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Stromal interaction molecule 1 and its role in the regulation, proliferation and protein expression in follicular ML-1 thyroid cancer cells
(Turun yliopisto, 2015-10-23)
Calcium (Ca2+) is involved in the regulation of variety of cellular functions including hallmarks of cancer development such as cellular migration and cellular proliferation. Store-operated calcium entry (SOCE) is a central ...
Ultrastructural changes of Fusobacterium nucleatum as a defense mechanism against human neutrophil peptide-1 - A Transmission Electron Microscopy (TEM) study
(Turun yliopisto, 2015-10-23)
Aims: The aim of this work was to assess the ultrastructural changes, cellular proliferation, and the biofilm formation ability of F. nucleatum as defense mechanisms against the effect of HNP-1. Materials and methods: The ...
PTEN-geenin puuttumisen vaikutuksen arviointi eturauhassyövän esiasteisiin hiirimallissa
(Turun yliopisto, 2015-10-30)
Luukudoksen ja elimistön energiametabolian yhteys
(Turun yliopisto, 2016-02-18)
Paljonko on tarpeeksi? Roflumilastin kliinisen kehitysvaiheen tutkimukset
(Turun yliopisto, 2015-09-18)
New functions for the cellular oxygen sensor PHD3 in clear cell renal cell carcinoma
(Turun yliopisto, 2018-05-18)
The family of HIF prolyl hydroxylase enzymes (PHDs) is known for their function of post-translationally regulating hypoxia-inducible transcription factors (HIFs) in oxygen-dependent manner. HIFs are the key transcription ...
Fibroblast growth factor receptors and their inhibitors in preclinical models of breast cancer and bone metastasis
(Turun yliopisto, 2019-11-29)
Advanced, metastatic stages of breast cancer are associated with high morbidity and mortality, and there is a need to establish a proof-of-concept for novel compounds that can change this scheme. Fibroblast growth factors ...
Effect of melanocortin-1 receptor in the regulation of beta3-adrenoceptor agonist-induced BAT thermogenesis
(Turun yliopisto, 2019-03-01)
Adipose tissue is comprised of brown and white adipose tissues. In particular, brown adipose tissues (BAT) or brown fat contain rich amount of beta3-adrenoceptors (β3AR) and they are regulated by sympathetic nervous system ...
Vascular adhesion protein-1, its ligands and role in cardiovascular disease prediction
(Turun yliopisto, 2018-09-21)
To study the pathogenesis and prevention of diseases, population studies in which hundreds of measurements are done from the same persons have a crucial role. A biomarker is any measurable characteristic that gives information ...