Viimeksi syötetyt
Aineistot 22521-22540 / 45877
-
Helper T Cell (CD4(+)) Targeted Tacrolimus Delivery Mediates Precise Suppression of Allogeneic Humoral Immunity
Antibody-mediated rejection (ABMR) is a major cause of dysfunction and loss of transplanted kidney. The current treatments for ABMR involve nonspecific inhibition and clearance of T/B cells or plasma cells. However, the ... -
LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases
<p>The current epidemics of cardiovascular and metabolic noncommunicable diseases have emerged alongside dramatic modifications in lifestyle and living environments. These correspond to changes in our “modern” postwar ... -
Evaluating the content validity of two versions of an instrument used in measuring pediatric pain knowledge and attitudes in the Ghanaian context
<p>In this article, we compared the content validity of two instruments used in measuring pediatric pain knowledge and attitudes. This was considered necessary due to the universal differences in culture, semantics and ... -
An update on semen quality among young Finnish men and comparison with Danish data
Finnish men used to have higher semen quality than Danish men. However, recent studies showed that semen quality in Finland has declined, but it has been relatively stable in Denmark.\nThis study aimed to compare new data ... -
Sex Difference in the Case Fatality of Older Myocardial Infarction Patients
<p><strong>Background: </strong>The female sex is associated with poorer outcomes after myocardial infarction (MI), although current evidence in older patients is limited and mixed. We sought to evaluate sex-based differences ... -
Comparison of mid-age-onset and late-onset Huntington's disease in Finnish patients
The phenotype of juvenile Huntington's disease (HD) differs clearly from that of adult-onset HD, but information about differences between mid-age-onset HD and late-onset HD (LOHD) is scarce. A national cohort of 206 ... -
Covalently Palladated Oligonucleotides Through Oxidative Addition of Pd-0
An 11-mer oligonucleotide incorporating a central (2-iodobenzoylamino)methyl residue has been synthesized and palladated by oxidative addition of Pd-2(dba)(3). UV melting profiles of the duplexes formed by the palladated ... -
Thrombotic microangiopathy associated with bortezomib treatment in a patient with relapsed multiple myeloma
Thrombotic thrombocytopenic purpura (TTP) and hemolytic-uremic syndrome (HUS) describe microvascular occlusive disorders characterized by thrombocytopenia due to increased platelet aggregation and fragmentation hemolysis. ... -
Investigation of the correlation patterns and the Compton dominance variability of Mrk 421 in 2017
<p><b>Aims</b>. We present a detailed characterisation and theoretical interpretation of the broadband emission of the paradigmatic TeV blazar Mrk 421, with a special focus on the multi-band flux correlations.<br></p><p> ... -
Cultural sensemaking of corporate social responsibility: A dyadic view of Russian–Finnish business relationships
<p> International Management (IM) needs a better understanding of how managers of small and medium-sized enterprises (SMEs) make sense of cultural differences in international business relationships, especially regarding ... -
Gender and Innovation: State of the Art and a Research Agenda
<p><strong>Purpose - </strong>The purpose of the article is to present a framework for research on gender and innovation. The framework is developed based on a review of current literature in the area; it is applied to ... -
Childhood Socioeconomic Disadvantage and Risk of Fatty Liver in Adulthood: The Cardiovascular Risk in Young Finns Study
Fatty liver is a preventable cause of liver failure, but early risk factors for adulthood fatty liver are poorly understood. We examined the association of childhood socioeconomic disadvantage with adulthood fatty liver ... -
Transdisciplinary research in natural resources management: Towards an integrative and transformative use of co-concepts
Transdisciplinary research often utilizes collaborative ways of knowledge production to enable deliberate transformations towards sustainability. Multiple concepts with varying definitions are applied, leading to confusion ... -
Hooked on a feeling? An interpretive study of organizational identity (dis)continuity during strategic change programmes†
<p>This paper explores how organizational members perceive identity (dis)continuity when they are caught in the crossfire during strategic change programmes. Illustrative data stems from a Finnish company that underwent a ... -
Interspecific transfer of parasites following a range-shift in Ficedula flycatchers
<p>Human‐induced climate change is expected to cause major biotic changes in species distributions and thereby including escalation of novel host‐parasite associations. Closely related host species that come into secondary ... -
Impact of Age and Comorbidity on Multimodal Management and Survival from Colorectal Cancer: A Population-Based Study
This retrospective population-based study examined the impact of age and comorbidity burden on multimodal management and survival from colorectal cancer (CRC). From 2000 to 2015, 1479 consecutive patients, who underwent ...