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Aineistot 8921-8940 / 54761
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A guide to heat shock factors as multifunctional transcriptional regulators
<div><p>The heat shock factors (HSFs) form a family of transcription factors, which are evolutionarily conserved in eukaryotes. They are best known as transcriptional regulators of molecular chaperone genes, including those ... -
Hepatic glucose production rises with the histological severity of metabolic dysfunction-associated steatohepatitis
<p>Metabolic dysfunction-associated steatotic liver disease (MASLD) and steatohepatitis (MASH) are associated with a high prevalence of type 2 diabetes (T2D). Individuals with MASLD exhibit insulin resistance (IR) and ... -
Social media contact with family members and happiness in younger and older adults
<p>Prior literature suggests that social media may increase older adults' well-being because they use social media to communicate with close social ties, such as family members. Despite this potential being recognized and ... -
Development of Real-Time Surveillance for Serious Adverse Events in a Pragmatic Clinical Trial Using National Registers in Finland
<p>Purpose: We developed a hybrid safety surveillance approach for a large, pragmatic clinical trial of a high-dose quadrivalent influenza vaccine (QIV-HD), using both active and passive data collection methods. Here, we ... -
Disk reflection and energetics from the accreting millisecond pulsar SRGA J144459.2−604207
<p><em>Context.</em> Accreting millisecond pulsars (AMSPs) are excellent laboratories to study reflection spectra and their features as emission is reflected off an accretion disk truncated by a rapidly rotating magnetosphere ... -
Selvitys saattohoidon ajalta läheiselle maksettavasta etuudesta: Selvityshenkilö Seppo Koskisen loppuraportti
Sosiaali- ja terveysministeriön raportteja ja muistioita<p>Sosiaali- ja terveysministeriö kutsui työoikeuden emeritusprofessori Seppo Koskisen selvittämään saattohoidon ajalta läheiselle maksettavan etuuden tarvetta ja sisältöä. Lisäksi selvityshenkilön tuli selvittää, millaisia ... -
The International Climate Psychology Collaboration: Climate change-related data collected from 63 countries
<p>Climate change is currently one of humanity's greatest threats. To help scholars understand the psychology of climate change, we conducted an online quasi-experimental survey on 59,508 participants from 63 countries ... -
Green dreams are made of this: Futures consciousness and proenvironmental engagement
Futures consciousness (FC) refers to the capacity to understand, anticipate and prepare for the future. As a form of future orientation, it encompasses five interrelated dimensions of time perspective, agency beliefs, ... -
Contaminants of emerging concern in an endangered population of common eiders (Somateria mollissima) in the Baltic Sea
<p>Contaminants of emerging concern (CECs) are ubiquitous in aquatic environments and pose a range of biological effects including endocrine disruption. Yet, knowledge of their occurrence in wildlife including seabirds ... -
Effects of fear on donations to climate change mitigation
<p> Despite 70 years of research, there is no consensus about the effects of threat messages on behavior, partly because of publication bias. The lack of consensus concerns situations such as climate change where people ... -
Properties of Cosmic-Ray Sulfur and Determination of the Composition of Primary Cosmic-Ray Carbon, Neon, Magnesium, and Sulfur: Ten-Year Results from the Alpha Magnetic Spectrometer
We report the properties of primary cosmic-ray sulfur (S) in the rigidity range 2.15 GV to 3.0 TV based on 0.38 x 106 sulfur nuclei collected by the Alpha Magnetic Spectrometer experiment (AMS). We observed that above 90 ... -
Why is ethics important in history education? A dialogue between the various ways of understanding the relationship between ethics and historical consciousness
<p>In light of current tendencies, where appreciating plurality and uphold everyone’s equal value is being questioned from different directions, there is arguably a need to revive the ethical dimension of history education ... -
FoxO1-zDHHC4-CD36 S-Acylation Axis Drives Metabolic Dysfunction in Diabetes
<p><b>BACKGROUND:</b> The fatty acid (FA) transporter CD36 (FA translocase/cluster of differentiation 36) is the gatekeeper of cardiac FA metabolism. Preferential localisation of CD36 to the sarcolemma is one of the ... -
The feeding of heather (Calluna vulgaris) to Teladorsagia circumcincta infected lambs reduces parasitism but can detrimentally impact performance
Gastrointestinal nematode (GIN) infections impact small ruminant health, welfare, and production across farming systems. Rising anthelmintic resistance and regulation of synthetic drug use in organic farming is driving ... -
Ash Ra Tempel, Manuel Göttsching, and Klaus Schulze
Cambridge Companions to Music<p>This chapter discusses the work of Manuel Göttsching and Klaus Schulze. Both were founding members of Ash Ra Tempel, a psychedelic rock band active in 1970–75. Their self-titled debut album, released in 1971, is recognised ... -
Alternative Copper-Based Single-Atom Nanozyme with Superior Multienzyme Activities and NIR-II Responsiveness to Fight against Deep Tissue Infections
Nanozymes are considered to represent a new era of antibacterial agents, while their antibacterial efficiency is limited by the increasing tissue depth of infection. To address this issue, here, we report a copper and silk ... -
Ghosts of weather past? Impact of past and present weather-related factors on the seasonal questing activity of Ixodes ricinus nymphs in southwestern Finland
<h3>Background</h3><p>Hard ticks are responsible for spreading several zoonotic infections globally. Of the main vector species in Europe, <em>Ixodes ricinus</em>, nymphal ticks cause the largest number of disease cases. ... -
Osteosarcopenia in Finland: prevalence and associated factors
<p><b>Summary</b></p><p>This cross-sectional study investigated osteosarcopenia prevalence and its correlates among 2142 adults aged 55 and older in Finland. Findings show 3.9% had osteosarcopenia, while 13.8% and 11.1% ... -
Linear optical properties of organic microcavity polaritons with non-Markovian quantum state diffusion
Hybridisation of the cavity modes and the excitons to polariton states together with the coupling to the vibrational modes determine the linear optical properties of organic semiconductors in microcavities. In this article ...