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Factors associated with improved outcomes in intensively treated early rheumatoid arthritis
(Turun yliopisto, 2018-01-12)
The cornerstone of the treatment of early rheumatoid arthritis (RA) is intensive, clinical remission targeted treatment with disease-modifying antirheumatic drugs (DMARDs). The aim of the present study was to elucidate ...
The Many faces of vasculitis: diagnostic challenges and economic burden
(Turun yliopisto, 2021-09-10)
The systemic vasculitides are characterized by inflammation of the blood vessel walls. Most vasculitides are idiopathic but sometimes a triggering event, e.g., medication, can be identified. Vessels of any type and size ...
Hybrid PET/CTA imaging for coronary artery disease: Studies on the effect of sex and genetic factors on diagnosis and outcome
(Turun yliopisto, 2024-05-25)
ABSTRACT
Coronary computed tomography angiography (CTA) enables non-invasive detection of coronary atherosclerosis and obstructive coronary artery disease (CAD). In turn, positron emission tomography angiography (PET) ...
Combined PET-MRI and small bowel capsule endoscopy in diagnostics and surveillance of small bowel Crohn’s disease
(Turun yliopisto, 2025-04-25)
Crohn’s disease (CD) is a chronic and relapsing inflammatory condition of the gut. Diagnostics of small bowel CD is difficult, as conventional endoscopy can only reach the proximal and distal ends of the small bowel. Cross ...
Nutritional determinants & cardiometabolic risk outcomes in children and adolescents with obesity
(Turun yliopisto, 2020-11-20)
Total energy intake, physical activity, body size and body composition determine total energy expenditure. An imbalance between total energy intake and total energy expenditure causes obesity. Overweight and obesity remains ...
Sleep-time predictors of cardiovascular complications in surgical peripheral arterial disease
(Turun yliopisto, 2019-06-14)
ABSTRACT
Patients with peripheral arterial disease (PAD) undergoing surgical revascularisation are in high risk of postoperative cardiovascular complications and death, due to advancing age and multiple comorbidities ...
Physical activity, cardiorespiratory fitness and cardiovascular health : the cardiovascular risk in young Finns study
(Turun yliopisto, 2018-01-19)
Background: High physical activity and cardiorespiratory fitness may protect from the development of cardiometabolic disease outcomes but the mechanisms involved are not fully understood.
Aims: The aims of this study ...
Heart failure – risk factors and the validity of diagnoses
(Turun yliopisto, 2022-08-19)
Heart failure (HF) is a global health problem. HF risk factors remain understudied. The roles that diabetes and sodium consumption play in HF remain unknown. Furthermore, the validity of HF diagnoses in the Finnish Hospital ...
Novel Imaging Approaches for the Detection of Hemodynamically Significant Coronary Artery Disease: Quantitative Flow Ratio and Artificial Intelligence-Based Ischemia Algorithm
(Turun yliopisto, 2024-06-08)
ABSTRACT
In coronary artery disease (CAD), the decision on revascularization is based on the hemodynamic significance of stenoses. However, this cannot directly be determined from the first-line anatomical imaging methods ...
Tissue-specific insulin sensitivity in humans - with special reference to the liver
(Turun yliopisto, 2019-03-09)
The number of individuals affected by Type 2 diabetes mellitus (T2DM) is increasing rapidly nearly everywhere in the world. Insulin resistance, which means reduced impact of insulin in its target tissues, especially in the ...