dc.contributor.author | Kytö Ville | |
dc.contributor.author | Posti Jussi P. | |
dc.contributor.author | Rautava Paivi | |
dc.contributor.author | Luoto Teemu M. | |
dc.contributor.author | Sipilä Jussi O. T. | |
dc.date.accessioned | 2022-10-28T14:08:43Z | |
dc.date.available | 2022-10-28T14:08:43Z | |
dc.identifier.uri | https://www.utupub.fi/handle/10024/169627 | |
dc.description.abstract | Chronic subdural hematoma (cSDH), previously considered fairly benign and easy to treat, is now viewed a possible sign of incipient clinical decline. We investigated case-fatality, excess fatality and need for reoperations following operated cSDH in a nationwide setting focusing on patient-related characteristics. Finnish nationwide databases were searched for all admissions with operated cSDH as well as later deaths in adults (>= 16 years) during 2004-2017. There were 8539 patients with an evacuated cSDH (68% men) with a mean age of 73.0 (+/- 12.8) years. During the follow-up, 3805 (45%) patients died. In-hospital case-fatality was 0.7% (n = 60) and 30-day case-fatality 4.2% (n = 358). The 1-year case-fatality was 14.3% (95% CI = 13.4-15.2%) among men and 15.3% (95% CI = 14.0-16.7%) among women. Comorbidity burden, older age, and alcoholism were significantly associated with fatality. One-year excess fatality rate compared to general Finnish population was 9.1% (95% CI = 8.4-9.9) among men and 10.3% (95% CI = 9.1-11.4) among women. Highest excess fatality was observed in the oldest age group in both genders. Reoperation was needed in 19.4% (n = 1588) of patients. Older age but not comorbidity burden or other patient-related characteristics were associated with increased risk for reoperation. The overall case-fatality and need for reoperations declined during the study era. Comorbidities should be considered when care and follow-up are planned in patients with cSDH. Our findings underpin the perception that the disease is more dangerous than previously thought and causes mortality in all exposed age groups: even a minor burden of comorbidities can be fatal in the post-operative period. | |
dc.language.iso | en | |
dc.publisher | NATURE PORTFOLIO | |
dc.title | Prognosis of patients with operated chronic subdural hematoma | |
dc.identifier.url | https://www.nature.com/articles/s41598-022-10992-5 | |
dc.identifier.urn | URN:NBN:fi-fe2022081154844 | |
dc.relation.volume | 12 | |
dc.contributor.organization | fi=sydäntutkimuskeskus|en=Research Centre of Applied and Preventive Cardiovascular Medicine (CAPC)| | |
dc.contributor.organization | fi=sisätautioppi|en=Internal Medicine| | |
dc.contributor.organization | fi=tyks, vsshp|en=tyks, vsshp| | |
dc.contributor.organization | fi=kliinisen laitoksen yhteiset|en=Department of Clinical Medicine| | |
dc.contributor.organization | fi=väestötutkimuskeskus|en=Centre for Population Health Research (POP Centre)| | |
dc.contributor.organization | fi=kansanterveystiede|en=Public Health| | |
dc.contributor.organization | fi=kliiniset neurotieteet|en=Clinical Neurosciences| | |
dc.contributor.organization-code | 2607318 | |
dc.contributor.organization-code | 2607300 | |
dc.contributor.organization-code | 2607008 | |
dc.contributor.organization-code | 2607307 | |
dc.contributor.organization-code | 2607004 | |
dc.contributor.organization-code | 2607314 | |
dc.converis.publication-id | 175466633 | |
dc.converis.url | https://research.utu.fi/converis/portal/Publication/175466633 | |
dc.identifier.eissn | 2045-2322 | |
dc.identifier.jour-issn | 2045-2322 | |
dc.okm.affiliatedauthor | Posti, Jussi | |
dc.okm.affiliatedauthor | Kytö, Ville | |
dc.okm.affiliatedauthor | Dataimport, tyks, vsshp | |
dc.okm.affiliatedauthor | Sipilä, Jussi | |
dc.okm.affiliatedauthor | Rautava, Päivi | |
dc.okm.discipline | 3141 Health care science | en_GB |
dc.okm.discipline | 3121 Internal medicine | en_GB |
dc.okm.discipline | 3121 Sisätaudit | fi_FI |
dc.okm.discipline | 3141 Terveystiede | fi_FI |
dc.okm.internationalcopublication | not an international co-publication | |
dc.okm.internationality | International publication | |
dc.okm.type | Journal article | |
dc.publisher.country | United Kingdom | en_GB |
dc.publisher.country | Britannia | fi_FI |
dc.publisher.country-code | GB | |
dc.relation.articlenumber | 7020 | |
dc.relation.doi | 10.1038/s41598-022-10992-5 | |
dc.relation.ispartofjournal | Scientific Reports | |
dc.relation.issue | 1 | |
dc.year.issued | 2022 | |