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Aineistot 22521-22540 / 45877

    • Helper T Cell (CD4(+)) Targeted Tacrolimus Delivery Mediates Precise Suppression of Allogeneic Humoral Immunity 

      Liu Shuaihui; Huang Hongfeng; Chen Jianghua; Wang Rending; Guo Luying; Rosenholm Jessica M; Yan Pengpeng; Liu Chang; Zhang Hongbo; Wang Meifang; Shen Jia
      Antibody-mediated rejection (ABMR) is a major cause of dysfunction and loss of transplanted kidney. The current treatments for ABMR involve nonspecific inhibition and clearance of T/B cells or plasma cells. However, the ...
    • LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases 

      Jaddoe Vincent W. V.; d’Amico Enrico; Rundblad Amanda; Kajantie Eero; Vääräsmäki Marja; Atella Vincenzo; de Rooij Susanne R.; Matthews Jason; Heude Barbara; Zarei Iman; Piano Mortari Andrea; Hanhineva Kati; Kavousi Maryam; Sebert Sylvain; on behalf of the LongITools Project Group; Simonetti Valentina; Belotti Federico; Kerckhoffs Jules; Savolainen Otto; Ribbenstedt Anton; Jacquemin Bénédicte; de Toro Eadie Nina; Haakma Sido; Holven Kirsten B.; Lakka Timo; Keikkala Elina; Klåvus Anton; Näätänen Mari; Ronkainen Justiina; Chadeau-Hyam Marc; Kolehmainen Marjukka; Hoek Gerard; Halonen Miia; Parusso Stefano; Felix Janine F.; Kopinska Joanna A.; Lekadir Karim; Zins Marie; van Enckevort Esther; Voortman Trudy; Hyde Eleanor; Nedelec Rozenn; Heiskala Anni; Webster Claire; Ngoc Dang Vien; Gaillard Romy; Motoc Irina; Cascarano Anna; Tzala Evangelia; Kaakinen Marika A.; Heil Katharina F.; Marazzi Francesca; Evans Jayne; Ulven Stine M.; Wright Thomas; Roseboom Tessa; Vermeulen Roel; Castleton Christopher; Prokopenko Inga; Lepeule Johanna; Landberg Rikard; Bulgheroni Maria; Ulrich Anna; Goncalves Soares Ana; Charles Marie-Aline; Järvelin Marjo-Riitta; Swertz Morris; Timpson Nicholas; Elhakeem Ahmed; Brunius Carl; Juola Teija; Balkhiyarova Zhanna; Conti Gabriella; Atehortua Angelica
      <p>The current epidemics of cardiovascular and metabolic noncommunicable diseases have emerged alongside dramatic modifications in lifestyle and living environments. These correspond to changes in our “modern” postwar ...
    • Evaluating the content validity of two versions of an instrument used in measuring pediatric pain knowledge and attitudes in the Ghanaian context 

      Bam V; Axelin A; Korhonen J; Stolt M; Kusi Amponsah A
      <p>In this article, we compared the content validity of two instruments used in measuring pediatric pain knowledge and attitudes. This was considered necessary due to the universal differences in culture, semantics and ...
    • An update on semen quality among young Finnish men and comparison with Danish data 

      Toppari J; Rodprasert W; Skakkebaek NE; Jørgensen N; Perheentupa A; Sadov S; Virtanen HE
      Finnish men used to have higher semen quality than Danish men. However, recent studies showed that semen quality in Finland has declined, but it has been relatively stable in Denmark.\nThis study aimed to compare new data ...
    • Sex Difference in the Case Fatality of Older Myocardial Infarction Patients 

      Kytö Ville; Rautava Päivi; Nuotio Maria
      <p><strong>Background: </strong>The female sex is associated with poorer outcomes after myocardial infarction (MI), although current evidence in older patients is limited and mixed. We sought to evaluate sex-based differences ...
    • Comparison of mid-age-onset and late-onset Huntington's disease in Finnish patients 

      Jussi O. T. Sipilä; Tommi Kauko; Kari Majamaa; Markku Päivärinta
      The phenotype of juvenile Huntington's disease (HD) differs clearly from that of adult-onset HD, but information about differences between mid-age-onset HD and late-onset HD (LOHD) is scarce. A national cohort of 206 ...
    • Covalently Palladated Oligonucleotides Through Oxidative Addition of Pd-0 

      Räisälä H.; Lönnberg T.
      An 11-mer oligonucleotide incorporating a central (2-iodobenzoylamino)methyl residue has been synthesized and palladated by oxidative addition of Pd-2(dba)(3). UV melting profiles of the duplexes formed by the palladated ...
    • Thrombotic microangiopathy associated with bortezomib treatment in a patient with relapsed multiple myeloma 

