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Aineistot 10661-10680 / 58417

    • Mortality Among Pediatric Patients With Acute Lymphoblastic Leukemia in Sweden From 1988 to 2017 

      Björk-Eriksson Thomas; Boström Martina; Bryngelsson Ing-Liss; Lähteenmäki Päivi M; Jarfelt Marianne; Kalm Marie; Olsson Daniel S
      <p><strong>Importance: </strong>Acute lymphoblastic leukemia (ALL) constitutes 20% to 30% of all pediatric cancers. The 5-year overall survival among pediatric patients with ALL in high-income countries such as Sweden is ...

    • Inferring Tree-Shaped Single-Cell Trajectories with Totem 

      Sousa, António GG; Smolander, Johannes; Junttila, Sini; Elo, Laura L.
      Methods in Molecular Biology
      <p>Single-cell transcriptomics allows unbiased characterization of cell heterogeneity in a sample by profiling gene expression at single-cell level. These profiles capture snapshots of transient or steady states in dynamic ...

    • Can visualization alleviate dichotomous thinking Effects of visual representations on the cliff effect 

      Helske Jouni; Helske Satu; Cooper Matthew; Ynnerman Anders; Besançon Lonni
      <p>Common reporting styles for statistical results in scientific articles, such as \pvalues\ and confidence intervals (CI), have been reported to be prone to dichotomous interpretations, especially with respect to the ...

    • Koettu yksinäisyys Suomessa 2016-2022 

      Laaninen Markus; Niemelä Mikko
      <p>Koronarajoitukset vähensivät ihmisten välistä kanssakäymistä, mikä on nostanut esiin huolen etenkin nuorten ja ikääntyneiden yksinäisyyden lisääntymisestä. Artikkelissa yksinäisyyden kokemusta tarkastellaan ennen ...

    • Safety and feasibility of endoscopic sinus surgery as an office-based procedure 

      Abrahamsson, Sebastian; Kolari, Terhi; Numminen, Jura; Irjala, Heikki
      <p>Background: The purpose of this study was to evaluate whether office-based endoscopic sinus surgery (ESS) is as safe as traditional outpatient surgery and whether there are differences in the operation results, patient ...

    • Upworkers in Finland: Survey Results 

      Pajarinen Mika; Rouvinen Petri; Claussen Jörg; Hakanen Jari; Kovalainen Anne; Kretschmer Tobias; Poutanen Seppo; Seifried Mareike; Seppänen Laura
      ETLA Raportit - Reports
      <p>Upwork is the world’s largest online labor market platform connecting clients with freelance professionals from various disciplines ranging from administrative support to web development. This study documents the main ...

    • The characteristics of leadership and their effectiveness in quality management in healthcare - A systematic literature review and a content analysis 

      Friman Susanna; Maijala Riikka; Eloranta Sini; Suominen Sakari; Ikonen Tuija
      Effective quality leadership is identified as a critical factor for organisational success. Leadership style has an important role in the implementation of quality management. This systematic review describes the characteristics ...

    • Developing Higher Education Pedagogy as a Pioneer 

      Murtonen Mari

    • Pleiotropic Effects of Secretin: A Potential Drug Candidate in the Treatment of Obesity? 

      Laurila Sanna; Rebelos Eleni; Honka Miikka-Juhani; Nuutila Pirjo
      <p>Secretin is the first hormone that has been discovered, inaugurating the era and the field of endocrinology. Despite the initial focus, the interest in its actions faded away over the decades. However, there is mounting ...

    • Cognitive authorities of COVID-19 information: educational differences and outcomes of trust in health experts and social media influencers in Finland 

      Malinen, Sanna; Koivula, Aki
      <p><span>Introduction</span><span>. This study investigates people’s trust in institutional healthcare </span><span>experts and social media influencers as sources of COVID</span><span>-19 information. Us</span><span>ing ...

    • Lähiön valoarvot 

      Leinonen Päivi
      <p>Tiederuno pohjautuu artikkeliin, jossa korostan, että estetisoiva katse ja havainnoille herkistyminen on voimavara ympäristön kokemista tutkittaessa. Valokuvahaastattelu tutkimusmenetelmänä paljastaa maisemasta sellaisia ...

