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Aineistot 11-20 / 49
Effects of parental co-exposure to heat wave and copper on zebrafish (Danio rerio) offspring thermal tolerance
(2022-06-06)
Climate change driven intensification of heat waves and increased occurrence of toxins in the aquatic environments pose a challenge for ectotherms, such as fish. Changes in the environment not only can shape the individual ...
Roundup®-kasvinsuojeluaineen vaikutus japaninviiriäisen (Coturnix japonica) fysiologiaan
(2022-03-28)
Glyfosaattipohjaiset kasvinsuojeluaineet ovat maailman käytetyimpiä kasvinsuojeluaineita. Glyfosaatti häiritsee kasvien kasvua estämällä kasvien biokemiallisen aineenvaihduntareitin, nk. sikimaattireitin toimintaa. Eläimiltä ...
Maternal Effects of Exercise Training on the Critical Thermal tolerance, Critical Swimming speed, and response to a Heatwave simulation in the juvenile brown trout (Salmo trutta)
(2022-06-21)
Heatwaves cause a notable threat to the ectothermic animals whose body temperature
depends entirely on the ambient temperature. Prolonged high temperatures negatively affect
fish physiology, as they may cause internal ...
Transgenerational effects of crude oil and heat shock on the mortality and oxygen consumption rate of Daphnia magna
(2022-07-26)
Baltic Sea is a compact area with heavy shipping activity, and since around 160 million metric tons of oil are transported annually, the risk of a major oil tanker spill is ever-present. Since climate change will raise sea ...
Evaluating computational tools for analysis of ATAC-seq data and transcription factor footprinting.
(2022-01-03)
Assay for Transposase Accessible Chromatin combined with high-throughput sequencing (ATAC-seq) is a relatively new method for inspecting the accessibility of chromatin. ATAC-seq data can be used for discovering footprints ...
Single cell RNA-seq analysis of lymphocytes from Borrelia burgdorferi infected mice
(2022-01-17)
Lyme borreliosis is a disease caused by Borrelia burgdorferi sensu lato bacteria. The symptoms of disseminated Lyme borreliosis can be nonspecific, and there is a need for specific laboratory tests. Currently, the laboratory ...
Äidin raskaudenaikaisen psykologisen stressin yhteys istukan ja napaveren glukokortikoidireseptoria koodaavan geenin DNA-metylaatioon
(2022-04-04)
Raskauden aikana n. 4–20 % naisista on havaittu kärsivän psykologisesta stressistä ja masennusoireista, jotka syntyvät erilaisten haasteiden kohtaamisesta raskauden aikana. Raskaudenaikaiset masennusoireet saattavat vaikuttaa ...
A genome-wide association study of CYP1A2 activity using tizanidine and caffeine as probe drugs
(2022-01-13)
Cytochrome P450 (CYP) enzymes are the major drug metabolizing enzyme group. The highest level of CYPs is expressed in the liver, and the human cytochrome P450 (CYP) 1A2 is one of the major CYPs playing an important role ...
Delivery of Cas9/sgRNA system using functionalized mesoporous silica nanoparticle system
(2020-09-03)
CRISPR/Cas9 has become an attractive tool for performing genomic editing due to its versatility and efficiency. However, one of the major challenges in CRISPR/Cas9-based genome editing is the active delivery to the specific ...
Automatisoidut havainnointimenetelmät vaelluskalatutkimuksessa
(2020-02-28)
Suomen suurimpia vaelluskalajokia padottiin toisen maailmansodan jälkeen vesivoiman tuotantoon, mikä yhdessä muun muassa jokien perkausten kanssa edesauttoi vaelluskalakantojen ajautumista huonoon tilaan. Esimerkiksi ...