Viimeksi syötetyt 3. UTUCris-artikkelit
Aineistot 11841-11860 / 27094
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Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors
<p>The clinical significance of gene fusions detected by DNA-based next generation sequencing remains unclear as resistance mechanisms to EGFR tyrosine kinase inhibitors in EGFR mutant non-small cell lung cancer. By studying ... -
Clinical features and spectrum of NOTCH3 variants in Finnish patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL)
<p><strong>Objectives: </strong>Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a cerebral small vessel disease caused by pathogenic variants in the NOTCH3 gene. In ... -
Association of human myxovirus resistance protein A with severity of COVID-19
<p>Background<br></p><p>In this retrospective cohort study, we explored the correlation of blood human myxovirus resistance protein A (MxA) level with severity of disease in hospitalized COVID-19 patients.<br></p><p>Meth ... -
Radium-223 dichloride treatment in metastatic castration-resistant prostate cancer in Finland: A real-world evidence multicenter study
<p><strong>Background: </strong>Radium-233 dichloride is an alpha emitter that specifically targets bone metastases in prostate cancer. Results of a previously reported phase III randomized trial showed survival benefit ... -
Licensed Professionals and Intergenerational Big-, Meso- and Micro-Class Immobility within the Upper Class; Social Closure and Gendered Outcomes among Italian Graduates
This article examines how processes of social closure promote persistence at the top of the occupational hierarchy and how they vary by gender. We focus on the links between professional closure strategies and intergenerational ... -
Erilaisen koulutustaustan haava – ei-ylioppilaiden kokemuksia luokanopettajakoulutuksesta
Aikuiskasvatuksen vuosikirja -
Out of many modes and motivations. Ritualisation in Border Karelian Orthodox Christian feast and processions
<p>This article explores a sequence of events, a combination of Orthodox Christian village and chapel festivals, associated processions and a cross-border procession, through the theoretical concept of ritualisation. The ... -
SN 2020wnt: a slow-evolving carbon-rich superluminous supernova with no O II lines and a bumpy light curve
We present the analysis of SN 2020wnt, an unusual hydrogen-poor superluminous supernova (SLSN-I), at a redshift of 0.032. The light curves of SN 2020wnt are characterized by an early bump lasting similar to 5 d, followed ... -
Experience Goods, Umbrella Branding, and Reputation
<p>This paper examines umbrella brands—brand stretching or brand extension—in a model of experience goods and an infinite number of periods. A monopoly firm has short-run incentives to compromise on product quality so as ... -
Multidisciplinary History of Goats in Finland: A Comparative Approach
<p>This article aims to study the history of goats (Capra hircus) in Finland using a multisource<br>approach combining zooarchaeological data with evidence from written sources, the Silver Tax<br>Record of 1571, and ... -
Mechanical Properties Evaluation of Three Different Materials for Implant Supported Overdenture: An In-Vitro Study
<p><b>Aim:</b> <br></p><p>the aim of this study was to compare the flexural strength and elastic modulus of three-dimensionally (3D) printed, conventional heat-cured, and high-impact implant-supported overdenture materials ... -
Family members’ experiences of psychosocial support in palliative care inpatient units: A descriptive qualitative study
<p>Purpose</p><p>The support for family members (FMs) during a patient's palliative hospital care has been rarely studied, creating a gap in how FMs can be better supported. Psychosocial support answers widely to FMs' ... -
Hardship at birth alters the impact of climate change on a long-lived predator
<p>Climate change is increasing the frequency of extreme events, such as droughts or hurricanes, with substantial impacts on human and wildlife communities. Extreme events can affect individuals through two pathways: by ... -
Recontacting biobank participants to collect lifestyle, behavioural and cognitive information via online questionnaires: lessons from a pilot study within FinnGen
<p><b>Objectives </b><br></p><p>To recontact biobank participants and collect cognitive, behavioural and lifestyle information via a secure online platform. <br></p><p><b>Design </b><br></p><p>Biobank-based recontacting ... -
Academic-practice partnerships in evidence-based nursing practice: a scoping review protocol
<p><b>Introduction </b><br></p><p>Academic-practice partnerships are a promising strategy that could strengthen the promotion and innovation of evidence-based nursing practice (EBNP). However, there is little evidence of ... -
Appendiceal microbiome in uncomplicated and complicated acute appendicitis: A prospective cohort study
<p>Uncomplicated and complicated acute appendicitis seem to be two different forms of this common abdominal emergency. The contribution of appendiceal microbiota to appendicitis pathogenesis has been suggested, but differences ... -
Delirium in a surgical context from a nursing perspective: A hybrid concept analysis
<p>Background</p><p>The term delirium has been defined in medical diagnosis criteria as a multidimensional disorder, and the term acute confusion is included in nursing classifications. Delirium can be a serious complication ... -
Microstructure and Mechanical Properties of Steel and Ni-Based Superalloy Joints for Rotors of High-Speed Electric Motors
High-speed electric motors, e.g., axially laminated anisotropic synchronous reluctance motors (ALA-SynRM), use a solid rotor manufactured by joining alternating layers of magnetic and non-magnetic metallic sheets. The ... -
Performing journalism: Making sense of ethical practice within local interloper media
<p>This paper explores the blurring boundaries between local journalism, strategic and marketing communications and civic information. The study at hand produces new knowledge regarding the conceptions and practices that ...