Viimeksi syötetyt Väitöskirjat
Aineistot 581-600 / 2989
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Controlled Decoration of Molecular Spherical Nucleic Acids
Turun yliopiston julkaisuja. Sarja A I, Chemica - Physica – Mathematica : 676 (Turun yliopisto, 31.10.2022)Research on therapeutically effective oligonucleotides (antisense oligonucleotides, ASOs and small interfering RNAs, siRNAs) has grown rapidly during the last decades. Oligonucleotide (ON) therapeutics are nowadays an ... -
Actin- and adhesion-mediated regulation of cell states : from cancer to stem cells
Turun yliopiston julkaisuja. Sarja D, Medica – Odontologica : 1670 (Turun yliopisto, 28.10.2022)Actin cytoskeleton and cell adhesion regulate cell shape, contractility and motility, all of which play important roles in development of normal tissues and diseases. Integrins are adhesion receptors that are connected ... -
Human microbiota: determining dietary factors on the journey from infants to adults
Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1666 (Turun yliopisto, 11.11.2022)The human microbiota profile changes with age from birth. The early colonisers of the infants’ guts are vital for their current health and also that in later ages of their lives. Determining factors affecting gut microbiota ... -
Neuropsychological correlates in substance use disorder
Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1663 (Turun yliopisto, 11.11.2022)Previous studies show contradictory results concerning associations with age of onset of substance use, differences between genders, and comorbid substance use in patients with mood disorders on neuropsychological performance. ... -
Molecular biomarkers in head and neck cancer: Evaluation of biomarkers in prognostication and radiotherapy response prediction
Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1665 (Turun yliopisto, 21.10.2022)Radiotherapy plays an integral part in the treatment of head and neck squamous cell carcinoma (HNSCC). Despite rigorous investigation spanning several decades, no molecular biomarkers are currently available for the ... -
Highlighting the chemical diversity of plants: modern tools for chemistry education
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser A I: Astronomica, Chemica, Mathematica : 673 (Turun yliopisto, 28.10.2022)The chemical diversity of plants is enormous as plants produce a variety of compounds that play key roles, for instance, in the growth, defence and reproduction of plants. This diversity is not well recognised in chemistry ... -
Left ventricular structure and function – Associations with cardiovascular risk factors from childhood to adulthood. The Cardiovascular Risk in the Young Finns Study
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica-Odontologica : 1667 (Turun yliopisto, 21.10.2022)Background: Despite improvements in the treatment of cardiovascular diseases, heart failure remains a challenge that causes considerable morbidity and mortality in aging populations. Left ventricular (LV) remodeling and ... -
Learning of second language sound contrasts: Effects of training on the perception and production of second language vowel and consonant duration
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser B: Humaniora : 589 (Turun yliopisto, 05.11.2022)Listen-and-repeat training has been shown to be an effective tool for the learning of non-native phoneme contrasts. The aim of this thesis was to examine the learning of non-native duration contrasts using short-term ... -
Observational studies of accreting X-ray pulsars in a broad energy range
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser A I: Astronomica, Chemica, Physica, Mathematica : 675 (Turun yliopisto, 04.11.2022)Among all interesting astrophysical objects in the universe, only a few are capable of improving our understanding of physics under extreme conditions. Accreting neutronstars are one of these objects. These compact objects ... -
Phenotypic and genetic subtyping of hypertension – toward personalized hypertension care
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica-Odontologica : 1655 (Turun yliopisto, 04.11.2022)Current knowledge of phenotypic and genotypic hypertension risk factors has not been effectively translated into personalized hypertension care. The aim of this thesis was to explore hypertension subtyping by applying ... -
Kapteenien vaimojen kokemus elämästä laivayhteisössä yhdysvaltalaisilla valaanpyyntialuksilla 1840–1870
Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. B: Humaniora : 591 (Turun yliopisto, 28.10.2022)Artikkeliväitöskirjassa tarkastellaan, kuinka kapteenien vaimot kirjoittivat päiväkirjateksteissään itsensä osaksi laivayhteisön elämää yhdysvaltalaisilla valaanpyyntialuksilla. Samalla he olivat tärkeä osa myös laajempaa ... -
Disturbances of glucose metabolism, cognitive decline, and neuroimaging changes related to Alzheimer's disease
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica-Odontologica : 1658 (Turun yliopisto, 14.10.2022)Insulin resistance is a common abnormal metabolic state related to obesity and many other health problems where target organs cannot respond normally to insulin. Insulin resistance and the dysfunction of the pancreatic ... -
The contemporary endovascular treatment of intracranial aneurysms
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica-Odontologica : 1662 (Turun yliopisto, 28.10.2022)The first endovascular treatment of intracranial aneurysms began with simple coiling in 1991. Ever since, it has developed significantly, and endovascular treatment is now the first choice for most intracranial aneurysms. ... -
Properties of highly magnetized neutron stars from X-ray timing analysis on different time scales
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser A I: Astronomica, Chemica, Mathematica : 672 (Turun yliopisto, 26.10.2022)Massive stars end their lives either by collapsing directly into a black hole or by exploding as a supernova, leaving behind their collapsed core, a black hole or a neutron star (NS). NSs are a showcase of extremities: ... -
Mesenchymal stromal cells and circulating angiogenic cells in vascularization
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser D: Medica-Odontologica : 1659 (Turun yliopisto, 14.10.2022)Vascularization is essential for tissue healing and reduced ability to regrow blood vessels can contribute, for example, to impaired wound healing and bone formation after injury. Generation of functional blood vessels is ... -
Chasing impact - how hybrid new ventures shape markets for sustainability
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser E: Oeconomica : 95 (Turun yliopisto. Turun kauppakorkeakoulu, 14.10.2022)This study contributes to the market-shaping research in the field of business-to-business marketing. Market shaping refers to the purposeful efforts of actors to change market characteristics or to construct new markets. ... -
Structural studies of glutathione transferases towards the development of novel applications and drug design
Turun yliopiston julkaisuja - Annales Universitatis Turkuensis, Ser A I: Astronomica, Chemica, Physica, Mathematica : 671 (Turun yliopisto, 21.10.2022)Glutathione transferases (GSTs) represent a ubiquitous large family of multifunctional enzymes which protect cellular macromolecules from reactive electrophiles. GSTs catalyse the nucleophilic addition of glutathione to ... -
Outcome of metal-on-metal hip arthroplasty: with special interest in repeated whole blood chromium and cobalt measurements
Turun yliopiston julkaisua - Annales Universitatis Turkuensis, Ser. D: Medica-Odontologica : 1660 (Turun yliopisto, 21.10.2022)It is now more than a decade since the full scale of problems with modern large diameter (LD) metal-on-metal (MoM) hip arthroplasties was recognized, leading to the withdrawal of most MoM implants around 2012. About 1.5 ... -
Bioprocessing of Alcoholic Beverages from Apples and Pears: Effects of Raw Materials and Processes on Quality
Doctoral Theses in Food Sciences at the University of Turku (Turun yliopisto, 07.10.2022)Alcoholic beverages made from non-grape fruits by fermentation, such as apple cider and pear perry, are increasingly popular nowadays, as well as being among the most commonly consumed products in recent years. In general, ... -
The phenotypic plasticity of thermal tolerance and its modulation in a complex environmental scenario
Turun yliopiston julkaisuja - Annales Universitatis TUrkuensis, Ser A II: Biologica - Geographica - Geologica : 390 (Turun yliopisto, 30.09.2022)It is well established that climate change constitutes a great challenge for wild animals, with increasing occurrence of heat waves also causing mortality events. However, in nature, environmental stressors are not occurring ...
