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Aineistot 41-50 / 65
Vipera berus bites in Finlad – has anything changed during the last decade?
(2023-02-19)
The common European adder, Vipera berus, is the only indigenous venomous snake in
Finland. Dozens of snakebites happen every year and most patients experience only
local symptoms, but the possibility of severe complications ...
Opiskelijalähtöiset kertaustehtävät farmakologian itseopiskelun tukena
(2023-08-29)
Turun yliopistossa suoritetaan lääketieteen opintojen 2. vuoden keväällä Farmakologia-opintojakso, jonka osaamistavoitteisiin kuuluvat muun muassa perusterveydenhuollossa käytettävien lääkkeiden vaikutusmekanismit, ...
S1A-proteaasin rooli verisolujen aktivaatiossa Drosophila melanogaster -banaanikärpäsellä
(2025-04-09)
Synnynnäisen immuniteetin tutkimuksessa hyödynnetään laajasti Drosophila melanogaster -banaanikärpäsmallia, sillä D. melanogaster -lajin synnynnäinen immuniteetti on hyvin konservoitunut, ja adaptiivinen immuniteetti niiltä ...
Uudet lääkkeet metabolisen rasvamaksataudin hoidossa
(2025-06-16)
Metabolinen rasvamaksatauti on yleisin krooninen maksasairaus sekä merkittävä maksaperäisen kuolleisuuden aiheuttaja länsimaissa, ja sen ilmaantuvuus on kasvussa. Metabolinen rasvamaksatauti kattaa tautikirjon rasvamaksasta ...
Cellular regulation of the norepinephrine transporter
(Turun yliopisto, 2018-02-23)
The norepinephrine (NE) transporter (NET) mediates high-affinity uptake of the neurotransmitter NE in central and peripheral noradrenergic neurons. NET has a critical function in controlling the synaptic levels of NE and ...
The Role of maternal prenatal distress in the development and functioning of the infant cortisol stress response
(Turun yliopisto, 2022-01-21)
The adrenal cortex secretes cortisol during stressful situations to regulate stress reactions of several other systems, such as the immune system, to enhance coping and survival. An altered cortisol stress responsiveness ...
Molecular dynamics and virtual screening approaches in drug discovery
(Turun yliopisto, 2022-10-28)
Computer-aided drug discovery (CADD) methods are now routinely used in the
preclinical phase of drug development. Powerful high-performance computing
facilities and the extremely fast CADD methods constantly scale up the ...
The role of melanocortin-1 and -3 receptors in inflammation and atherosclerosis
(Turun yliopisto, 2023-04-28)
The melanocortin system comprises the endogenous melanocortin peptides adrenocorticotropic hormone (ACTH) and melanocyte-stimulating hormones (α-, β- & γ-MSH) as well as their five cognate receptors (MC1R – MC5R). These ...
Calcium signaling and neuropeptide Y in experimental models of heart failure
(Turun yliopisto, 2020-11-13)
Despite advances in medical therapy and interventional procedures, heart failure carries a dismal prognosis. Calcium has a central role in controlling the contractility of the heart, and the sarcoplasmic reticulum Ca2+ ...
Premature ejaculation - potential role of α2-adrenoceptor agonists for symptomatic treatment. Studies of dexmedetomidine, fadolmidine and tasipimidine
(Turun yliopisto, 2024-04-26)
Ejaculation is a physiological process that results in the expulsion of semen from the male reproduction tract during a sexual climax and is considered an essential component of natural conception. Ejaculation is a delicately ...