Viimeksi syötetyt 3. UTUCris-artikkelit

Aineistot 11921-11940 / 27094

    • Robust strategies in nuclear-targeted cancer therapy based on functional nanomaterials 

      Qin Xiaofei; Zhang Hanyi; Xing Xin; Wang Peng; Yan Jiaqi; Liu Daishun; Gong Qiuyu; Zhang Renshuai; Zhang Hongbo
      Nucleus, as the machinery for genome transcription, play prominent roles to support the fundamental cel-lular functions, the destruction of any of these specific parts would significantly modulate the cell function. ...

    • Towards sustainable mobility – Transformative scenarios for 2034 

      Kiviluoto Katariina; Tapio Petri; Tuominen Anu; Lyytimäki Jari; Ahokas Ira; Silonsaari Jonne; Schwanen Tim
      <p>Increasing the share of walking and cycling is one of the building blocks of sustainable mobility transformation. Fundamental changes are needed in society and urban structure to support the integration of walking and ...

    • Deep learning prediction of non-perfused volume without contrast agents during prostate ablation therapy 

      Wright Cameron; Mäkelä Pietari; Bigot Alexandre; Anttinen Mikael; Boström Peter J.; Blanco Sequeiros Blanco
      <p>The non-perfused volume (NPV) is an important indicator of treatment success immediately after prostate ablation. However, visualization of the NPV first requires an injection of MRI contrast agents into the bloodstream, ...

    • Rethinking the Intrinsic Sensitivity of Fungi to Glyphosate 

      Tall Tuomas; Puigbò Pere
      The 5-enolpyruvylshikimate 3-phosphate synthase (EPSPS) is the central enzyme of the shikimate pathway to synthesize the three aromatic amino acids in fungi, plants, and prokaryotes. This enzyme is the target of the herbicide ...

    • Intelligent Control of Seizure-Like Activity in a Memristive Neuromorphic Circuit based on the Hodgkin-Huxley Model 

      Moreira Bessa Wallace; Lima Gabriel da Silva
      <p>Memristive neuromorphic systems represent one of the most promising technologies to overcome the current challenges faced by conventional computer systems. They have recently been proposed for a wide variety of applications, ...

    • Oral Cavity Calprotectin and Lactoferrin Levels in Relation to Radiotherapy 

      Keskin Mutlu; Kompuinen Jenna; Harmankaya İlknur; Karaçetin Didem; Nissilä Verneri; Gürsoy Mervi; Sorsa Timo; Gürsoy Ulvi Kahraman
      <p><strong>Background: </strong>Lactoferrin, an iron-binding glycoprotein, and calprotectin, a calcium binding protein, are sensitive markers of inflammation and their fecal levels increase during radiotherapy of prostate ...

    • Detailed prenatal and postnatal MRI findings and clinical analysis of RAF1 in Noonan syndrome 

      Helenius Kjell; Parkkola Riitta; Arola Anita; Peltola Ville; Haanpää Maria K
      Noonan syndrome is a genetically heterogeneous developmental disorder, which usually includes findings such as short stature, facial dysmorphia, cardiac abnormalities and a varying degree of intellectual disability. We ...

    • Using personalized prognosis in the treatment of relapsing multiple sclerosis: A practical guide 

      Van Wijmeersch Bart; Hartung Hans-Peter; Vermersch Patrick; Pugliatti Maura; Pozzilli Carlo; Grigoriadis Nikolaos; Alkhawajah Mona; Airas Laura; Linker Ralf; Oreja-Guevara Celia
      The clinical course of multiple sclerosis (MS) is highly variable among patients, thus creating important challenges for the neurologist to appropriately treat and monitor patient progress. Despite some patients having ...

    • Book Review: The New Patriarchs of Digital Capitalism: Celebrity Tech Founders and Networks of Power by Ben Little and Allison Winch 

      Koskinen Henri

    • BRAFV600E Expression in Thyrocytes Causes Recruitment of Immunosuppressive STABILIN-1 Macrophages 

      Spourquet Catherine; Delcorte Ophélie; Lemoine Pascale; Dauguet Nicolas; Loriot Axelle; Achouri Younes; Hollmén Maija; Jalkanen Sirpa; Huaux Francois; Lucas Sophie; Meerkeeck Pierre Van; Knauf Jeffrey A; Fagin James A; Dessy Chantal; Mourad Michel; Henriet Patrick; Tyteca Donatienne; Marbaix Etienne; Pierreux Christophe E
      Papillary thyroid carcinoma (PTC) is the most frequent histological subtype of thyroid cancers (TC), and BRAF<sup>V600E</sup> genetic alteration is found in 60% of this endocrine cancer. This oncogene is associated with ...

