Viimeksi syötetyt
Aineistot 25641-25660 / 54830
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Relationship between screen time and sleep among Finnish preschool children: results from the DAGIS study
<div><h3>Study objectives</h3><p>To examine the associations between screen time, the time spent on different screen devices, and sleep in a sample of Finnish preschool children.</p></div><div><h3>Methods</h3><p>The ... -
Active site closure stabilizes the backtracked state of RNA polymerase
<p>All cellular RNA polymerases (RNAP) occasionally backtrack along the template DNA as part of transcriptional proofreading and regulation. Here, we studied the mechanism of RNAP backtracking by one nucleotide using two ... -
Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy
Ketamine is a phencyclidine derivative, which functions primarily as an antagonist of the N-methyl-d-aspartate receptor. It has no affinity for gamma-aminobutyric acid receptors in the central nervous system. Ketamine shows ... -
Micro-foundations of Organizational Ambidexterity in the Context of Cross-Border Mergers and Acquisitions
Micro-foundational approaches can enable firms to develop organizational ambidexterity, which is critical to long-term prosperity. However, to date, few studies have examined how mergers and acquisitions (M&A)—processes ... -
Auditory attentional set-shifting and inhibition in children who stutter
<p>Purpose: The purpose of this study was to investigate whether previously reported parental questionnaire-based differences in attentional shifting and inhibitory control (AS and IC; Eggers, De Nil, & Van den Bergh, 2010) ... -
Urine microRNA Profiling Displays miR-125a Dysregulation in Children with Fragile X Syndrome
A triplet repeat expansion leading to transcriptional silencing of the FMR1 gene results in fragile X syndrome (FXS), which is a common cause of inherited intellectual disability and autism. Phenotypic variation requires ... -
Digoxin use and outcomes after myocardial infarction in patients with atrial fibrillation
Digoxin is used for rate control in atrial fibrillation (AF), but evidence for its efficacy and safety after myocardial infarction (MI) is scarce and mixed. We studied post-MI digoxin use effects on AF patient outcomes in ... -
Economic Mobility and Fiscal Federalism: Taxation and European Responses in a Changing Constitutional Context
<p>In this article we explore the claim that the four freedoms of the EU lead to the inevitable erosion of the capacity of Member States to collect tax, undermining national systems of welfare and solidarity. We argue that ... -
PIM kinases inhibit AMPK activation and promote tumorigenicity by phosphorylating LKB1
<p>Background<br></p><p>The oncogenic PIM kinases and the tumor-suppressive LKB1 kinase have both been implicated in the regulation of cell growth and metabolism, albeit in opposite directions. Here we investigated whether ... -
Associations of Different Types of Maternal Diabetes and Body Mass Index With Offspring Psychiatric Disorders
<p><strong>Question</strong> Are different types of maternal diabetes, by themselves or in combination with maternal obesity, associated with an increased risk of offspring psychiatric disorders? <strong>Findings</strong> ... -
Final Year Nursing Students' Knowledge and Attitudes regarding Children's Pain
Pain is one of the commonest reasons why children visit the hospital. Inadequately treated pain in children can negatively affect their physical, psychological, and social well-being; it also places financial burden on ... -
Continuous synthesis of menthol from citronellal and citral over Ni-beta-zeolite-sepiolite composite catalyst
<p>One-pot continuous synthesis of menthols both from citronellal and citral was investigated over 5 wt% Ni supported on H-Beta-38-sepiolite composite catalyst at 60–70 °C under 10–29 bar hydrogen pressure. A relatively ... -
Nimetön
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Futures Clinique - method for promoting futures learning and provoking radical futures
<span style="color: #333333; font-family: 'Helvetica Neue', Arial, Helvetica, sans-serif; font-size: 13px; line-height: 20.799999237060547px;">This paper introduces, illustrates and evaluates the concept of Futures Clinique, ... -
Infant Sex Moderates the Effects of Maternal Pre- and Postnatal Stress on Executive Functioning at 8 Months of Age
<p>Previous studies report that early life stress, including maternal pre- and postnatal stress, has adverse effects on cognitive development and that these associations might be sex-specific. However, no studies exist on ... -
Metformin versus insulin therapy for gestational diabetes: Effects on offspring anthropometrics and metabolism at the age of 9 years: A follow-up study of two open-label, randomized controlled trials
<p>Aims<br>To compare anthropometrics, and lipid and glucose metabolism in the 9-year-old offspring of mothers treated with metformin or insulin for gestational diabetes mellitus (GDM).</p><p>Materials and Methods<br>This ...
