Viimeksi syötetyt Rinnakkaistallenteet
Aineistot 1221-1240 / 29337
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Genominen tieto levinneen eturauhassyövän hoidossa
Homologiseen rekombinaatioon (HR) liittyvien geenien somaattisilla ja ituratamuutoksilla on keskeinen merkitys eturauhassyövän kehittymisessä. Noin 9 \%:lla etäpesäkkeisistä kastraatioresistenttiä eturauhassyöpää (mCRPC) ... -
Lapsen sydämen sivuääni
Sydämen sivuääni on tavallinen löydös terveillä lapsilla. Oireettoman lapsen sivuääni on useimmiten hyvänlaatuinen, mutta joskus taustalta löytyy seurantaa tai hoitoa vaativa rakenteellinen sydänvika. Rakennepoikkeavuudet ... -
Children’s physical custody arrangements and mothers’ employment in 11 European countries
As joint physical custody (JPC) of children after parental separation has become more prevalent across countries, we need to know more about its impacts. This study examines whether JPC is associated with mother's paid ... -
Unrelated donor transplantation with posttransplant cyclophosphamide vs ATG for myelodysplastic neoplasms
Prospective randomized trials have reported a benefit for anti-thymocyte globulin (ATG)-based graft-versus-host disease (GvHD) prophylaxis in the setting of allogeneic hematopoietic stem cell transplantation (Allo-HSCT) ... -
The SIMPLIFY Protocol: A Monophasic Extraction System Suitable for Exposomics, Metabolomics, Lipidomics, and Proteomics Research
<p>Advancing our understanding of human health and disease requires comprehensive analytical approaches capable of capturing the complex interplay between endogenous metabolism and environmental exposures. A major challenge ... -
SNP genotypes in CYP2C9 and VKORC1 genes do not affect prostate cancer or cancer mortality among warfarin users in Finnish prostate cancer patients
<p>The coagulation cascade is thought to contribute to cancer progression. Although <em>in vitro</em> studies suggest that anticoagulants, such as warfarin, might reduce cancer progression, epidemiological data indicate ... -
NGC 6860, Mrk 915, and MCG -01-24-012
We present a study of the cold molecular versus ionized gas distribution in three nearby Seyfert galaxies: NGC 6860, Mrk 915, and MCG -01-24-012. To constrain the cold molecular flux distribution at similar to 0.5-0.8 '' ... -
Duration and mode of delivery: Does maternal sleep matter?
<h3>Objective</h3><p>Poor sleep quality in late pregnancy has been identified as a risk factor for operative deliveries. In this study, we investigated the associations between maternal sleep throughout pregnancy and its ... -
National waiting time monitoring in oral healthcare - The role of triage dental nurses
<p>OBJECTIVES: Our study analyzed dental nurses' use and use behavior determinants of electronic patient IS modules in telephone triage. The modules were implemented in public oral healthcare organizations' patient ISs to ... -
Levodopa exposure and nigral neuroinflammation in parkinsonian disorders: A postmortem study of 63 cases
<p>Levodopa remains the cornerstone of treatment in Parkinson’s disease (PD), but its long-term impact on neuroinflammation remains unclear, particularly in multiple system atrophy (MSA) and progressive supranuclear palsy ... -
Effects of antiresorptives and Co-medications on 3D gingival cell Co-cultures
<h3>Introduction</h3><p>Bisphosphonates and denosumab are the most common antiresorptive drugs (ARs). ARs may cause medication-related osteonecrosis of the jaw (MRONJ) as a side effect, characterized by osteonecrosis and ... -
On the Intersections of q-ary Hamming Balls
<p>In this article, we study the cardinality of the intersection of multiple q-ary Hamming balls for q ≥ 3. The problem has previously been studied in the binary case and for two balls in the case of q ≥ 3. When each ball ... -
High-resolution ALMA observations of H2S in LIRGs: Dense gas and shocks in outflows and circumnuclear disks
<p><b>Context</b><br></p><p><em></em>Molecular gas plays a critical role in regulating star formation and nuclear activity in galaxies. Sulphur-bearing molecules, such as H<sub>2</sub>S, are sensitive to the physical and ... -
Formulation and evaluation of poly(jasmine lactone) based micelles for improving the oral permeability of acyclovir
Acyclovir (ACV), an antiviral drug, belongs to the BCS class III drug with intermediate solubility and low permeability. The limited permeability leads to low drug absorption, making it poorly bioavailable. Consequently, ... -
Early Emerging Gradients in Children's Eye Movement Times Across Levels of Household Resources
Studies in low-resource settings suggest that multiple aspects of early childhood development are sensitive to the relative poverty of a child's environment. We examined whether direct, quantitative measures of early ... -
From toxicity assessment to adaptive safety care: implementing comprehensive fast-track safety evaluation for anticancer drug development
<h3>Background</h3><p>The conventional drug development pathway in oncology, spanning 10-15 years, has long been slow, costly, and complex, often marked by late-stage failures due to efficacy or safety concerns.</p><h3>Materials ... -
To conform or to perform - the dilemma of director's attributes in agricultural cooperatives
<p><span>Research related to cooperative boards has highlighted dilemmas and tensions related to board characteristics and director's simultaneous role as representatives of membership groups and as board experts. Cooperative ... -
Grasping a Handful: Sequential Multi-Object Dexterous Grasp Generation
We introduce the sequential multi-object robotic grasp sampling algorithm SeqGrasp that can robustly synthesize stable grasps on diverse objects using the robotic hand’s partial Degrees of Freedom (DoF). We use SeqGrasp ... -
Improving patient positioning and posture for breast cancer radiotherapy using DIBH and SGRT techniques by modifying fixation devices and tightening SGRT tolerances
<p><b>Background:</b> Surface guided radiotherapy (SGRT) aids to place the patient in the correct position before radiotherapy. The aim of this retrospective observational study was to investigate how modifying patient ... -
Administration of patient education in nursing: perspective of nurse administrators in Finland
<p>Aim: To analyze administration of patient education in nursing from the perspective of nurse administrators to provide new information and support for evidence-based practice and development.<br></p><p>Design: A descriptive ...