    • The relationships between use of alcohol, tobacco and coffee in adolescence and mood disorders in adulthood 

      Bolstad Ingeborg; Alakokkare Anni-Emilia; Bramness Jorgen G.; Rognli Eline B.; Levola Jonna; Mustonen Antti; Miettunen Jouko; Niemelä Solja
      <p><b>Introduction: </b>Alcohol, tobacco and coffee are commonly used substances and use in adolescence has previously been linked to mood disorders. However, few large prospective studies have investigated adolescent use ...

    • Increased lesion depth, higher body mass index and older age are risk factors for osteoarthritis during long-term follow-up in patients with osteochondritis dissecans of the knee 

      Ekman Elina; Nevalainen Sepe; Karjalainen Elina; Kohonen Ia; Vuohelainen Jimi; Rissanen Tiia; Itälä Ari
      <p><b>Introduction </b>To report on the long-term prognosis of osteochondritis dissecans (OCD) patients regarding radiological and patient-reported outcomes and to analyze possible risk factors. <br></p><p><b>Materials and ...

    • Transition to emerging adulthood during the COVID-19 pandemic: Changes in anxiety and the role of inclusion/exclusion experiences 

      Repo Juuso; Herkama Sanna; Yanagida Takuya; Salmivalli Christina
      <p>The study investigated a developmentally sensitive group, emerging adults going through a critical post-secondary educational transition in tandem with the first wave of the COVID pandemic in Finland. The participants ...

    • Loneliness, subjective health complaints, and medicine use among Finnish adolescents 2006-2018 

      Lyyra Nelli; Junttila Niina; Tynjälä Jorma; Villberg Jari; Välimaa Raili
      <p><i>Aims</i>: Loneliness is an important public health challenge for all ages. This study reports time trends of loneliness among adolescents over a 12-year period and analyses the strength of the associations between ...

    • Lapsuuden elintapojen ja elinympäristön merkitys valtimoterveydelle 

      Laitinen Tomi T; Juonala Markus; Pahkala Katja

    • Vakavasti sairaan aikuispotilaan tehohoidon rajaaminen 

      Valtonen Mika; Lönnroos Eija; Pietiläinen Laura; Reinikainen Matti

    • The BepiColombo Environment Radiation Monitor, BERM 

      Pinto Marco; Sanchez-Cano Beatriz; Moissl Richard; Benkhoff Johannes; Cardoso Carlota; Goncalves Patrícia; Assis Pedro; Vainio Rami; Oleynik Philipp; Lehtolainen Arto; Grande Manuel; Marques Arlindo
      The BepiColombo Environment Radiation Monitor (BERM) on board the European Space Agency's Mercury Planetary Orbiter (MPO), is designed to measure the radiation environment encountered by BepiColombo. The instrument measures ...

    • One-Pot Transformation of Citronellal to Menthol Over H-Beta Zeolite Supported Ni Catalyst: Effect of Catalyst Support Acidity and Ni Loading 

      Taghavi Somayeh; Mäki-Arvela Päivi; Vajglová Zuzana; Peurla Markus; Angervo Ilari; Eränen Kari; Ghedini Elena; Menegazzo Federica; Zendehdel Mojgan; Signoretto Michela; Murzin Dmitry Yu.
      Citronellal was converted to menthol in a one-pot approach using H-Beta zeolite-based Ni catalyst in a batch reactor at 80 degrees C, under 20 bar of total pressure. The effects of H-Beta acidity (H-Beta-25 with the molar ...

    • Seurustelusuhdeväkivalta tyttöjen pahoinpitelyistä tehdyissä rikosilmoituksissa 

