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Aineistot 21-26 / 26
CD73 as a prognostic biomarker in human pancreatic cancer
(2021-02-01)
Cell surface protein CD73 has important role in sustaining immune homeostasis as the key regulator of extracellular adenosine which mediates immunosuppression and angiogenesis. This CD73 regulated pathway is shown to promote ...
The role of PLVAP protein in endothelial cells of liver
(2021-02-09)
In endothelial cells (EC) PLVAP protein forms permeability regulating structures known as diaphragms. In some previous studies it has been stated that PLVAP does not exist in adult liver ECs, because diaphragms of liver ...
ORIGINS OF ANTIBODY DIVERSITY AND THE ROLE OF BACH2 IN SOMATIC HYPERMUTATION
(2021-03-16)
Antibodies produced by B cells are critical for our immunological defence against pathogens. For antibodies, the ability to recognise and bind pathogenic antigens improves through time during infection. Improvement is due ...
Lymph-derived soluble Clever-1 : Effect on cancer cell viability
(2023-03-02)
Cancer is one of the most important causes of premature death. Even though the treatment of cancer has seen considerable advancements in the past decades, there are still numerous cancers without effective treatment. ...
Synnytys- ja lapsivuodeajan infektiot ja niiden mikrobietiologia Varhan alueella vuosina 2013–2022
(2024-03-26)
Lapsivuodeaika tarkoittaa 6–8 synnytyksenjälkeistä viikkoa, jolloin äidin elimistö palaa raskautta edeltäneeseen tilaan. Lapsivuodeajan infektiot ovat merkittävä äidin ja vastasyntyneen sairastavuuden ja kuolleisuuden ...
CD47 and TREM2 for macrophage-targeted cancer immunotherapy: Antibody validation and ex vivo efficacy in patient-derived explant cultures
(2024-03-13)
Cancer remains a common cause of death worldwide. Cancer cells develop several mechanisms to escape immune destruction, which limits the efficacy of current treatments and creates a need for new therapies. Cancer immunotherapies ...