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Background: Gestational diabetes mellitus (GDM) is characterized by disturbed glucose metabolism and activation of low-grade inflammation. We studied whether metformin treatment has favorable or unfavorable effects on ...

<p>Aims<br />To compare the effects of metformin and insulin treatment on maternal serum lipids in patients with gestational diabetes (GDM), and to analyse the associations between individual lipids and birth weight (BW).<br ...

<h4>BACKGROUND & AIMS: </h4><p>Excessive adiposity and gestational weight gain (GWG) have been linked with maternal and offspring morbidity. We investigated the relation of maternal diet, physical activity and GWG ...

<h4>CONTEXT: </h4><p>To the best of our knowledge, no previous studies have examined the role of youth calcium intake in the development of impaired glucose metabolism, especially those with long-term high calcium ...

Background: Increased intestinal permeability may precede adverse metabolic conditions. The extent to which the composition of the gut microbiota and diet contribute to intestinal permeability during pregnancy is ...

<p>Recent evidence has shown the importance of gut microbiota in human metabolic health [<a href="https://link.springer.com/article/10.1007/s00592-017-1056-0#CR1" title="View reference">1</a>]. Gut microbiota dysbiosis in ...

<p>Abstract</p><p>Introduction Gestational diabetes mellitus (GDM) is a common disorder of pregnancy and contributes to adverse pregnancy outcomes. Metformin is often used for the prevention and management of GDM; however, ...

<p>Aim The aim was to determine temporal changes in increased risk of epilepsy among children with type 1 diabetes.</p><p>Methods The incidence of epilepsy up to age 15 in children with prior type 1 diabetes was analysed ...

<p>Aims: We compared the effects of metformin and insulin treatments of gestational diabetes mellitus (GDM) on amino acid metabolism.<br /><br />Methods: 217 pregnant women diagnosed with GDM were randomized to receive ...

<div><h3>Objectives</h3><p>Body composition measurements with air displacement plethysmography (ADP) define body volume, which must be corrected for thoracic gas volume (TGV). We hypothesized that physiologic changes owing to pregnancy could affect the accuracy of predicted TGV and introduce errors into body composition measurements.</p></div><div><h3>Methods</h3><p>We investigated the effect of measuring versus predicting TGV on the accuracy of body composition calculations measured with ADP in overweight and obese pregnant women. The fat and fat-free masses of 110 women were determined with ADP with predicted and measured TGV.</p></div><div><h3>Results</h3><p>Measured TGV decreased from early to late pregnancy (P = 0.0002). Compared with measured TGV, predicted TGV was 6.3% higher during early gestation and 12.6% higher during late gestation (both P ≤ 0.001). The use of predicted instead of measured TGV in body composition calculations resulted in an overestimation of fat mass by 0.8% during the early stage, and 2.6% during the late stage of pregnancy (both P ≤ 0.001).</p></div><div><h3>Conclusions</h3><p>Measuring TGV increases the accuracy of body composition measurement by ADP in overweight and obese women, particularly during the late stage of pregnancy.</p></div>...