      Anu Isotalo

    • Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention 

      Wang Zhe; Emmerich Andrew; Pillon Nicolas J.; Moore Tim; Hemerich Daiane; Cornelis Marilyn C.; Mazzaferro Eugenia; Broos Siacia; Ahluwalia Tarunveer S.; Bartz Traci M.; Bentley Amy R.; Bielak Lawrence F.; Chong Mike; Chu Audrey Y.; Berry Diane; Dorajoo Rajkumar; Dueker Nicole D.; Kasbohm Elisa; Feenstra Bjarke; Feitosa Mary F.; Gieger Christian; Graff Mariaelisa; Hall Leanne M.; Haller Toomas; Hartwig Fernando P.; Hillis David A.; Huikari Ville; Heard-Costa Nancy; Holzapfel Christina; Jackson Anne U.; Johansson Åsa; Jørgensen Anja Moltke; Kaakinen Marika A.; Karlsson Robert; Kerr Kathleen F.; Kim Boram; Koolhaas Chantal M.; Kutalik Zoltan; Lagou Vasiliki; Lind Penelope A.; Lorentzon Mattias; Lyytikäinen Leo-Pekka; Mangino Massimo; Metzendorf Christoph; Monroe Kristine R.; Pacolet Alexander; Pérusse Louis; Pool Rene; Richmond Rebecca C.; Rivera Natalia V.; Robiou-du-Pont Sebastien; Schraut Katharina E.; Schulz Christina-Alexandra; Stringham Heather M.; Tanaka Toshiko; Teumer Alexander; Turman Constance; van der Most Peter J.; Vanmunster Mathias; van Rooij Frank J. A.; van Vliet-Ostaptchouk Jana V.; Zhang Xiaoshuai; Zhao Jing-Hua; Zhao Wei; Balkhiyarova Zhanna; Balslev-Harder Marie N.; Baumeister Sebastian E.; Beilby John; Blangero John; Boomsma Dorret I.; Brage Soren; Braund Peter S.; Brody Jennifer A.; Bruinenberg Marcel; Ekelund Ulf; Liu Ching-Ti; Cole John W.; Collins Francis S.; Cupples L. Adrienne; Esko Tõnu; Enroth Stefan; Faul Jessica D.; Fernandez-Rhodes Lindsay; Fohner Alison E.; Franco Oscar H.; Galesloot Tessel E.; Gordon Scott D.; Grarup Niels; Hartman Catharina A.; Heiss Gerardo; Hui Jennie; Illig Thomas; Jago Russell; James Alan; Joshi Peter K.; Jung Taeyeong; Kähönen Mika; Kilpeläinen Tuomas O.; Koh Woon-Puay; Kolcic Ivana; Kraft Peter P.; Kuusisto Johanna; Launer Lenore J.; Li Aihua; Linneberg Allan; Luan Jian’an; Vidal Pedro Marques; Medland Sarah E.; Milaneschi Yuri; Moscati Arden; Musk Bill; Nelson Christopher P.; Nolte Ilja M.; Pedersen Nancy L.; Peters Annette; Peyser Patricia A.; Power Christine; Raitakari Olli T.; Reedik Mägi; Reiner Alex P.; Ridker Paul M.; Rudan Igor; Ryan Kathy; Sarzynski Mark A.; Scott Laura J.; Scott Robert A.; Sidney Stephen; Siggeirsdottir Kristin; Smith Albert V.; Smith Jennifer A.; Sonestedt Emily; Strøm Marin; Tai E. Shyong; Teo Koon K.; Thorand Barbara; Tönjes Anke; Tremblay Angelo; Uitterlinden Andre G.; Vangipurapu Jagadish; van Schoor Natasja; Völker Uwe; Willemsen Gonneke; Williams Kayleen; Wong Quenna; Xu Huichun; Young Kristin L.; Yuan Jian Min; Zillikens M. Carola; Zonderman Alan B.; Ameur Adam; Bandinelli Stefania; Bis Joshua C.; Boehnke Michael; Bouchard Claude; Chasman Daniel I.; Smith George Davey; de Geus Eco J. C.; Deldicque Louise; Dörr Marcus; Evans Michele K.; Ferrucci Luigi; Fornage Myriam; Fox Caroline; Garland Theodore Jr; Gudnason Vilmundur; Gyllensten Ulf; Hansen Torben; Hayward Caroline; Horta Bernardo L.; Hyppönen Elina; Jarvelin Marjo-Riitta; Johnson W. Craig; Kardia Sharon L. R.; Kiemeney Lambertus A.; Laakso Markku; Langenberg Claudia; Lehtimäki Terho; Le Marchand Loic; Lifelines Cohort Study; Magnusson Patrik K. E.; Martin Nicholas G.; Melbye Mads; Metspalu Andres; Meyre David; North Kari E.; Ohlsson Claes; Oldehinkel Albertine J.; Orho-Melander Marju; Pare Guillaume; Park Taesung; Pedersen Oluf; Penninx Brenda W. J. H.; Pers Tune H.; Polasek Ozren; Prokopenko Inga; Rotimi Charles N.; Samani Nilesh J.; Sim Xueling; Snieder Harold; Sørensen Thorkild I. A.; Spector Tim D.; Timpson Nicholas J.; van Dam Rob M.; van der Velde Nathalie; van Duijn Cornelia M.; Vollenweider Peter; Völzke Henry; Voortman Trudy; Waeber Gérard; Wareham Nicholas J.; Weir David R.; Wichmann Heinz-Erich; Wilson James F.; Hevener Andrea L.; Krook Anna; Zierath Juleen R.; Thomis Martine A. I.; Loos Ruth J. F.; den Hoed Marcel
      Although physical activity and sedentary behavior are moderately heritable, little is known about the mechanisms that influence these traits. Combining data for up to 703,901 individuals from 51 studies in a multi-ancestry ...