Viimeksi syötetyt

Aineistot 641-660 / 58047

    • Surgical stage in the era of molecular profiling of endometrial cancer 

      Kasius J.C.; Kildal W.; Vrede S.W.; Askautrud H.A.; Pradhan M.; van Altena A.M.; Tobin K.-A.R.; Knoll K.; Reijnen C.; Reimann S.; Dackus G.; Vlatkovic L.; Huvila J.; Steinlechner M.; Tubita V.; Gil-Moreno A.; Snijders M.P.L.M.; Vos M.C.; Hveem T.S.; Asberger J.; Zeimet A.G.; Matias-Guiu X.; Lindemann K.; Weinberger V.; Visser N.C.M.; Kristensen G.B.; Amant F.; Pijnenborg J.M.A.; Kleppe A.
      <p>Introduction Molecular classification has reshaped risk stratification in endometrial cancer (EC), yet the relevance of tumor spread within molecular subgroups has not been reported so far. Material and methods This ...

    • Does ChatGPT Ignore Article Retractions and Other Reliability Concerns? 

      Thelwall, Mike; Lehtisaari, Marianna; Katsirea, Irini; Holmberg, Kim; Zheng, Er‐Te
      Large language models (LLMs) like ChatGPT seem to be increasingly used for information seeking and analysis, including to support academic literature reviews. To test whether the results might sometimes include retracted ...

    • Lung cancer screening in Finland: a prospective randomized trial 

      Wichmann, Viktor; Iivanainen, Sanna; Mattila, Lauri; Kokkonen, Veli-Pekka; Jartti, Airi; Kurtti, Antti; Kaarteenaho, Riitta; Andersen, Heidi; Jekunen, Antti; Vasankari, Tuula; Koivunen, Jussi
      <p><strong>Background: </strong>Early detection of lung cancer with low-dose computed tomography (LDCT) screening can shift diagnoses to early-stage disease and improve survival. However, LDCT has several challenges such ...

    • On resource consumption of machine learning in communications network security 

      Hoque, Md Muzammal; Ahmad, Ijaz; Suomalainen, Jani; Dini, Paolo; Tahir, Mohammad
      As the complexity of communication networks continues to increase, driven by a diverse array of devices, services and applications, the adoption of Machine Learning (ML) has seen a significant rise to address various ...

    • The ambiguous AT2022rze: changing-look AGN mimicking a supernova in a merging galaxy system 

      Pessi, Priscila; Lunnan, R.; Sollerman, Jesper; Yan, L.; Le Reste, A.; Yao, Y.; Nordblom, S.; Sharma, Y.; Gilfanov, M.; Sunyaev, R.; Schulze, S.; Johansson, J.; Gangopadhyay, A.; Fremling, C.; Tristram, K.; Hayes, Matthew; Fransson, C.; Hu, Yan; Brennan, S. J.; Rose, S.; De, K.; Hinds, K-Ryan; Liu, Chang; Miller, Adam; Qin, Yu-Jing; Charalampopoulos, P.; Gkini, A.; Graham, Matthew; Gutiérrez, Claudia; Mattila, Seppo; Nagao, Takashi; Perez-Fournon, I; Poidevin, F.; Bloom, J. S.; Brugger, J.; Chen, T. X.; Kasliwal, Mansi; Masci, F. J.; Purdum, J. N.
      <p>AT2022rze is a luminous, ambiguous transient located south-east of the geometric centre of its host galaxy at redshift z = 0 . 08. The host appears to be formed by a merging galaxy system. The observed characteristics ...

    • A tephrostratigraphic investigation of the continuously varved Holocene Boreal lake Nautajärvi, Finland, provides precise age estimate for Lairg A/Hekla 5 eruption 

      Carter‐Champion, Alice; Flowers, Katy; Ojala, Antti E.K.; Blockley, Simon; Lincoln, Paul; Zhang, Shuang; Manning, Christina; Puertas, Celia Martin
      Numerous cryptotephra layers originating from Icelandic volcanoes and further afield have reached Northern Europe during the Holocene. Refining the precise timing and the relative frequency of local and distal eruptions ...

    • Tongue immune compartment analysis reveals spatial macrophage heterogeneity 

      Lyras Ekaterini Maria; Zimmermann Karin; Wagner Lisa Katharina; Doerr Dorothea; Klose Christoph S; Fischer Cornelius; Jung Steffen; Yona Simon; Hovav Avi-Hai; Stenzel Werner; Dommerich Steffen; Conrad Thomas; Leutz Achim; Mildner Alexander
      The tongue is a unique muscular organ situated in the oral cavity where it is involved in taste sensation, mastication, and articulation. As a barrier organ, which is constantly exposed to environmental pathogens, the ...

    • Connected in freedom? Reconstructing a foundational value in EU and US foreign policy discourses 

      Ville Sinkkonen; Henri Vogt
      <div>The ideal of freedom has historically instituted the Transatlantic Community of Val-</div><div>ues spanning the USA and Europe. Given the framework of liberal crises that cur-</div><div>rently dominates Western mental ...

    • Hitaita muutoksia kirjallisen klassikon maineessa 

      Kokko, Laura
      <p>Tutkin kirjailija Volter Kilven (1874–1939) vastaanottoa suomalaisessa sanoma- ja aikakauslehdistössä vuosina 1900–2019 hyödyntäen lähi- ja etäluvun metodeja digitoidussa aineistossa. Esitän, että Kilven vastaanotto ...

