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Physical activity in asthma control and its immune modulatory effect in asthmatic preschoolers
<p><b>Background:</b> The impact of physical activity on immune response is a hot topic in exercise immunology, but studies involving asthmatic children are scarce. Our aims were to examine whether there were any differences ...
Clinical correlates of rhinovirus infection in preschool asthma
Background Investigation of preschool asthma is important since not all children outgrow their illness during this age. Data are scarce on the role of rhinovirus (RV) infections in this patient group. Objectives To investigate ...
Childhood asthma outcomes during the COVID-19 pandemic: Findings from the PeARL multinational cohort
<p>Background <br></p><p>The interplay between COVID-19 pandemic and asthma in children is still unclear. We evaluated the impact of COVID-19 pandemic on childhood asthma outcomes.<br></p><p>Methods <br></p><p>The PeARL ...
Management of asthma in childhood: study protocol of a systematic evidence update by the Paediatric Asthma in Real Life (PeARL) Think Tank
<p>Introduction</p><p>Clinical recommendations for childhood asthma are often based on data extrapolated from studies conducted in adults, despite significant differences in mechanisms and response to treatments. The ...
Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) drives the resolution of allergic asthma
RANTES is implicated in allergic asthma and in T cell-dependent clearance of infection. RANTES receptor family comprises CCR1, CCR3, and CCR5, which are G-protein-coupled receptors consisting of seven transmembrane helices. ...