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Stromal interaction molecule 1 and its role in the regulation, proliferation and protein expression in follicular ML-1 thyroid cancer cells
(Turun yliopisto, 2015-10-23)
Calcium (Ca2+) is involved in the regulation of variety of cellular functions including hallmarks of cancer development such as cellular migration and cellular proliferation. Store-operated calcium entry (SOCE) is a central ...
Ultrastructural changes of Fusobacterium nucleatum as a defense mechanism against human neutrophil peptide-1 - A Transmission Electron Microscopy (TEM) study
(Turun yliopisto, 2015-10-23)
Aims: The aim of this work was to assess the ultrastructural changes, cellular proliferation, and the biofilm formation ability of F. nucleatum as defense mechanisms against the effect of HNP-1. Materials and methods: The ...
Developing correlative Optical-Photoacustic microscopy for high-resolution in vivo imaging
(Turun yliopisto, 2015-10-23)
PhotoAcoustic Imaging (PAI) is a branch in clinical and pre-clinical imaging, that refers to the techniques mapping acoustic signals caused by the absorption of the short laser pulse. This conversion of electromagnetic ...
Effect of bariatric surgery on adipose tissue distribution in severely obese patients
(Turun yliopisto, 2015-10-23)
Background and aim: Bariatric surgery leads to sustain weight loss, improve metabolic and lipids profiles and ultimately leads to remission of type 2 diabetes (T2DM) in some obese individuals. The aim of the project is to ...
Imaging and target screening for novel avenues for psychiatric disorder treatments
(2020-02-18)
The JNK pathway is linked to both schizophrenia and depression but its impact is still being investigated. Zebrafish larvae at 7 days post-fertilization, were monitored for evoked motility changes after exposure to a variety ...
Mechanistic study of JNK inhibition in the context of depression
(2019-10-10)
Study 1:
Anxiety and depression disorders are the largest contributor for global disability and affects 4% of the world population. The patient remission rate is only 30-40% with single anti-depressant treatment, leaving ...
Association between intrathoracic adipose tissue mass and metabolic parameters
(Turun yliopisto, 2018-05-30)
Overweight or obesity, along with type 2 diabetes mellitus, is one of the major causes of cardiovascular morbidity and mortality. In the heart, fat is deposited inside – myocardial triglyceride content, and outside the ...
Association between intrathoracic adipose tissue mass and metabolic parameters
(Turun yliopisto, 2018-05-30)
Overweight or obesity, along with type 2 diabetes mellitus, is one of the major causes of cardiovascular morbidity and mortality. In the heart, fat is deposited inside – myocardial triglyceride content, and outside the ...
JNK regulation of nerve cell calcium : a possible mechanism in psychiatric disease
(2019-03-27)
Psychiatric disorders are a big problem in the modern world. The symptoms of these diseases vary, but common for all of them is that they are overpowering, consistent, and hamper daily life. Even though many treatments are ...
Exercise and brown adipose tissue activation in humans
(Turun yliopisto, 2016-06-08)