Hae
Aineistot 11-18 / 18
Design of an EnLite PCR assay for the Detection of Congenital Cytomegalovirus
(2020-02-27)
Congenital cytomegalovirus (CCMV) infection is a major cause of childhood disabilities. Human cytomegalovirus (HCMV) infection is mostly asymptomatic and the sequelae can form months or years later. These include sensorineural ...
New set of biorelevant media for better prediction of in vivo performance of poorly water-soluble compounds
(2020-03-10)
In the development of new oral drug compounds, poorly water-soluble compounds are a challenge for the pharmaceutical industry. Dissolution tests are performed to evaluate the dissolution properties of the compound and to ...
A study to discover novel biomarker glycoforms of lung cancer
(2019-08-28)
Lung cancer (LuCa) is the second most common cancer among both women and men. Detection of LuCa is usually very late, at an advanced inoperable stage, for which the 5 year survival rate is only 4%. Early detection of lung ...
Image-based isolation of single cells for sequencing
(2020-05-25)
Cancer is a complex disease characterized by unregulated cell division, resistance towards cell death, activated tissue invasion and the ability to metastasize. Tumors typically display heterogeneous mixture of cancer cells ...
Cross-talk between Foxp3 and HIC1 in human induced regulatory T cells
(2020-09-03)
Regulatory T cells (Tregs) are responsible for maintaining tolerance against autoimmunity and allergy by suppressing inappropriate immune responses in human immune system. Transcription factor Forkhead box p3 (Foxp3) is ...
Glycovariant Enabled Diagnosis of Renal Cell Carcinoma
(2019-06-24)
Renal Cell Carcinoma (RCC) has the highest mortality rate of the genitourinary cancers. Each year, around 273, 000 new cases are diagnosed. Prognosis for patients diagnosed with RCC is dependent on the stage when it is ...
Detection of antibodies to the hepatitis C virus using up-converting nanoparticles-based lateral flow immunoassay
(2019-02-05)
Hepatitis C virus (HCV), an RNA virus, causes acute hepatitis and frequently causes chronic hepatitis, which can lead to liver cirrhosis and primary liver cancer. In 2015, the WHO reported that HCV infection globally affects ...
Design of neonatal dried blood spot immunoassays for two novel biomarkers
(2018-11-23)
Spinal muscular atrophy (SMA) is a genetic disorder that leads to muscle weakness and atrophy and, in the most severe form, death before the age of two. It is caused by lack of survival of motor neuron (SMN) protein. ...