Viimeksi syötetyt Rinnakkaistallenteet
Aineistot 15981-16000 / 19218
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Early CD8+-recovery independently predicts low probability of disease relapse but also associates with severe GVHD after allogeneic HSCT
<p>In this single-center study we retrospectively evaluated the impact of early reconstitution of different lymphocyte subsets on patient outcomes after allogeneic hematopoietic stem cell transplantation (allo-HSCT). We ... -
Impact of deep learning-determined smoking status on mortality of cancer patients: never too late to quit
<p>Background<br>Persistent smoking after cancer diagnosis is associated with increased overall mortality (OM) and cancer mortality (CM). According to the 2020 Surgeon General's report, smoking cessation may reduce CM but ... -
Socioeconomic position and intergenerational associations of ideal health behaviors
<p>Background: Promoting ideal cardiovascular health behaviors is an objective of the American Heart Association 2020 goals. We hypothesized that ideal health behaviors of parents are associated with health behaviors of ... -
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies
TP53, which encodes the tumor suppressor p53, is the most frequently mutated gene in human cancer. The selective pressures shaping its mutational spectrum, dominated by missense mutations, are enigmatic, and neomorphic ... -
Using Gabmap
<p> Gabmap is a freely available, open-source web application that analyzes the data of language variation, e.g. varying words for the same concepts, varying pronunciations for the same words, or varying frequencies of ... -
Surgery or conservative treatment for rotator cuff tear: a meta-analysis
<p><b>Purpose:</b> Comparative evidence on treating rotator cuff tear is inconclusive. The objective of this review was to evaluate the evidence on effectiveness of tendon repair in reducing pain and improving function of ... -
The effect of enzyme replacement therapy on clinical outcomes in male patients with Fabry disease: A systematic literature review by a European panel of experts
Background: Enzyme replacement therapy (ERT) with recombinant human a-galactosidase has been available for the treatment of Fabry disease since 2001 in Europe and 2003 in the USA. Treatment outcomes with ERT are dependent ... -
Genetically defined syngeneic mouse models of ovarian cancer as tools for the discovery of combination immunotherapy
Despite advances in immuno-oncology, the relationship between tumor genotypes and response to immunotherapy remains poorly understood, particularly in high-grade serous tubo-ovarian carcinomas (HGSC). We developed a series ... -
Overcoming Scarcities Through Innovation: What Do Technologists Do When Faced With Constraints?
<p>The question that still divides many debates about sustainability is the possibility of technological substitution of scarce natural resources. While there is considerable debate among economists whether technology can ... -
Validation of IMPROD biparametric MRI in men with clinically suspected prostate cancer: A prospective multi-institutional trial
<p>Background: Magnetic resonance imaging (MRI) combined with targeted biopsy (TB) is increasingly used in men with clinically suspected prostate cancer (PCa), but the long acquisition times, high costs, and inter-center/reader ... -
Disparities in children's family experiences by mother's education: The case of Finland
<p>A well-known argument claims that socioeconomic differentials in children’s family structures have become increasingly important in shaping child outcomes and the resources available to children in developed societies. ... -
Comparison of ethanol tolerance between potential cyanobacterial production hosts
Cyanobacteria are photosynthetic prokaryotes that have been extensively studied as potential autotrophic biotechnological hosts for the production of different carbon-based end-products directly from atmospheric CO2. While ... -
Surgically treated ovarian lesions in preadolescent girls
Introduction The purpose of this study was to investigate the epidemiology and characteristics of surgically treated ovarian lesions in preadolescent girls. Material and methods This was a retrospective cohort study including ... -
Lubinuksen puoliproteesin komplikaatiot akuutin reisiluun kaulan murtuman hoidossa Keski-Suomen keskussairaalassa
<p>A total of 250 acute femoral neck fractures (244 patients) were operated using cemented<br />unipolar hemiarthroplasty (Lubinus sp II) in Central Finland Hospital, Jyväskylä<br />between 2007–2008. We retrospectively ... -
ILO:n uusi sopimus työväkivallasta
<p>Kansainvälinen työjärjestö (ILO) hyväksyi 21. kesäkuuta 2019 yleissopimuksen nro 190 väkivallan ja häirinnän poistamiseksi työelämässä sekä siihen liittyvän suosituksen nro 206. Sopimus ja Suositus ovat ensimmäiset ... -
Musiikkityöläisten elektroninen puutarha. Kraftwerk-yhtyeen Kling Klang -studio myöhäismodernina utopiana.
<p>Tässä artikkelissa tutkin ja tulkitsen Kraftwerk-yhtyeen studiokonseptia, sen muotoutumista ja kehitystä suhteessa yhtyeen itsensä rakentamaan ja ilmaisemaan käsitykseen Kling Klang -studiosta ”elektronisena puutarhana”. ... -
Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis
Objective: Obesity is the result of positive energy balance. It can be caused by excessive energy consumption but also by decreased energy dissipation, which occurs under several conditions including when the development ... -
In vitro Targetability Validation of Peptide-Functionalized Mesoporous Silica Nanoparticles in the Presence of Serum Proteins
Demonstration of receptor-mediated targeting of nanoparticles to specific organs and/or cell types is an integral aim in many bionanomedicine development projects. However, engagement of targeted receptors with ligands on ... -
User continuance intention toward theme park apps: a uses and gratification perspective
<p> Theme park apps are quickly becoming ubiquitous in the theme park industry. Understanding the factors that explain users’ continuance intention of theme park apps has attracted considerable attention from researchers ...
