Viimeksi syötetyt
Aineistot 14281-14300 / 46678
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Inhibition of Excessive Oxidative Protein Folding Is Protective in MPP+ Toxicity-Induced Parkinson's Disease Models
Aims: Protein misfolding occurs in neurodegenerative diseases, including Parkinson's disease (PD). In endoplasmic reticulum (ER), an overload of misfolded proteins, particularly alpha-synuclein (alpha Syn) in PD, may cause ... -
Requirements Meet Reality: Finnish Teachers’ Practices in Linguistically Diverse Classrooms
<p>The current Finnish core curriculum requires all teachers in basic education to be linguistically responsive. However, studies on the linguistically responsive practices used by teachers are scarce. The frequency with ... -
The "Goldilocks Day" for Children's Skeletal Health: Compositional Data Analysis of 24-Hour Activity Behaviors
Optimization of children's activity behaviors for skeletal health is a key public health priority, yet it is unknown how many hours of moderate to vigorous physical activity (MVPA), light physical activity (LPA), sedentary ... -
Relationship between screen time and sleep among Finnish preschool children: results from the DAGIS study
<div><h3>Study objectives</h3><p>To examine the associations between screen time, the time spent on different screen devices, and sleep in a sample of Finnish preschool children.</p></div><div><h3>Methods</h3><p>The ... -
Globaalimuutoksen vaikutus porotalouteen Pohjois-Fennoskandian tundra-alueilla
Turun yliopiston maantieteen ja geologian laitoksen julkaisuja<p>Pohjoismainen huippuyksikkö (NCoE) TUNDRA <i>(“How to preserve the tundra in a changing climate”)</i> oli NordForskin alaisen huippututkimusaloitteen (TRI) viisivuotinen tutkimushanke (2011–15). Tässä tutkimusraportissa ... -
From information seeking to information avoidance: Understanding the health information behavior during a global health crisis
<p>Individuals seek information for informed decision-making, and they consult a variety of information sources nowadays. However, studies show that information from multiple sources can lead to information overload, which ... -
Keratins Are Altered in Intestinal Disease-Related Stress Responses
<p>Keratin (K) intermediate filaments can be divided into type I/type II proteins, which form obligate heteropolymers. Epithelial cells express type I-type II keratin pairs, and K7, K8 (type II) and K18, K19 and K20 (type ... -
An additive Gaussian process regression model for interpretable non-parametric analysis of longitudinal data
<p>Biomedical research typically involves longitudinal study designs where samples from individuals are measured repeatedly over time and the goal is to identify risk factors (covariates) that are associated with an ... -
Quantitative myocardial perfusion response to adenosine and regadenoson in patients with suspected coronary artery disease
Background The aim of the present study was to compare the quantitative flow responses of regadenoson against adenosine using cardiac O-15-water PET imaging in patients with suspected or known coronary artery disease (CAD). ... -
Antizyme inhibitor 2 (AZIN2) associates with better prognosis of head and neck minor salivary gland adenoid cystic carcinoma
The key regulator of the polyamine biosynthetic pathway is ornithine decarboxylase (ODC). ODC is activated by antizyme inhibitor 1 (AZIN1) and 2 (AZIN2). AZIN1 and recently AZIN2 have been related to cancer; however, their ... -
Sex‐specific role of alexithymia in associations between parental bonding and mental health: A moderated mediation model
<p><strong>Objective: </strong>This study aimed to explore the role of alexithymia and potential sex differences in the associations between perceived parental bonding and mental health.</p><p><strong>Methods: </strong>The ... -
Active site closure stabilizes the backtracked state of RNA polymerase
<p>All cellular RNA polymerases (RNAP) occasionally backtrack along the template DNA as part of transcriptional proofreading and regulation. Here, we studied the mechanism of RNAP backtracking by one nucleotide using two ... -
SNPs in lncRNA Regions and Breast Cancer Risk
<div><p>Long non-coding RNAs (lncRNAs) play crucial roles in human physiology, and have been found to be associated with various cancers. Transcribed ultraconserved regions (T-UCRs) are a subgroup of lncRNAs conserved ... -
Encountering sexual and gender minority youth in healthcare: an integrative review
<div>Aim<p>To describe the encounters with sexual and gender minority (SGM) youth in healthcare based on the existing research.</p></div><div>Background<p>The development of sexual orientation and gender identity can create ... -
Religion, Ethnicity, and Race in Finnish Legal Cases on Insults against Religion
This article examines religious insults and related legal practice in Finland during the 21st century. It investigates how the Office of the Prosecutor General, the courts, and defendants construct the category of religion ... -
Asian elephants exhibit post-reproductive lifespans
Background The existence of extended post-reproductive lifespan is an evolutionary puzzle, and its taxonomic prevalence is debated. One way of measuring post-reproductive life is with post-reproductive representation, the ... -
A SCUBA-2 850 mu m survey of heavily reddened quasars at z similar to 2
We present new 850 p.m SCUBA-2 observations for a sample of 19 heavily reddened Type-1 quasars at redshills z 2 with dust extinctions of Av 2-6 mag. Three of the 19 quasars arc detected at >3a significance corresponding ...
