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Aineistot 1-10 / 151
Aminophenolato complexes of Mo, W and V In catalytic alkene epoxidation and catechol oxidation
(Turun yliopisto, 2021-11-05)
Mo, W and V are found naturally in metalloenzymes such as the Mo/W oxotransferases and the V haloperoxidases (VHPOs). These enzymes catalyze oxidation reactions related to C, N, S metabolism as well as halogenation. Cu and ...
Photoluminescence quenchers in drug discovery
(Turun yliopisto, 2021-12-03)
During the drug discovery process molecular libraries containing millions of molecules are screened to find a single potential drug with the highest potency and efficacy over unwanted side-effects. The whole drug development ...
Synthesis and Characterization of New Composite Materials for Cathodes in Batteries
(2022-09-13)
Over the past decades, the revolution of lithium-ion batteries (LIBs) has been conquering the energy
storage market in a tremendous rate. Due to their high-power output and superior energy density,
LIBs have been used ...
Controlled Decoration of Molecular Spherical Nucleic Acids
(Turun yliopisto, 2022-10-31)
Research on therapeutically effective oligonucleotides (antisense oligonucleotides, ASOs and small interfering RNAs, siRNAs) has grown rapidly during the last decades. Oligonucleotide (ON) therapeutics are nowadays an ...
Highlighting the chemical diversity of plants: modern tools for chemistry education
(Turun yliopisto, 2022-10-28)
The chemical diversity of plants is enormous as plants produce a variety of compounds that play key roles, for instance, in the growth, defence and reproduction of plants. This diversity is not well recognised in chemistry ...
Rakenteen vaikutus hydrolysoituvien tanniinien stabiilisuuteen fysiologisissa olosuhteissa
(2022-09-30)
Tanniinit ovat polyfenoleja, jotka perinteisen määritelmänsä mukaan kykenevät saostamaan vesiliuoksissa proteiineja ja muita makromolekyylejä. Tanniineilla on tunnetusti havaittu paljon hyödyllisiä ominaisuuksia ihmisille ...
Star Polymer–Protein Conjugates to Study Movement of Proteins in Bacterial Cell Membranes
(2022-09-28)
Antibiotic resistance in bacteria is a rapidly growing issue worldwide. Especially, a lack of efficient antibiotics against Gram-negative bacteria is a problem since they have an outer membrane that provides additional ...
15N-Leimattujen palladasyklisten oligonukleotidien synteesi ja hybridisaatio
(2022-08-30)
Usein luonnolliset nukleiinihapot on muokattava terapeuttiseen tarkoitukseen ja yksi vaihtoehto on metalli-ionivälitteinen emäspariutuminen, jossa keskusmetalli-ioni on sitoutunut nukleoemästen väliin luonnollisten ...
Expression, purification and characterization of recombinant RNA-dependent RNA polymerase from Heterobasidion RNA virus 6
(2022-05-09)
RNA-dependent RNA polymerases (RdRps) are enzymes that catalyze nucleotide polymerization on RNA template in the presence of divalent metal ions. These enzymes are central for the life cycle of viruses with RNA genomes. A ...
Aineenvaihduntatuotteiden automaattinen kvantitointi virtsasta
(2022-04-28)
Aineenvaihduntatuotteet kertovat paljon yksilön terveydentilasta ja niiden avulla on mahdollista tehdä riskiarvioita yksilöstä, kunhan populaatiotason vertailuarvot ovat tunnettuja. Aineenvaihduntatuotteiden laaja mittaaminen ...