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Aineistot 22581-22600 / 54761
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Associations between deduced first islet specific autoantibody with sex, age at diagnosis and genetic risk factors in young children with type 1 diabetes
<p>Objectives We aimed to further characterize demography and genetic associations of type 1 diabetes "endotypes" defined by the first appearing islet specific autoantibodies. Research Design and Methods We analyzed 3277 ... -
Early administration of tocilizumab in hospitalized COVID-19 patients with elevated inflammatory markers; COVIDSTORM—a prospective, randomized, single-centre, open-label study
<p>Objectives</p><p>Severe COVID-19 is associated with an imbalanced immune response. We hypothesized that patients with enhanced inflammation, as demonstrated by increased levels of certain inflammatory biomarkers, would ... -
Substrate Selectivity of Coumarin Derivatives by Human CYP1 Enzymes: In Vitro Enzyme Kinetics and In Silico Modeling
Of the three enzymes in the human cytochrome P450 family 1, CYP1A2 is an important enzyme mediating metabolism of xenobiotics including drugs in the liver, while CYP1A1 and CYP1B1 are expressed in extrahepatic tissues. ... -
The significance of music in early childhood education and care of toddlers in Finland: an extensive observational study
<p>The present study investigated the role of music education in early childhood education and care (ECEC) in relation to the daily activities of children ages one to three, i.e. <i>toddlers</i> (<i>N</i> = 918) in Finnish ... -
Decay of a massive particle in a stiff-matter-dominated universe
In the presence of a gravitational field, decay rates may significantly differ from the flat space equivalent. By studying mutually interacting quantum fields, the decay rates can be calculated on a given spacetime. This ... -
Uncovering the complex genetics of human character
<p>Human personality is 30–60% heritable according to twin and adoption studies. Hundreds of genetic variants are expected to influence its complex development, but few have been identified. We used a machine learning ... -
Sleeping behaviors of adolescents with depressive disorders: adolescent self-description of sleeping reported through a web-based support system
Background: Depression is the leading health disorder in adolescence and often manifests itself as sleeping problems. A number of quantitative analyses have assessed the quality of adolescents' sleeping, but there is still ... -
Body size and tree species composition determine variation in prey consumption in a forest-inhabiting generalist predator
Trophic interactions may strongly depend on body size and environmental variation, but this prediction has been seldom tested in nature. Many spiders are generalist predators that use webs to intercept flying prey. The ... -
Prevention of gestational diabetes through lifestyle intervention: study design and methods of a Finnish randomized controlled multicenter trial (RADIEL)
<h4> Background</h4> <p style="line-height:160%"> Maternal overweight, obesity and consequently the incidence of gestational diabetes are increasing rapidly worldwide. The objective of the study was to assess the ... -
Multisystem Trajectories Over the Adult Life Course and Relations to Cardiovascular Disease and Death
<div>Background</div><p>Comprehensive conjoint characterization of long-term trajectories representing several biological systems is lacking.</p><div>Methods</div><p>We measured serially indicators representing 14 distinct ... -
Phosphonate production by marine microbes: Exploring new sources and potential function
<p>Phosphonates are organophosphorus metabolites with a characteristic C-P bond. They are ubiquitous in the marine environment, their degradation broadly supports ecosystem productivity, and they are key components of the ... -
Determinants of carrier selection: updating the survey methodology into the 21st century
This paper summarizes the key developments of carrier selection literature, especially from the view of survey research. Based on the literature review suggestions on how to make the analysis of carrier selection more ... -
The black hole – host galaxy relation for very low mass quasars – Very low mass BH – host galaxy relation
<p> Recently, the relation between the masses of the black hole (<em>M</em><sub>BH</sub>) and the host galaxy (<em>M</em><sub>host</sub>) in quasars has been probed down to the parameter space of <em>M</em><sub>BH</sub ... -
On t-revealing codes in binary Hamming spaces
In this paper, we introduce t-revealing codes in the binary Hamming space F-n. Let C subset of F-n be a code and denote by I-t (C; x) the set of elements of C which are within (Hamming) distance t from a word x is an element ... -
Moderate Conventionalism and Cultural Appropriation
<h3>Abstract</h3><p>Cultural appropriation, also called cultural borrowing, has been the topic of much discussion in recent years. Roughly speaking, cultural appropriation happens when someone outside of a cultural or ... -
Highlight selection of radiochemistry and radiopharmacy developments by editorial board
<p>Background</p><p>The Editorial Board of EJNMMI Radiopharmacy and Chemistry releases a biyearly highlight commentary to update the readership on trends in the field of radiopharmaceutical development.</p><p>Results</p><p>This ... -
Traduction et vulgarisation; de la métaphorisation à la dissémination
<p>Translation and popularization have seldom been studied together. The article is divided into three sections. The first one recalls how popularization has been conceptualized, partly by referring to the “translation” ...
