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Outcomes of kidney transplantation in patients with lysinuric protein intolerance
<p><strong>Background</strong><br></p><p>Lysinuric protein intolerance (LPI) is a metabolic disorder that leads to dysfunctional intestinal absorption and kidney clearance of cationic amino acids. Chronic kidney disease ... -
Smart IoT-based Solutions for Neonatal Sleep Stratification: Single-Dual Channel EEG, AdaptiSelect, Multview Fusion, & Rotational Ensemble Stacking
<p>A timely diagnosis and treatment of sleep disorders in neonates during their first week of life is crucial. Current methods for staging neonatal sleep rely heavily on multiple electroencephalography (EEG) channels. These ... -
What do we talk about when we talk about queer death?2/ LGBTQ+ necropolitics
<p>This is part 2 of 6 of the dossier<em> What do we talk about when we talk about queer death?</em>, edited by M. Petricola. The contributions collected in this article sit at the crossroads between thanatology, gender ... -
SIR+ models : accounting for interaction-dependent disease susceptibility in the planning of public health interventions
Avoiding physical contact is regarded as one of the safest and most advisable strategies to follow to reduce pathogen spread. The flip side of this approach is that a lack of social interactions may negatively affect other ... -
Targeted and Untargeted Amine Metabolite Quantitation in Single Cells with Isobaric Multiplexing
<p>We developed a single cell amine analysis approach utilizing isobarically multiplexed samples of 6 individual cells along with analyte abundant carrier. This methodology was applied for absolute quantitation of amino ... -
TSPO-Detectable Chronic Active Lesions Predict Disease Progression in Multiple Sclerosis
<p><strong>Background and objectives: </strong>In the multiple sclerosis (MS) brain, chronic active lesions can be detected using MRI- and PET-based methods. In this study, we investigated whether the frequency of ... -
International Master’s Degree Students’ Experiences of Support at a Finnish University
<p>This phenomenographicstudy explores international master’s degree students’ ways of experiencing support in Finnish higher education. The study draws on Schlossberg’s Transition Model and the Culturally Engaging Campus ... -
Energetic seed particles in self-consistent particle acceleration modeling at interplanetary shock waves
<p><em>Aims.</em> The study investigates the relevance of the seed particle population in the results of particle acceleration in interplanetary shock waves, when wave–particle interactions are treated self-consistently. ... -
Towards Transparency in Law (And in the Meanwhile, More Mediation)
<p> In this article, I address the problem that no matter how well a law or contract is dra ed it cannot foresee and take into account all the possible contexts in which it will be utilised. Law is always relatively ... -
Red pigments in autumn leaves of Norway maple do not offer significant photoprotection but coincide with stress symptoms
The reasons behind autumn colors, a striking manifestation of anthocyanin synthesis in plants, are poorly understood. Usually, not all leaves of an anthocyanic plant turn red or only a part of the leaf blade turns red. In ... -
Continent‐Wide Drivers of Spatial Synchrony in Breeding Demographic Structure Across Wild Great Tit Populations
Variation in age structure influences population dynamics, yet we have limited understanding of the spatial scale at which its fluctuations are synchronised between populations. Using 32 great tit populations, spanning 4° ... -
Horizontal Transition of Expertise
Expert performance in a domain is often defined as maximal adaptation to stable task constraints. This definition is useful when analysing the vertical transition when novices become experts. However, many workplaces undergo ... -
Decadent New Woman’s Ironic Subversions: L. Onerva’s Multi-layered Irony
<p>The decadent New Woman novel <i>Mirdja </i>(1908) by the Finnish writer L. Onerva (Hilja Onerva Lehtinen, 1882–1972) is permeated by irony. From the point of view of the eponymous heroine, the conservative bourgeois ... -
Euclid preparation LXI. Cosmic Dawn Survey: ‘Pre-launch’ multiwavelength catalogues for Euclid Deep Field North and Euclid Deep Field Fornax
The Cosmic Dawn Survey (DAWN survey) provides multiwavelength (UV/optical to mid-IR) data across the combined 59 deg2 of the Euclid Deep and Auxiliary fields (EDFs and EAFs). In this work, the first public data release ... -
Pilot scale hydrodynamic cavitation and hot-water extraction of Norway spruce bark yield antimicrobial and polyphenol-rich fractions
<p>Norway spruce (Picea abies [L.] Karst) tree bark contains high concentrations of polyphenolic compounds with antibacterial, antioxidant, and antiviral properties. While laboratory-scale extraction studies are relatively ... -
Prioritising National Competitiveness over Support for Democracy? Finnish Media Policy in the 21st Century
<p>Ever since the launch of the World Press Freedom Index almost 20 years ago, Finland has always been among the top fi ve countries of that index. According to the annual Reuters Digital News reports, Finnish people also ... -
Protocol to study early lung developmental branching in mouse embryos using explant culture
<p>Mouse lung branching morphogenesis creates epithelial tree structures required for respiration. Here, we present a protocol for studying mouse lung developmental branching using lung explant cultures. We describe steps ... -
The SV40 virus enhancer functions as a somatic hypermutation-targeting element with potential tumorigenic activity
Simian virus 40 (SV40) is a monkey virus with tumorigenic potential in rodents and is associated with several types of human cancers, including lymphomas. A related Merkel cell polyomavirus causes carcinoma in humans by ... -
The supramammillary nucleus controls anxiety-like behavior; key role of GLP-1R
Anxiety disorders are among the most prevalent categories of mental illnesses. The gut-brain axis, along with gastrointestinally-derived neuropeptides, like glucagon-like peptide-1 (GLP-1), are emerging as potential key ... -
Association of workplace violence and bullying with later suicide risk: a multicohort study and meta-analysis of published data
<p><strong>Background</strong><br></p><p>Workplace offensive behaviours, such as violence and bullying, have been linked to psychological symptoms, but their potential impact on suicide risk remains unclear. We aimed to ...