Hae

Overweight or obesity, along with type 2 diabetes mellitus, is one of the major causes of cardiovascular morbidity and mortality. In the heart, fat is deposited inside – myocardial triglyceride content, and outside the ...

While many folate-receptor (FR) targeting radiotracers have been studied for imaging cancers, there is a need for tracers that target inflammation for diagnostic and monitoring purposes. Two diseases in which inflammation ...

Modeling and analysis of positron emission tomography (PET) imaging data requires the critical information of the input function of the radioligand used. In PET imaging of the brain, the ‘gold standard’ for acquiring input ...

Alzheimer’s disease (AD) is the most common cause of dementia and a major public health issue resulting in decreased life expectancy of patients and high societal cost. Medical treatment of AD is palliative in nature as ...

Introduction: Ischemia is defined as the restriction of blood flow to a body organ, such as the heart, resulting in a cutback in oxygen supply. Myocardial ischemia is characterized by an imbalance between myocardial oxygen ...

B lymphocytes (B cells) are an important part of the adaptive immune system. Recognition of surface presented antigen, typically on antigen presenting cell (APC), by the B cell receptor (BCR) triggers BCR signaling cascades ...

Notch signaling is actively involved in cell differentiation, proliferation, and apoptosis, and plays a significant role in tumor growth and prognosis of head and neck squamous cell carcinoma (HNSCC). Altered NOTCH expression ...

Positron Emission Tomography (PET) using ¹⁸F-FDG is playing a vital role in the diagnosis and treatment planning of cancer. However, the most widely used radiotracer, ¹⁸F-FDG, is not specific for ...

Obesity and physical inactivity are major public health issues in the population of the western countries. These conditions increase the risk for the development of insulin resistance and type 2 diabetes mellitus and lead ...

Keratins are part of a filamentous structures forming the cytoskeleton. Keratins provide structural support and are involved in several cell processes. Keratins are known to affect mitochondrial function in the liver but ...