Viimeksi syötetyt
Aineistot 21961-21980 / 46619
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QuantISH: RNA in situ hybridization image analysis framework for quantifying cell type-specific target RNA expression and variability
RNA in situ hybridization (RNA-ISH) is a powerful spatial transcriptomics technology to characterize target RNA abundance and localization in individual cells. This allows analysis of tumor heterogeneity and expression ... -
Information Systems Management — Modular Approach
<p>Information systems management can be a challenging task, especially in a smaller organization. In smaller organizations the resources tend to be limited, and often there are is no IT staff or expertize in the organization. ... -
Skin microbiota diversity among genetically unrelated individuals of Indian origin
<p><br></p><p>Background<br></p><p>Human skin harbors complex transient and resident microbial communities that show intra- & inter-individual variation due to various environmental and host-associated factors such as skin ... -
Inner-shell-ionization-induced femtosecond structural dynamics of water molecules imaged at an x-ray free-electron laser
<p>The ultrafast structural dynamics of water following inner-shell ionization is a crucial issue in high-energy radiation chemistry. We have exposed isolated water molecules to a short x-ray pulse from a free-electron ... -
PHACTR1 genetic variability is not critical in small vessel ischemic disease patients and PcomA recruitment in C57BL/6J mice
<p>Recently, several genome-wide association studies identified <em>PHACTR1</em> as key locus for five diverse vascular disorders: coronary artery disease, migraine, fibromuscular dysplasia, cervical artery dissection and ... -
Online dating applications and risk of youth victimization: A lifestyle exposure perspective
<p>Based on lifestyle exposure theory (LET), this study examined online dating application (ODA) use and victimization experiences among adolescents using large cross-national samples of Finnish, American, Spanish, and ... -
Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes - Type 1 Diabetes Prediction and Prevention Study (DIPP)
Type 1 diabetes (T1D) is one of the most prevalent autoimmune diseases among children in Western countries. Earlier metabolomics studies suggest that T1D is preceded by dysregulation of lipid metabolism. Here we used a ... -
Hypoxia reveals a new function of Foxn1 in the keratinocyte antioxidant defense system
<p> Skin exposed to environmental threats, including injuries and oxidative stress, develops an efficient but not fully recognized system of repair and antioxidant protection. Here, using mass spectrometry analysis (LC–MS/MS), ... -
Methyljasmonate Elicitation Increases Terpenoid Indole Alkaloid Accumulation in Rhazya stricta Hairy Root Cultures
Methyl jasmonate is capable of initiating or improving the biosynthesis of secondary metabolites in plants and therefore has opened up a concept for the biosynthesis of valuable constituents. In this study, the effect of ... -
Buchbesprechung
<p>A Treatise of Legal Philosophy and General Jurisprudence. Book Series. With Enrico Pattaro (Editor-in-Chief); Gerald J. Postema/Peter G. Stein (Associate Editors); Antonino Rotolo (Assistant Editor) and Individual Authors ... -
Development of an Online Learning Platform for University Pedagogical Studies-Case Study
<p>Due to a high demand of university pedagogical staff development courses in our university, we were faced with the problem of not being able to offer university pedagogy courses for everyone who wanted to study them. ... -
ePCR: an R-package for survival and time-to-event prediction in advanced prostate cancer, applied to real-world patient cohorts
<h4>Motivation: </h4><p>Prognostic models are widely used in clinical decision-making, such as risk stratification and tailoring treatment strategies, with the aim to improve patient outcomes while reducing overall healthcare ... -
A Systematic Pipeline to Enhance the Fecal Metabolome Coverage by LC-HRMS
<p>The comprehended knowledge of the metabolic profile of the fecal matter has been recognized as an important point for understanding metabolic changes in the human systemic metabolism and it can provide precious information ... -
Scenario Adaptation for Creative and Transformative Innovation
<p>In these times of crisis, it has been proposed that we need to consider wider more radical and even transformative innovation potentials to meet future challenges. Considering this, also futures scenarios should ... -
No Effects of Stimulating the Left Ventrolateral Prefrontal Cortex with tDCS on Verbal Working Memory Updating
The effects of transcranial direct current stimulation (tDCS) on dorsolateral prefrontal cortex functions, such as working memory (WM), have been examined in a number of studies. However, much less is known about the ... -
Diagnostic value of micrographia in Parkinson's disease: a study with [I-123]FP-CIT SPECT
<p>Micrographia is a common symptom of Parkinson's disease (PD), and it may precede other motor symptoms. Despite the high prevalence of micrographia in PD, its neurobiological mechanisms are not known. Given that levodopa ...