      Urpu Salmenniemi; Kari Remes
      Thrombotic thrombocytopenic purpura (TTP) and hemolytic-uremic syndrome (HUS) describe microvascular occlusive disorders characterized by thrombocytopenia due to increased platelet aggregation and fragmentation hemolysis. ...
    • Investigation of the correlation patterns and the Compton dominance variability of Mrk 421 in 2017 

      Lopez-Coto R; Kopatskaya EN; Lien AY; Saturni FG; Leone F; Chanishvili RG; Kajiwara Y; Hutten M; Zaric D; De Angelis A; Iotov R; Ubach S; Kurtanidze OM; Kerszberg D; Dazzi F; Tutone A; Priyadarshi C; Bigongiari C; Mendez CD; Colak SM; Pandey A; Hahn A; de Almeida UB; Merkulova OA; Menchiari S; Spencer M; Eisenberger L; Fukami S; Martinez M; Antonelli LA; Neustroev V; Loporchio S; Contreras JL; Miceli D; Jorstad SG; Buss J; Schleicher B; Righini S; Chilingarian A; Baquero A; Gasparyan S; Colombo E; Delgado J; Fraga BMD; Sigua LA; Di Pierro F; Artero M; Bernardos M; Engels AA; Troitskiy IS; Busetto G; Fonseca MV; Prester DD; Schweizer T; Fruck C; Lamastra A; Lin HC; Acosta-Pulido JA; Hoang J; Miener T; Acciari VA; Ramakrishnan V; Leto C; Otero-Santos J; Tornikoski M; Sakurai S; Makariev M; Larionova LV; DaVela P; Cerruti M; Ceribella G; Temnikov P; Green D; Casadio C; Mannheim K; Damljanovic G; Teshima M; Bretz T; Scherbantin A; Paoletti R; Persic M; Neise D; Manganaro M; Hagen-Thorn VA; Kopp M; Hildebrand D; Baack D; Verrecchia F; Paneque D; Reinhart D; Espineira ED; Saha L; Larionov VM; Weaver ZR; Chigladze RA; Nilsson K; Cortina J; Maneva G; Ventura S; Moreno V; Chen WP; Zaharieva E; Moretti E; Moralejo A; Marchini A; Marchili N; Nishijima K; Lindfors E; Donini A; Ferrara G; Agudo I; Ibryamov S; Verguilov V; Tavecchio F; Lahteenmaki A; Green JG; Palatiello M; Bachev R; Garczarczyk M; Mender S; Penil P; Kobayashi Y; Cikota S; Hadasch D; Vanzo G; Chai Y; Samal M; Herrera J; Villata M; Inoue S; Molina E; Sobczynska D; Ishio K; Semkov E; Prandini E; Nikolashvili MG; Perennes C; Jimenez I; Nikiforova AA; Morcuende D; Walter R; Delfino M; Nozaki S; Valcheva A; Hrupec D; Saito T; Strom D; De Lotto B; Gupta AC; Acosta MV; Font L; Biederbeck N; Kimeridze GN; Oka T; Maraschi L; Covino S; Rugliancich A; Wunderlich C; Schneider L; Bernardini E; Vince O; Righi C; Ovcharov E; Vasilyev AA; Lopez-Moya M; Mirzoyan R; Bonnoli G; Troitskaya YV; van Scherpenberg J; Gliwny P; Puljak I; Barrio JA; Biland A; Nigro C; Balokovic M; Gaug M; Sahakyan N; Kunkel L; Karjalainen M; Suda Y; Majumdar P; DiVenere L; Bozhilov V; Heckmann L; Vitale V; Lopez-Oramas A; Giordano F; Mallamaci M; Ivanidze RZ; D'Amico G; Iwamura Y; Sadun AC; Bosnjak Z; Paravac A; Satalecka K; Perri M; Kushida J; Maggio C; Noethe M; Strigachev A; Will M; Ansoldi S; Truzzi S; Noda K; Inada T; Raiteri CM; Paiano S; Jarvela E; Kurtanidze SO; Jouvin L; Joner MD; Longo F; Carnerero MI; Lorey C; Besenrieder J; Savchenko SS; Rizzi N; Moody JW; Vera RJC; Snidaric I; Elsaesser D; Carosi R; Ribo M; Rhode W; Paredes JM; D'Elia V; D'Ammando F; Dorner D; Horan D; Asano K; Berti A; Marscher AP; Borman GA; Kubo H; Lombardi S; Moroni PGP; Minev M; Carosati D; Giglietto N; Rico J; Sliusar V; Strzys M; Blanch O; Doro M; Gonzalez JB; Takahashi M; Ohtani Y; Vigorito CF; Tosti L; Stamerra A; Ramazani VF; Madejski GM; Grishina TS; Feige M; Bednarek W; Sitarek J; Depaoli D; Fattorini A; Larionova EG; Lelas D; Balbo M; Vovk I; Jormanainen J; Fuentes A; Bellizzi L; Spolon A; Bhattacharyya W; Kania J; Morozova DA; Miranda JM; Giroletti M; Schmidt K; Mariotti M; Mazin D; Lopez RJG
      <p><b>Aims</b>. We present a detailed characterisation and theoretical interpretation of the broadband emission of the paradigmatic TeV blazar Mrk 421, with a special focus on the multi-band flux correlations.<br></p><p> ...
    • Cultural sensemaking of corporate social responsibility: A dyadic view of Russian–Finnish business relationships 

