217 or p-tau231), are highly specific for Alzheimer's disease (AD), and can track amyloid-β (Aβ) and tau pathology. ... -
Digipalvelut luovat mahdollisuuksia - ja osaamisvaatimuksia
<p>Digipalveluja tarjotaan syöpää sairastaville eri vaiheissa hoitopolkua. Uusien palveluiden käyttöönotto edellyttää hoitotyöntekijöiltä osaamisen ajantasaistamista, mihin tarvitaan johtajien tukea.</p> -
Remote ischemic preconditioning and hypoxia-induced biomarkers in acute myocardial infarction: study on a porcine model
<p><strong>Objectives</strong>. Remote ischemic preconditioning (RIPC) mitigates acute myocardial infarction (AMI). We hypothesized that RIPC reduces the size and severity of AMI and explored molecular mechanisms behind ... -
Re-examination of successful agers with lower biological than chronological age still after a 20-year follow-up period
<p><b>Background: </b>Successful ageing is the term often used for depicting exceptional ageing but a uniform definition is lacking. The aim was to re-examine and describe the successful agers living at home at the age of ... -
Functional and structural asymmetry suggest a unifying principle for catalysis in membrane-bound pyrophosphatases
<p>Membrane-bound pyrophosphatases (M-PPases) are homodimeric primary ion pumps that couple the transport of Na+- and/or H+ across membranes to the hydrolysis of pyrophosphate. Their role in the virulence of protist pathogens ... -
Consistent pressure ulcer prevention practice: The effect on PU prevalence and PU stages, and impact on PU prevention-A quasi-experimental intervention study
This study evaluates the effect of nursing staff's renewed consistent pressure ulcer (PU) prevention practice on PU prevalence and the PU prevention implemented for residents. A quasi-experimental intervention study was ... -
Functional evidence for two distinct mechanisms of action of progesterone and selective progesterone receptor modulator on uterine leiomyomas
<p><strong>Objective: </strong>To study the specific mechanisms through which progesterone and selective progesterone receptor modulators impact the growth, synthesis, and accumulation of the extracellular matrix in uterine ... -
Phosphorylcholine is located in Aggregatibacter actinomycetemcomitans fimbrial protein Flp 1
Phosphorylcholine (ChoP) is covalently incorporated into bacterial surface structures, contributing to host mimicry and promoting adhesion to surfaces. Our aims were to determine the frequency of ChoP display among ... -
The gut microbiota contributes to the pathogenesis of anorexia nervosa in humans and mice
<p>Anorexia nervosa (AN) is an eating disorder with a high mortality. About 95% of cases are women and it has a population prevalence of about 1%, but evidence-based treatment is lacking. The pathogenesis of AN probably ... -
RUNX transcription factors are essential in maintaining epididymal epithelial differentiation
<p>Apart from the androgen receptor, transcription factors (TFs) that are required for the development and formation of the different segments of the epididymis have remained unknown. We identified TF families expressed ... -
Graphic elements in early printed grammar books
Utrecht Studies in Medieval Literacy<p> Graphic devices such as tables and diagrams and other visual strategies of organising text and information are an essential part of communication. This chapter, co-authored by Janne Skaffari and Jukka Tyrkkö, focuses ... -
Surface Modification of Mesoporous Silica Nanoparticles as a Means to Introduce Inherent Cancer-Targeting Ability in a 3D Tumor Microenvironment
<p>Mesoporous silica nanoparticles (MSNs) have emerged as promising drug carriers that can facilitate targeted anticancer drug delivery, but efficiency studies relying on active targeting mechanisms remain elusive. This ... -
Female oxidative status in relation to calcium availability, metal pollution and offspring development in a wild passerine
Both Ca deficiency and metal exposure may affect physiological and nutritional condition of breeding females altering their ability to deposit essential resources (e.g. Ca, antioxidants) into the eggs. This effect of the ...
