Viimeksi syötetyt
Aineistot 3621-3640 / 54761
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Pohjoiskarjalainen aivoinfarktipotilas 2020-luvulla
<p>JOHDANTO. Iskeeminen aivohaveri on merkittävä kuolleisuuden ja toimintakyvyn vajauksen aiheuttaja sekä Suomessa että maailmanlaajuisesti.<br>POTILAAT JA MENETELMÄT. Analysoimme Pohjois-Karjalan keskussairaalassa vuosina ... -
The effect of time of measurement on the discriminant ability for mortality in trauma of a pre-hospital shock index multiplied by age and divided by the Glasgow Coma Score: a registry study
<p>Background <br></p><p>The shock index (SI) and its derivatives have been shown to predict mortality in severely injured patients, both in pre-hospital and in-hospital settings. However, the impact of the time of measurement ... -
Parents’ Experiences on a Family Literacy Program in Finland
<p>In this article, we investigate a family literacy program called Bedtime Story Shelf, which is an application of lending libraries. In Bedtime Story Shelf-program the families are loaning books from ECE centers and ... -
Numerical computation of Mityuk's function and radius for circular/radial slit domains
<p>We consider Mityuk’s function and radius which have been proposed in [15]as generalizations of the reduced modulus and conformal radius to the cases of multiply connected domains. We present a numerical method to compute ... -
A core outcome set for future male infertility research: development of an international consensus
<p><strong>Study question: </strong>Can a core outcome set be developed through a global consensus to standardize outcome selection, collection, comparison, and reporting in future male infertility trials?</p><p><strong>Summary ... -
Comparative Case Studies: Methodological Discussion
Palgrave Studies in Adult Education and Lifelong Learning<p>Comparative Case Studies: Methodological DiscussionCase Study Research has a long tradition and it has been used in different areas of social sciences to approach research questions that command context sensitiveness ... -
FreeSurfer 7 quality control: Key problem areas and importance of manual corrections
<p>We have studied the effects of manual quality control of brain Magnetic Resonance Imaging (MRI) images processed with Freesurfer. T1 images of first episode psychosis patients (N = 60) and healthy controls (N = 41) were ... -
A novel polypeptide encoded by the circular RNA ZKSCAN1 suppresses HCC via degradation of mTOR
<p><strong>Background</strong></p><p>hsa_circ_0001727 (circZKSCAN1) has been reported to be a tumor-associated circRNA by sponging microRNAs. Intriguingly, we found that circZKSCAN1 encoded a secretory peptide (circZKSaa) ... -
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Load-bearing capacity and fracture behavior of glass fiber-reinforced composite cranioplasty implants
Background: Glass fiber-reinforced composites (FRCs) have been adapted for routine clinical use in various dental restorations and are presently also used in cranial implants. The aim of this study was to measure the ... -
Bioinspired and Multifunctional Tribological Materials for Sliding, Erosive, Machining, and Energy-Absorbing Conditions : A Review
Friction, wear, and the consequent energy dissipation pose significant challenges in systems with moving components, spanning various domains, including nanoelectromechanical systems (NEMS/MEMS) and bio-MEMS (microrobots), ... -
Paediatric maxillofacial fractures have increased in incidence and their nature and aetiology have changed during three decades
The safety of children's living environment is affected by several factors. Safer living environments have been offered as one explanation to decreases in children's fractures. Earlier studies provide evidence of a decreasing ... -
Time, the final frontier
<p>Cancer's notorious heterogeneity poses significant challenges, as each tumor comprises a unique ecosystem. While single-cell and spatial transcriptomics advancements have transformed our understanding of spatial diversity ... -
Self-reported involvement in road traffic crashes in Kenya: A cross-sectional survey of a nationally representative sample
<p>Background</p><p>Road traffic crashes (RTCs) are a global public health burden whose resulting morbidity and mortality disproportionately impact low- and middle-income countries with stressed health systems. There is a ... -
A head-to-head comparison of the efficacy and safety of ixekizumab and adalimumab in biological-naive patients with active psoriatic arthritis: 24-week results of a randomised, open-label, blinded-assessor trial
<b>Objectives </b>To compare efficacy and safety of ixekizumab (IXE) to adalimumab (ADA) in biological disease-modifying antirheumatic drug-naive patients with both active psoriatic arthritis (PsA) and skin disease and ... -
ParAquaSeq, a Database of Ecologically Annotated rRNA Sequences Covering Zoosporic Parasites Infecting Aquatic Primary Producers in Natural and Industrial Systems
Amplicon sequencing tools such as metabarcoding are commonly used for thorough characterisation of microbial diversity in natural samples. They mostly rely on the amplification of conserved universal markers, mainly ribosomal ... -
Delivery of Protein Kinase A by CRISPRMAX and Its Effects on Breast Cancer Stem-Like Properties
Protein kinase A (PKA) activation has recently been reported to inhibit epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC) ability, which is considered to be responsible for chemoresistance and tumor ... -
Boosting Glioblastoma Therapy with Targeted Pyroptosis Induction
<p>Glioblastoma (GBM) is a highly aggressive cancer that currently lacks effective treatments. Pyroptosis has emerged as a promising therapeutic approach for cancer, but there is still a need for new pyroptosis boosters ... -
IgG4:ään liittyvän taudin monimuotoinen kliininen kirjo
<p><em>Immunoglobuliini G4:ään liittyvä tauti (IgG4-tauti) on systeeminen immuunivälitteinen fibroosiin johtava tulehduksellinen sairaus, jossa on erotettu neljä pääasiallista kliinistä fenotyyppiä: 1) haiman ja sappiteiden ...