    • Opioidikorvaushoidossa olevien määrä on jatkanut kasvuaan 

      Partanen Airi; Alho Hannu; Kuussaari Kristiina; Niemelä Solja; Partanen Markku; Rönkä Sanna; Sundqvist Lotta; Vorma Helena
      <p>Lähtökohdat : Tavoitteena oli saada tietoa opioidivieroitus- ja korvaushoidossa olleiden määrästä vuonna 2019. Vuonna 2017 opioidien ongelmakäyttäjiä arvioitiin olleen 23 500−29 500. <br></p><p>Menetelmät : Poikkileik ...

    • X-Ray Polarization of the Black Hole X-Ray Binary 4U 1630–47 Challenges the Standard Thin Accretion Disk Scenario 

      Ratheesh A; Dovčiak M; Krawczynski H; Podgorný J; Marra L; Veledina A; Suleimanov VF; Cavero NR; Steiner JF; Svoboda J; Marinucci A; Bianchi S; Negro M; Matt G; Tombesi F; Poutanen J; Ingram A; Taverna R; West A; Karas V; Ursini F; Soffitta P; Capitanio F; Viscolo D; Manfreda A; Muleri F; Parra M; Beheshtipour B; Chun S; Cibrario N; Lalla ND; Fabiani S; Hu K; Kaaret P; Loktev V; Mikušincová R; Mizuno T; Omodei N; Petrucci P; Puccetti S; Rankin J; Zane S; Zhang S; Agudo I; Antonelli LA; Bachetti M; Baldini L; Baumgartner WH; Bellazzini R; Bongiorno SD; Bonino R; Brez A; Bucciantini N; Castellano S; Cavazzuti E; Chen C; Ciprini S; Costa E; Rosa AD; Monte ED; Gesu LD; Marco AD; Donnarumma I; Doroshenko V; Ehlert SR; Enoto T; Evangelista Y; Ferrazzoli R; Garcia JA; Gunji S; Hayashida K; Heyl J; Iwakiri W; Jorstad SG; Kislat F; Kitaguchi T; Kolodziejczak JJ; Monaca FL; Latronico L; Liodakis I; Maldera S; Marin F; Marscher AP; Marshall HL; Massaro F; Mitsuishi I; Ng SC; O’Dell SL; Oppedisano C; Papitto A; Pavlov GG; Peirson AL; Perri M; Pesce-Rollins M; Pilia M; Possenti A; Ramsey BD; Roberts OJ; Romani RW; Sgrò C; Slane P; Spandre G; Swartz DA; Tamagawa T; Tavecchio F; Tawara Y; Tennant AF; Thomas NE; Trois A; Tsygankov SS; Turolla R; Vink J; Weisskopf MC; Wu K; Xie F
      A large energy-dependent X-ray polarization degree is detected by the Imaging X-ray Polarimetry Explorer (IXPE) in the high-soft emission state of the black hole X-ray binary 4U 1630–47. The highly significant detection ...

    • Efficacy and moderators of efficacy of cognitive behavioural therapies with a trauma focus in children and adolescents : an individual participant data meta-analysis of randomised trials 

      de Haan Anke; Meiser-Stedman Richard; Landolt Markus A; Kuhn Isla; Black Melissa J; Klaus Kristel; Patel Shivam D; Fisher David J; Haag Christina; Ukoumunne Obioha C; Jones Benjamin G; Flaiyah Ashraf Muwafaq; Catani Claudia; Dawson Katie; Bryant Richard A; de Roos Carlijn; Ertl Verena; Foa Edna B; Ford Julian D; Gilboa-Schechtman Eva; Tutus Dunja; Hermenau Katharin; Hecker Tobias; Hultmann Ole; Axberg Ulf; Jaberghaderi Nasrin; Jensen Tine K; Ormhaug Silje M; Kenardy Justin; Lindauer Ramon J L; Diehle Julia; Murray Laura K; Kane Jeremy C; Peltonen Kirsi; Kangaslampi Samuli; Robjant Katy; Koebach Anke; Rosner Rita; Rossouw Jaco; Smith Patrick; Tonge Bruce J; Hitchcock Caitlin; Dalgleish Tim
      <p>Background <br></p><p>Existing clinical trials of cognitive behavioural therapies with a trauma focus (CBTs-TF) are underpowered to examine key variables that might moderate treatment effects. We aimed to determine the ...

    • Parental morph combination does not influence innate immune function in nestlings of a colour-polymorphic African raptor 

      Nebel Carina; Amar Arjun; Hegemann Arne; Isaksson Caroline; Sumasgutner Petra
      Conditions experienced during early life can have long-term individual consequences by influencing dispersal, survival, recruitment and productivity. Resource allocation during development can have strong carry-over effects ...

