Pim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion

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dc.contributor.authorSantio NM
dc.contributor.authorVahakoski RL
dc.contributor.authorRainio EM
dc.contributor.authorSandholm JA
dc.contributor.authorVirtanen SS
dc.contributor.authorPrudhomme M
dc.contributor.authorAnizon F
dc.contributor.authorMoreau P
dc.contributor.authorKoskinen PJ
dc.contributor.organizationfi=BioCity Turku|en=BioCity Turku|
dc.contributor.organizationfi=Turun biotiedekeskus|en=Turku Bioscience Centre|
dc.contributor.organizationfi=biologian laitos|en=Department of Biology|
dc.contributor.organizationfi=fysiologia ja genetiikka|en=Physiology and Genetics|
dc.contributor.organizationfi=lääketieteellinen tiedekunta|en=Faculty of Medicine|
dc.contributor.organizationfi=solubiologia ja anatomia|en=Cell Biology and Anatomy|
dc.contributor.organization-code1.2.246.10.2458963.20.13290506867
dc.contributor.organization-code1.2.246.10.2458963.20.18586209670
dc.contributor.organization-code1.2.246.10.2458963.20.70712835001
dc.contributor.organization-code1.2.246.10.2458963.20.77193996913
dc.contributor.organization-code2606400
dc.contributor.organization-code2607101
dc.contributor.organization-code2609260
dc.converis.publication-id1643758
dc.converis.urlhttps://research.utu.fi/converis/portal/Publication/1643758
dc.date.accessioned2022-10-27T12:18:53Z
dc.date.available2022-10-27T12:18:53Z
dc.description.abstractConclusions: Altogether, our data indicate that DHPCC-9 is not only a powerful tool to investigate physiological effects of the oncogenic Pim family kinases, but also an attractive molecule for drug development to inhibit invasiveness of Pim-overexpressing cancer cells.
dc.identifier.jour-issn1476-4598
dc.identifier.olddbid174674
dc.identifier.oldhandle10024/157768
dc.identifier.urihttps://www.utupub.fi/handle/11111/34661
dc.identifier.urnURN:NBN:fi-fe2021042714234
dc.language.isoen
dc.okm.affiliatedauthorSantio, Niina
dc.okm.affiliatedauthorVahakoski, Riitta
dc.okm.affiliatedauthorRainio, Eeva
dc.okm.affiliatedauthorSandholm, Jouko
dc.okm.affiliatedauthorVirtanen, Sanna
dc.okm.affiliatedauthorKoskinen, Päivi
dc.okm.affiliatedauthorDataimport, Biologian laitoksen yhteiset
dc.okm.discipline1182 Biochemistry, cell and molecular biologyen_GB
dc.okm.discipline3111 Biomedicineen_GB
dc.okm.discipline1182 Biokemia, solu- ja molekyylibiologiafi_FI
dc.okm.discipline3111 Biolääketieteetfi_FI
dc.okm.internationalcopublicationinternational co-publication
dc.okm.internationalityInternational publication
dc.okm.typeA1 ScientificArticle
dc.publisherBIOMED CENTRAL LTD
dc.publisher.countryUnited Kingdomen_GB
dc.publisher.countryBritanniafi_FI
dc.publisher.country-codeGB
dc.relation.articlenumberARTN 279
dc.relation.doi10.1186/1476-4598-9-279
dc.relation.ispartofjournalMolecular Cancer
dc.relation.volume9
dc.source.identifierhttps://www.utupub.fi/handle/10024/157768
dc.titlePim-selective inhibitor DHPCC-9 reveals Pim kinases as potent stimulators of cancer cell migration and invasion
dc.year.issued2010

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