Youth and Long-Term Dietary Calcium Intake With Risk of Impaired Glucose Metabolism and Type 2 Diabetes in Adulthood
Feitong Wu; Olli T Raitakari; Tomi Laitinen; Terho Lehtimäki; Matthew A Sabin; Markus Juonala; Costan G Magnussen; Jorma S A Viikari; Tapani Rönnemaa; Mika Kähönen; Nina Hutri-Kähönen; Antti Jula; Niina Pitkänen; Marie-Jeanne Buscot; Katja Pahkala
https://urn.fi/URN:NBN:fi-fe2021042824042
Tiivistelmä
CONTEXT:
To the best of our knowledge, no previous studies have examined the role of youth calcium intake in the development of impaired glucose metabolism, especially those with long-term high calcium intake.
OBJECTIVES:
To examine whether youth and long-term (between youth and adulthood) dietary calcium intake is associated with adult impaired glucose metabolism and type 2 diabetes (T2D).
DESIGN, SETTING, AND PARTICIPANTS:
The Cardiovascular Risk in Young Finns Study is a 31-year prospective cohort study (n = 1134; age, 3 to 18 years at baseline).
EXPOSURES:
Dietary calcium intake was assessed at baseline (1980) and adult follow-up visits (2001, 2007, and 2011). Long-term (mean between youth and adulthood) dietary calcium intake was calculated.
MAIN OUTCOME MEASURES:
Adult impaired fasting glucose (IFG) and T2D.
RESULTS:
We found no evidence for nonlinear associations between calcium intake and IFG or T2D among females and males (all P for nonlinearity > 0.05). Higher youth and long-term dietary calcium intake was not associated with the risk of IFG or T2D among females or males after adjustment for confounders, including youth and adult body mass index.
CONCLUSIONS:
Youth or long-term dietary calcium intake is not associated with adult risk of developing impaired glucose metabolism or T2D.
Kokoelmat
- Rinnakkaistallenteet [19207]