    • sFlt-1 Impairs Neurite Growth and Neuronal Differentiation in SH-SY5Y Cells and Human Neurons 

      Barron Aaron; Barrett Lauren; Tuulari Jetro; Karlsson Linnea; Karlsson Hasse; McCarthy Cathal M; O'Keeffe Gerard W
      Pre-eclampsia (PE) is a hypertensive disorder of pregnancy which is associated with increased risk of neurodevelopmental disorders in exposed offspring. The pathophysiological mechanisms mediating this relationship are ...

    • Outlining startup culture as a global form 

      Koskinen Henri
      Startup entrepreneurship, understood as innovative venture creation and development, has gained a strong momentum under current capitalism, and startup cultures are being developed all over the globe. In this article, I ...

    • Breakpoints in Iterative Development and Interdisciplinary Collaboration of AI-Driven Automated Assessment 

      Huang, Xiaoshan; Chang, Li-Hsin; Veermans, Koen; Ginter, Filip
      <p>The rise of AI in education has led to significant advancements, promoting automated grading to reduce educator workload and to enhance pedagogy. However, its integration raises complex pedagogical, ethical, and technical ...

    • Higher initial levothyroxine doses and very early treatment start may lead to better cognitive outcomes in children with congenital hypothyroidism 

      Danner, Emmi; Niuro, Laura; Lapinoja, Sonja; Huopio, Hanna; Viikari, Liisa A.; Kero, Jukka; Jääskeläinen, Jarmo; Niinikoski, Harri
      <h3>Aim</h3><p>This study aimed to assess the cognitive development of individuals with congenital hypothyroidism.</p><h3>Methods</h3><p>Using hospital records, we identified 180 patients with congenital hypothyroidism ...

    • Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine 

      Andersen P.I.; Krpina K.; Ianevski A.; Shtaida N.; Jo E.; Yang J.; Koit S.; Tenson T.; Hukkanen V.; Anthonsen M.W.; Bjoras M.; Evander M.; Windisch M.P.; Zusinaite E.; Kainov D.E.
      Viruses are the major causes of acute and chronic infectious diseases in the world. According to the World Health Organization, there is an urgent need for better control of viral diseases. Repurposing existing antiviral ...

    • A 150-Year Debate over Surnames vs. Patronymics in Iceland 

      Willson Kendra
      <p>Iceland stands out in today’s Europe due to the fact that most Icelanders use patronymics rather than surnames. However, a small percentage of Icelanders do have surnames inherited in a fixed form. The first surnames ...

    • Both lean and fat body mass associate with blood pressure 

      Korhonen Päivi E.; Mikkola Tuija; Kautiainen Hannu; Eriksson Johan G.
      <p>High body mass index (BMI) is known to be associated with elevated blood pressure (BP). The present study aims to determine the relative importance of the two components of BMI, fat mass and lean body mass index, on BP ...

    • Cognitively healthy APOE4/4 carriers show white matter impairment associated with serum NfL and amyloid-PET 

      Tato-Fernández Claudia; Ekblad Laura L.; Pietilä Elina; Saunavaara Virva; Helin Semi; Parkkola Riitta; Zetterberg Henrik; Blennow Kaj; Rinne Juha O.; Snellman Anniina
      Except for aging, carrying the APOE ε4 allele (APOE4) is the most important risk factor for sporadic Alzheimer's disease. APOE4 carriers may have reduced capacity to recycle lipids, resulting in white matter microstructural ...

    • Fonetiikan ääntämiskurssin vaikutus vieraskielisen puheen piirteiden havaitsemiseen fonetiikan ja logopedian yliopisto-opiskelijoilla 

      Haapanen, Katja; Saloranta, Antti; Peltola, Kimmo U.; Tamminen, Henna; Peltola, Maija S.
      <div>Tutkimuksessa selvitettiin, kuinka fonetiikan ääntämiskurssi ja koulutussuuntaus vaikuttavat suomenkielisten yliopisto-opiskelijoiden kykyyn havaita ja nimetä khoekhoegowabinkielisen puheen piirteitä. Tutkimukseen ...

    • Model checking for distributed reaction systems with temporal-epistemic properties 

      Meski, Artur; Koutny, Maciej; Mikulski, Łukasz; Petre, Ion; Penczek, Wojciech; Piatkowski, Marcin
      <p>Reaction systems are a model of computation inspired by the biochemistry exhibited by living cells. This paper introduces the notion of agency as an extension to the reaction systems formalism, leading to distributed ...

    • Improved Localization of Insulinomas Using 68Ga-NODAGA-Exendin-4 PET/CT 

      Boss, M; Eriksson, O; Mikkola, K; Eek, A; Brom, M; Buitinga, M; Brouwers, AH; Velikyan, I; Waser, B; Kauhanen, S; Solin, O; Marciniak, C; Eriksson, B; Reubi, JC; Aveline, C; Wild, D; Pattou, F; Talbot, JN; Hofland, J; Sundin, A; Nuutila, P; Hermans, J; Gotthardt, M
      <p>Precise anatomic localization of insulinomas is crucial for surgical treatment. Current routine noninvasive imaging techniques, including CT, MRI, and <sup>68</sup>Ga-DOTA-somatostatin analog (DOTA-SSA) PET/CT, have ...