Hae
Aineistot 1-10 / 41
Rasva-aineenvaihdunta poikkijuovaisissa lihaksissa
(Turun yliopisto, 2017-11-28)
Development of male reproductive health in puberty and young adulthood
(Turun yliopisto, 2018-11-30)
The deterioration of male reproductive health is a worrying global trend in respect to the individual fertility of the man. Modern knowledge suggests the etiological role for early testicular damage and harmful effects of ...
MicroRNA-mediated regulation of mitosis and taxane sensitivity in breast and ovarian cancer
(Turun yliopisto, 2017-11-24)
Taxanes are microtubule targeting chemotherapeutics that block cell division (mitosis) and induce cell death. Taxanes are commonly used in the neoadjuvant chemotherapy for breast and ovarian cancer. However, the patient ...
The effect of training background on oxidized lipoprotein lipids and antioxidant capacity in athletes and keep-fit runners
(Turun yliopisto, 2018-12-07)
Background: High-intensity acute exercise is known to induce oxidative stress and may lead to harmful oxidation of lipids, and protein and DNA damage. On the other hand, exercise is known to positively influence risk factors ...
ANDROGEN SIGNALING AXIS AS DRUG TARGET IN CASTRATION-RESISTANT PROSTATE CANCER: Preclinical development of novel treatments and models
(Turun yliopisto, 2018-06-15)
Abstract:
Prostate cancer is a major global challenge due to the increasing number of aging population
and frequency of diagnosis. Already in 1941, Huggins and Hodges showed that metastatic
prostate cancer is responsive ...
Verenkierto, hengitys ja nestetasapaino -kurssin oppimateriaalityö : Lämpötasapaino
(Turun yliopisto, 2017-11-01)
Hydroxysteroid (17beta) dehydrogenase 1 expression enhances estrogen action and serves as a potential drug target for reducing estrogen signaling in the uterus and mammary glands
(Turun yliopisto, 2018-01-26)
Hydroxysteroid (17beta) dehydrogenase type 1 (HSD17B1) is a steroidmetabolizing enzyme with a preface for converting the low active estrogen estrone (E1) to highly active estradiol (E2). Accordingly, HSD17B1 is expressed ...
The effects of PFOA (perfluorooctanoic acid) on fetal and adult rat testis
(2019-02-27)
Perfluorooctanoic acid (PFOA) is a widely dispersed synthetic chemical, which accumulates in living organisms and has been connected with male reproductive disorders. To monitor the effects of PFOA, fetal rat testes or ...
Regulation of human aromatase gene expression in adipose tissue
(2020-02-29)
The conversion of androgens to estrogens is catalyzed by the aromatase enzyme, the product of the CYP19A1 gene, in gonads and peripheral tissues. Estrogens produced in the white adipose tissue (WAT) are postulated to play ...
Regulation of gonadal steroid synthesis and reproduction : novel roles of hydroxysteroid (17β) dehydrogenase 1
(Turun yliopisto, 2017-12-15)
Estrogens and androgens are critical regulators of several physiological processes,including development and reproduction. In addition, these hormones play key roles in several physiological complications and diseases, ...