    • Finnish paediatric study found a low incidence of bacterial meningitis from 2011 to 2018 but a substantial proportion of nosocomial meningitis 

      Niemelä Sakke; Lempinen Laura; Löyttyniemi Eliisa; Grönroos Juha O; Luoto Raakel; Peltola Ville; Jero Jussi
      <p><b>Aim</b></p><p>This study examined the predisposing factors, clinical picture, bacterial aetiology and clinical outcomes of infants and children with bacterial meningitis (BM).</p><p><b>Methods</b></p><p>The medical ...

    • Optimal sampling and analysis methods for clinical diagnostics of vaginal microbiome 

      Kero Katja; Hieta Niina; Kallonen Teemu; Ahtikoski Anne; Laine Hanna K; Rautava Jaana; Munukka Eveliina
      Next-generation sequencing-based microbiological analysis is a complex way to profile vaginal microbiome samples since each step affects the results gained. Methodologies for sample collection lack golden standards. We ...

    • Surgical Residents´ Results Seem to be Non-Inferior Comparing to More Experienced Surgeons in Femoral Neck Fracture Osteosynthesis 

      Forsbacka Nora; Kolari Terhi; Talme Marjo; Bister Ville
      <p><strong>Purpose of the Study</strong> Femoral neck fracture osteosynthesis is usually performed by using dynamic hip screw (DHS) or multiple parallel cannulated screws (MCS). In orthopedic surgery training, certain hip ...

    • The Fermi-LAT Lightcurve Repository 

      Abdollahi S; Ajello M; Baldini L; Ballet J; Bastieri D; Gonzalez JB; Bellazzini R; Berretta A; Bissaldi E; Bonino R; Brill A; Bruel P; Burns E; Buson S; Cameron RA; Caputo R; Caraveo PA; Cibrario N; Ciprini S; Orestano PC; Crnogorcevic M; Cutini S; D'Ammando F; De Gaetano S; Digel SW; Di Lalla N; Di Venere L; Dominguez A; Ramazani VF; Fegan SJ; Ferrara EC; Fiori A; Fleischhack H; Franckowiak A; Fukazawa Y; Fusco P; Gammaldi V; Gargano F; Garrappa S; Gasbarra C; Gasparrini D; Giglietto N; Giordano F; Giroletti M; Green D; Grenier IA; Guiriec S; Gustafsson M; Hays E; Horan D; Hou X; Johannesson G; Kerr M; Kocevski D; Kuss M; Latronico L; Li J; Liodakis I; Longo F; Loparco F; Lorusso L; Lott B; Lovellette MN; Lubrano P; Maldera S; Manfreda A; Marti-Devesa G; Mazziotta MN; Mereu I; Meyer M; Michelson PF; Mizuno T; Monzani ME; Morselli A; Moskalenko IV; Negro M; Omodei N; Orlando E; Ormes JF; Paneque D; Panzarini G; Perkins JS; Persic M; Pesce-Rollins M; Pillera R; Porter TA; Principe G; Racusin JL; Raino S; Rando R; Rani B; Razzano M; Razzaque S; Reimer A; Reimer O; Sanchez-Conde M; Parkinson PMS; Scargle J; Scotton L; Serini D; Sgro C; Siskind EJ; Spandre G; Spinelli P; Suson DJ; Tajima H; Thompson DJ; Torres DF; Valverde J; Venters T; Wadiasingh Z; Wagner S; Wood K
      The Fermi Large Area Telescope (LAT) lightcurve repository (LCR) is a publicly available, continually updated library of gamma-ray lightcurves of variable Fermi-LAT sources generated over multiple timescales. The Fermi-LAT ...

    • The role of the LysR-type transcription factor PacR in regulating nitrogen metabolism in Anabaena sp. PCC7120 

      Werner, Elisa; Huokko, Tuomas; Santana-Sánchez, Anita; Picossi, Silvia; Nikkanen, Lauri; Herrero, Antonia; Allahverdiyeva, Yagut
      <p>In the filamentous cyanobacterium <i>Anabaena</i> sp. PCC 7120, heterocyst formation is triggered by changes in the C/N-ratio and relies on transcriptional reprogramming. The transcription factor PacR is considered a ...