Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

Toimittaja(t)

BIOMED CENTRAL LTD
A35Santio2010.pdf
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Pysyvä osoite

https://urn.fi/URN:NBN:fi-fe2021042714234

Verkkojulkaisu

DOI

10.1186/1476-4598-9-279

Tiivistelmä

Conclusions: Altogether, our data indicate that DHPCC-9 is not only a powerful tool to investigate physiological effects of the oncogenic Pim family kinases, but also an attractive molecule for drug development to inhibit invasiveness of Pim-overexpressing cancer cells.

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