Adventures in radiosynthesis of clinical grade [68Ga]Ga-DOTA-Siglec-9

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dc.contributor.authorKäkelä Meeri
dc.contributor.authorLuoto Pauliina
dc.contributor.authorViljanen Tapio
dc.contributor.authorVirtanen Helena
dc.contributor.authorLiljenbäck Heidi
dc.contributor.authorJalkanen Sirpa
dc.contributor.authorKnuuti Juhani
dc.contributor.authorRoivainen Anne
dc.contributor.authorLi Xiang-Guo
dc.contributor.organizationfi=MediCity|en=MediCity|
dc.contributor.organizationfi=PET-keskus|en=Turku PET Centre|
dc.contributor.organizationfi=biolääketieteen laitos|en=Institute of Biomedicine|
dc.contributor.organizationfi=lääkekehityksen kemia|en=Pharmaseutical Chemistry|
dc.contributor.organizationfi=tyks, vsshp|en=tyks, varha|
dc.contributor.organization-code1.2.246.10.2458963.20.14646305228
dc.contributor.organization-code1.2.246.10.2458963.20.77952289591
dc.contributor.organization-code1.2.246.10.2458963.20.83772236069
dc.contributor.organization-code1.2.246.10.2458963.20.93793350823
dc.contributor.organization-code2609810
dc.converis.publication-id30431180
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/30431180
dc.date.accessioned2022-10-28T13:46:39Z
dc.date.available2022-10-28T13:46:39Z
dc.description.abstractWe finally managed to establish a protocol for generating Good Manufacturing Practice (GMP)-grade gallium-68-labelled 1,4,7,0-tetraazacyclododecane-1,4,7,10-tetraacetic acid conjugated sialic acid-binding immunoglobulin-like lectin 9 motif containing peptide ([Ga-68]Ga-DOTA-Siglec-9), the first radiopharmaceutical for positron emission tomography imaging of vascular adhesion protein 1.
dc.format.pagerange8051
dc.format.pagerange8056
dc.identifier.eissn2046-2069
dc.identifier.olddbid184246
dc.identifier.oldhandle10024/167340
dc.identifier.urihttps://www.utupub.fi/handle/11111/41730
dc.identifier.urnURN:NBN:fi-fe2021042718943
dc.language.isoen
dc.okm.affiliatedauthorKäkelä, Meeri
dc.okm.affiliatedauthorLuoto, Pauliina
dc.okm.affiliatedauthorViljanen, Tapio
dc.okm.affiliatedauthorVirtanen, Helena
dc.okm.affiliatedauthorLiljenbäck, Heidi
dc.okm.affiliatedauthorJalkanen, Sirpa
dc.okm.affiliatedauthorKnuuti, Juhani
dc.okm.affiliatedauthorRoivainen, Anne
dc.okm.affiliatedauthorLi, Xiang-Guo
dc.okm.affiliatedauthorDataimport, tyks, vsshp
dc.okm.discipline116 Chemical sciencesen_GB
dc.okm.discipline116 Kemiafi_FI
dc.okm.internationalcopublicationnot an international co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherROYAL SOC CHEMISTRY
dc.publisher.countryUnited Kingdomen_GB
dc.publisher.countryBritanniafi_FI
dc.publisher.country-codeGB
dc.relation.doi10.1039/c7ra12423f
dc.relation.ispartofjournalRSC Advances
dc.relation.issue15
dc.relation.volume8
dc.source.identifierhttps://www.utupub.fi/handle/10024/167340
dc.titleAdventures in radiosynthesis of clinical grade [68Ga]Ga-DOTA-Siglec-9
dc.year.issued2018

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