      Kulkov Ignat; Hannibal Martin; Dziubaniuk Olga; Uzhegova Maria; Barner-Rasmussen Wilhelm; Torkkeli Lasse; Ivanova-Gongne Maria
      <p> International Management (IM) needs a better understanding of how managers of small and medium-sized enterprises (SMEs) make sense of cultural differences in international business relationships, especially regarding ...
    • Gender and Innovation: State of the Art and a Research Agenda 

      Hytti U; Ljunggren E; Alsos GA
      <p><strong>Purpose - </strong>The purpose of the article is to present a framework for research on gender and innovation. The framework is developed based on a review of current literature in the area; it is applied to ...
    • Edge-Assisted Control for Healthcare Internet of Things: A Case Study on PPG-Based Early Warning Score 

      Arman Anzanpour; Iman Azimi; Nikil Dutt; Amir M. Rahmani; Pasi Liljeberg; Delaram Amiri; Marco Levorato
    • Childhood Socioeconomic Disadvantage and Risk of Fatty Liver in Adulthood: The Cardiovascular Risk in Young Finns Study 

      Tomi Laitinen; Jussi Vahtera; Terho Lehtimäki; Eero Jokinen; Joel Nuotio; Jorma S.A. Viikari; Jaana Pentti; Päivi Tossavainen; Tomi T. Laitinen; Nina Hutri‐Kähönen; Mika Kivimäki; Olli T. Raitakari; Katja Pahkala; Costan G. Magnussen; Markus Juonala
      Fatty liver is a preventable cause of liver failure, but early risk factors for adulthood fatty liver are poorly understood. We examined the association of childhood socioeconomic disadvantage with adulthood fatty liver ...
    • Recent breakthroughs in metastatic uveal melanoma: a cause for optimism? 

      Figueiredo CR; Coulson JM; Coupland SE; Sacco JJ; Kalirai H; Kenyani J
    • Transdisciplinary research in natural resources management: Towards an integrative and transformative use of co-concepts 

      Hakkarainen Viola; Mäkinen-Rostedt Katri; D'Amato Dalia; Jämsä Johanna; Soini Katriina; Horcea-Milcu Andra
      Transdisciplinary research often utilizes collaborative ways of knowledge production to enable deliberate transformations towards sustainability. Multiple concepts with varying definitions are applied, leading to confusion ...
    • Hooked on a feeling? An interpretive study of organizational identity (dis)continuity during strategic change programmes† 

      Harikkala-Laihinen Riikka
      <p>This paper explores how organizational members perceive identity (dis)continuity when they are caught in the crossfire during strategic change programmes. Illustrative data stems from a Finnish company that underwent a ...
    • Interspecific transfer of parasites following a range-shift in Ficedula flycatchers 

      Moreno J.; Slater F.; Szöllősi E.; Munclinger P.; Cichoń M.; Laaksonen T.; Krist M.; Qvarnström A.; Visser M.; Kulma K.; Jones W.; Bensch S.; Kerimov A.
      <p>Human‐induced climate change is expected to cause major biotic changes in species distributions and thereby including escalation of novel host‐parasite associations. Closely related host species that come into secondary ...
    • Impact of Age and Comorbidity on Multimodal Management and Survival from Colorectal Cancer: A Population-Based Study 

      Kuopio Teijo; Kellokumpu Ilmo; Wirta Erkki-Ville; Seppälä Toni T.; Kellokumpu Henrik; Mecklin Jukka-Pekka; Väyrynen Ville; Sihvo Eero; Kairaluoma Matti
      This retrospective population-based study examined the impact of age and comorbidity burden on multimodal management and survival from colorectal cancer (CRC). From 2000 to 2015, 1479 consecutive patients, who underwent ...