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Total energy intake, physical activity, body size and body composition determine total energy expenditure. An imbalance between total energy intake and total energy expenditure causes obesity. Overweight and obesity remains ...

ABSTRACT Patients with peripheral arterial disease (PAD) undergoing surgical revascularisation are in high risk of postoperative cardiovascular complications and death, due to advancing age and multiple comorbidities ...

Background: High physical activity and cardiorespiratory fitness may protect from the development of cardiometabolic disease outcomes but the mechanisms involved are not fully understood. Aims: The aims of this study ...

Heart failure (HF) is a global health problem. HF risk factors remain understudied. The roles that diabetes and sodium consumption play in HF remain unknown. Furthermore, the validity of HF diagnoses in the Finnish Hospital ...

ABSTRACT In coronary artery disease (CAD), the decision on revascularization is based on the hemodynamic significance of stenoses. However, this cannot directly be determined from the first-line anatomical imaging methods ...

The number of individuals affected by Type 2 diabetes mellitus (T2DM) is increasing rapidly nearly everywhere in the world. Insulin resistance, which means reduced impact of insulin in its target tissues, especially in the ...

Regulation of immune response is an important factor in determining progress of cardiometabolic diseases that may ultimately lead to atherosclerotic endpoints and premature death. Previous investigations have emphasized ...

The global epidemic of obesity is a challenge to healthcare systems due to the increase in the incidence of type 2 diabetes (T2D) and its associated morbidities. Although the small intestine is the first absorptive organ ...

While hypertension has been linked to various modifiable and fixed risk factors, the exact mechanisms behind blood pressure (BP) regulation and hypertension onset remain elusive. The rapid development in scientific branches ...

Cardiovascular disease is the leading cause of high mortality in advanced chronic kidney disease (CKD) patients. Treatment and prevention of cardiovascular disease should be in focus to improve prognosis in this high-risk ...