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Aineistot 21-30 / 115
Analysis of GNAT gene expression in Arabidopsis thaliana
(2022-07-01)
In Arabidopsis thaliana (Arabidopsis), chloroplast localized GCN5 related N acetyltransferases (GNATs) are active acetyltransferase enzymes catalyzing two distinct acetylation reactions, i.e., N terminal and lysine acetylation ...
Dried blood spot immunoassay for the detection of pre-eclampsia in developing countries
(2022-03-17)
Ninety-nine percent of deaths caused by pre-eclampsia occur in developing countries. The disorder can easily be treated if detected early enough. Traditionally diagnosis is made using maternal characteristics and medical ...
Non-invasiivisen prenataaliseulonnan toiminnallisuuden kehittäminen
(2022-06-08)
Sikiön kehityksen aikana kromosomisto voi kehittyä virheellisesti, joka johtaa poikkeavaan kromosomimäärään. Poikkeavuudet aiheuttavat sikiölle ominaisuuksia, joista osa voi olla sikiölle hengenvaarallisia. Tässä työssä ...
Development of dual immunoassay for detection of mitochondrial disorders
(2021-01-28)
Mitochondrial disorders (MDs) are a large group of disorders that manifest with a wide variety of different symptoms. In addition, the lack of both sensitive and specific non-invasive biomarkers has made the detection of ...
Design and evaluation of the CRISPR-Cas9 genome editing approach in hippocampal neurons for defining neurodegenerative mechanisms in Parkinson's disease
(2021-08-04)
Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder. In order to improve diagnostic and therapeutic approaches for PD, disease etiology needs to be better understood. Advances in gene editing ...
Long-acting silica formulations - In vitro study of inflammatory response in the eye
(2021-10-18)
Inflammation is body’s typical response to unnatural, pathogenic events occurring inside the individual. In the eye, inflammation is a critical condition which can lead to sever problems, including permanent loss of vision. ...
Inhibitory effects of SARS-CoV-2 nonstructural proteins on the RIG-I signaling pathway
(2021-10-18)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) from the Coronaviridae family is an enveloped, spherical virus with a 30 kb long non-segmented positive single-stranded RNA genome, which encodes for 16 ...
ELISA-menetelmien hyödyntäminen kosteusvaurioiden aiheuttamien immunologisten vasteiden tutkimuksessa
(2021-11-05)
Suuressa osassa rakennuksia ilmenee jossain niiden elinkaaren aikana kosteusvaurioita, joissa usein havaitaan mikrobikasvustoa. Kuivuessa mikrobipartikkelit saattavat emittoitua kasvustosta sisäilmaan ja dormantit partikkelit ...
Developing and optimizing microfluidics platform for fabricating lignin nanoparticles.
(2021-01-21)
Introduction: Lignin is a complex organic polymer, produced in large quantities as a by-product from pulp and paper industries. Despite of large-scale production, lignin is not being utilized for high value applications. ...
Selection, screening and testing of recombinant Fabs against mutated amyloidogenic gelsolin peptide : the causative agent of hereditary gelsolin amyloidosis
(2021-05-06)
Extracellular gelsolin is an actin modulating plasma protein that is abnormally digested, due to an amino acid substitution, into amyloidogenic 8 kDa peptides (AGel), the causative agents of hereditary gelsolin ...