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Aineistot 21-28 / 28
Re-educating macrophages to activate antitumor immunity: One Clever Immunotherapy
(Turun yliopisto, 2023-04-14)
The immune system is our constant protector against external foes but also against our own incipient malignant cells. Unfortunately, developing cancers often learn to shut down the antitumor immune response or even to ...
The Gut-pancreas axis in autoimmune diabetes
(Turun yliopisto, 2023-05-12)
The gut microbiota has been suggested to be an important factor in the development of autoimmune diseases such as type 1 diabetes (T1D). Priming of islet specific T cells in the pancreatic lymph nodes (PaLN) and their ...
Molecular surveillance of carbapenemase-producing Enterobacterales in Finland
(Turun yliopisto, 2023-04-12)
Carbapenemase-producing (CP) Enterobacterales (CPE) are a growing menace to healthcare systems worldwide. CPE infections are difficult to treat because few antimicrobials remain effective. One of the new drug combinations, ...
Immunological mechanisms in the pathogenesis of type 1 diabetes
(Turun yliopisto, 2023-06-06)
Type 1 diabetes is a chronic autoimmune disease, in which insulin secreting beta cells in the pancreas are destroyed. The disease pathogenesis can be divided into an asymptomatic preclinical phase and symptomatic disease. ...
Interrelations between microbiota, metabolism and low-grade inflammation with obesity and gestational diabetes mellitus: Means to intervene during pregnancy
(Turun yliopisto, 2023-06-30)
ABSTRACT
Pregnant women with overweight and obesity may exhibit altered circulating lowgrade inflammatory and metabolic profile and gut and vaginal microbiota which may contribute to the development of gestational ...
Foetal monocytes and their journey from liver to periphery: PLVAP marks the exit
(Turun yliopisto, 2023-10-24)
ABSTRACT
Endothelium is the barrier between the blood and tissue stroma. Cells and macromolecules are selectively allowed to traffic through the endothelium to maintain homeostasis. Besides the paracellular transport ...
Ontogeny and function of adipose tissue macrophages
(Turun yliopisto, 2023-11-03)
ABSTRACT
Macrophages are immune cells that also participate in the development and homeostasis of most tissues. Macrophages can originate during embryonic development, first from the yolk sac and later from the fetal ...
Characteristics of anti-pertussis toxin antibodies after vaccination and infection
(Turun yliopisto, 2024-04-12)
Pertussis or whooping cough is a human respiratory tract infection caused by Bordetella pertussis bacteria. Despite extensive vaccinations, pertussis incidence has increased during the last decades. The reasons behind this ...