Viimeksi syötetyt 3. UTUCris-artikkelit
Aineistot 15081-15100 / 27094
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Drug-to-Antibody Ratio Estimation via Proteoform Peak Integration in the Analysis of Antibody-Oligonucleotide Conjugates with Orbitrap Fourier Transform Mass Spectrometry
The therapeutic efficacy and pharmacokinetics of antibody-drug conjugates (ADCs) in general, and antibody-oligonucleotide conjugates (AOCs) in particular, depend on the drug-to-antibody ratio (DAR) distribution and average ... -
Teaching limited compression ultrasound to general practitioners reduces referrals of suspected DVT to a hospital: a retrospective cross-sectional study
<p><strong>Background</strong> <br></p><p>The aim of this study was to retrospectively determine whether teaching limited compression ultrasound (LCUS) to general practitioners (GP) would reduce the number of patients with ... -
Polymerization Shrinkage of Short Fiber Reinforced Dental Composite Using a Confocal Laser Analysis
The purpose of this study was to investigate the polymerization shrinkage of short fiber reinforced composite (SFRC) using a multicolor confocal displacement laser that can measure the polymerization shrinkage with high ... -
Uusien aikaorientaatioiden ongelma taidehistoriassa – anakronismi, kronotopia ja heterokronia
<p>Tarkastelen artikkelissani taidehistoriallisessa tutkimuksessa viime aikoina yleistyneen anakronistisen asenteen eri näkökohtia. Pohdin, voiko anakronistinen asennoituminen murtaa ns. lineaarisen aikakäsityksen? Punnitsen ... -
Maternal Anxiety Symptoms and Self-Regulation Capacity Are Associated With the Unpredictability of Maternal Sensory Signals in Caregiving Behavior
The unpredictability of maternal sensory signals in caregiving behavior has been recently found to be linked with infant neurodevelopment. The research area is new, and very little is yet known, how maternal anxiety and ... -
Novel renal markers for the assessment of renal integrity in patients undergoing knee arthroplasty - a pilot study
The feasibility of novel kidney injury biomarkers in consecutive patients having total knee arthroplasty with local infiltration analgesia was evaluated.\nWe enrolled 30 patients scheduled for elective unilateral total ... -
Sharp growth conditions for boundedness of maximal function in generalized Orlicz space
<p>We study sharp growth conditions for the boundedness of the Hardy-Littlewood maximal function in the generalized Orlicz spaces. We assume that the generalized Orlicz function satisfies the standard continuity properties ... -
Enabling Technologies of Industry 4.0 and Their Global Forerunners: An Empirical Study of the Web of Science Database
Communications in Computer and Information Science<p>Knowledge management in organizations brings many benefits for R&D operations of companies and corporations. This empirical study demonstrates the power of large database analyses for industrial strategies and policy. ... -
Researching disasters and disaster management in China: Persistent questions and emerging trends
<p>This article offers an introduction to the China Information’s special issue on disasters and<br />disaster management. It is argued here that studying disasters and disaster management<br />should not only improve our ... -
ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors
Poor chemotherapy response remains a major treatment challenge for high-grade serous ovarian cancer. Cancer stem cells are the major contributors to relapse and treatment failure as they can survive conventional therapy. ... -
Brain free fatty acid uptake is elevated in morbid obesity, and is irreversible 6 months after bariatric surgery: A positron emission tomography study
<h3>Aim</h3><p>To investigate whether there are differences in brain fatty acid uptake (BFAU) between morbidly obese and lean subjects, and the effect of weight loss following bariatric surgery.</p><h3>Materials and ... -
Network controllability solutions for computational drug repurposing using genetic algorithms
Control theory has seen recently impactful applications in network science, especially in connections with applications in network medicine. A key topic of research is that of finding minimal external interventions that ... -
Assembly of Bleomycin Saccharide-Decorated Spherical Nucleic Acids
<p>Glyco-decorated spherical nucleic acids (SNAs) may be attractive delivery vehicles, emphasizing the sugar-specific effect on the outer sphere of the construct and at the same time hiding unfavorable distribution properties ... -
Low-saturated-fat and low-cholesterol diet does not alter pubertal development and hormonal status in adolescents
<p><br />Aim<br />The aim was to assess the influence of dietary counselling on the pubertal development and hormonal status in healthy adolescents.<br /><br />Methods<br />We used a subcohort of 193 healthy boys (52%) and ... -
Parenting Fears and Concerns during Pregnancy: A Qualitative Survey
<p>Previous research on the fears and anxieties of expectant mothers has focused mostly on their fears about giving birth rather than parenting. This study aims to describe mothers’ fears and concerns about parenthood ...
