Adventures in radiosynthesis of clinical grade [68Ga]Ga-DOTA-Siglec-9

Toimittaja(t)

ROYAL SOC CHEMISTRY
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c7ra12423f.pdf - 588.46 KB
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Pysyvä osoite

https://urn.fi/URN:NBN:fi-fe2021042718943

Verkkojulkaisu

DOI

10.1039/c7ra12423f

Tiivistelmä

We finally managed to establish a protocol for generating Good Manufacturing Practice (GMP)-grade gallium-68-labelled 1,4,7,0-tetraazacyclododecane-1,4,7,10-tetraacetic acid conjugated sialic acid-binding immunoglobulin-like lectin 9 motif containing peptide ([Ga-68]Ga-DOTA-Siglec-9), the first radiopharmaceutical for positron emission tomography imaging of vascular adhesion protein 1.

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