Viimeksi syötetyt

Aineistot 381-400 / 58047

    • Luteinizing hormone receptor knockout mouse: What has it taught us? 

      Huhtaniemi, Ilpo T.
      <p>Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the ...

    • Euclid preparation : LII. Forecast impact of super-sample covariance on 3×2pt analysis with Euclid 

      Sciotti D.; Gouyou Beauchamps S.; Cardone V. F.; Camera S.; Tutusaus I.; Lacasa F.; Barreira A.; Bonici M.; Gorce A.; Aubert M.; Baratta P.; Upham R. E.; Carbone C.; Casas S.; Ilić S.; Martinelli M.; Sakr Z.; Schneider A.; Maoli R.; Scaramella R.; Escoffier S.; Gillard W.; Aghanim N.; Amara A.; Andreon S.; Auricchio N.; Baccigalupi C.; Baldi M.; Bardelli S.; Bernardeau F.; Bonino D.; Branchini E.; Brescia M.; Brinchmann J.; Capobianco V.; Carretero J.; Castander F. J.; Castellano M.; Castignani G.; Cavuoti S.; Cimatti A.; Cledassou R.; Colodro-Conde C.; Congedo G.; Conselice C. J.; Conversi L.; Copin Y.; Corcione L.; Courbin F.; Courtois H. M.; Cropper M.; Da Silva A.; Degaudenzi H.; De Lucia G.; Dinis J.; Dubath F.; Dupac X.; Dusini S.; Farina M.; Farrens S.; Fosalba P.; Frailis M.; Franceschi E.; Fumana M.; Galeotta S.; Garilli B.; Gillis B.; Giocoli C.; Grazian A.; Grupp F.; Guzzo L.; Haugan S. V. H.; Holmes W.; Hook I.; Hormuth F.; Hornstrup A.; Hudelot P.; Jahnke K.; Joachimi B.; Keihänen E.; Kermiche S.; Kiessling A.; Kunz M.; Kurki-Suonio H.; Lilje P. B.; Lindholm V.; Lloro I.; Mainetti G.; Maino D.; Mansutti O.; Marggraf O.; Markovic K.; Martinet N.; Marulli F.; Massey R.; Maurogordato S.; Medinaceli E.; Mei S.; Mellier Y.; Meneghetti M.; Meylan G.; Moresco M.; Moscardini L.; Munari E.; Neissner C.; Niemi S.-M.; Padilla C.; Paltani S.; Pasian F.; Pedersen K.; Pettorino V.; Pires S.; Polenta G.; Poncet M.; Popa L. A.; Raison F.; Rebolo R.; Renzi A.; Rhodes J.; Riccio G.; Romelli E.; Roncarelli M.; Saglia R.; Sánchez A. G.; Sapone D.; Sartoris B.; Schirmer M.; Schneider P.; Secroun A.; Sefusatti E.; Seidel G.; Serrano S.; Sirignano C.; Sirri G.; Stanco L.; Starck J.-L.; Steinwagner J.; Tallada-Crespí P.; Taylor A. N.; Tereno I.; Toledo-Moreo R.; Torradeflot F.; Valentijn E. A.; Valenziano L.; Vassallo T.; Veropalumbo A.; Wang Y.; Weller J.; Zacchei A.; Zamorani G.; Zoubian J.; Zucca E.; Biviano A.; Boucaud A.; Bozzo E.; Di Ferdinando D.; Farinelli R.; Graciá-Carpio J.; Mauri N.; Scottez V.; Tenti M.; Akrami Y.; Allevato V.; Ballardini M.; Blanchard A.; Borgani S.; Borlaff A. S.; Burigana C.; Cabanac R.; Cappi A.; Carvalho C. S.; Castro T.; Cañas-Herrera G.; Chambers K. C.; Cooray A. R.; Coupon J.; Davini S.; Desprez G.; Díaz-Sánchez A.; Di Domizio S.; Escartin Vigo J. A.; Ferrero I.; Finelli F.; Gabarra L.; Ganga K.; Garcia-Bellido J.; Gaztanaga E.; Giacomini F.; Gozaliasl G.; Hildebrandt H.; Jacobson J.; Kajava J. J. E.; Kansal V.; Kirkpatrick C. C.; Legrand L.; Loureiro A.; Macias-Perez J.; Magliocchetti M.; Martins C. J. A. P.; Matthew S.; Maurin L.; Metcalf R. B.; Migliaccio M.; Monaco P.; Morgante G.; Nadathur S.; Nucita A. A.; Patrizii L.; Pöntinen M.; Popa V.; Porciani C.; Potter D.; Pourtsidou A.; Sereno M.; Simon P.; Spurio Mancini A.; Stadel J.; Teyssier R.; Toft S.; Tucci M.; Valieri C.; Valiviita J.; Viel M.
      <p><em></em><br></p><p><em>Context</em>. Deviations from Gaussianity in the distribution of the fields probed by large-scale structure surveys generate additional terms in the data covariance matrix, increasing the ...

    • The role of statistical learning in the L2 acquisition and use of nonadjacent predicate-argument constructions 

      Guo; Jiaqi Feng; Pérez-Paredes; Pascual
      <p>While statistical learning of adjacent constructions is well-documented in SLA, our knowledge of this cognitive mechanism concerning nonadjacent constructions remains limited. To address this, we investigated the ...

    • Shell-dependent photofragmentation dynamics of a heavy-atom-containing bifunctional nitroimidazole radiosensitizer 

      Pihlava Lassi; Svensson Pamela H.W.; Kukk Edwin; Kooser Kuno; De Santis Emiliano; Tõnisoo Arvo; Käämbre Tanel; André Tomas; Akiyama Tomoko; Hessenthaler Lisa; Giehr Flavia; Björneholm Olle; Caleman Carl; Berholts Marta
      <p>Radiation therapy uses ionizing radiation to break chemical bonds in cancer cells, thereby causing DNA damage and leading to cell death. The therapeutic effectiveness can be further increased by making the tumor cells ...

    • Platelet inhibition strategies in rescue stenting after failed thrombectomy: a large retrospective multicenter registry 

      Anastasiou Aikaterini; Brehm Alex; Kaesmacher Johannes; Mujanovic Adnan; de Dios Lascuevas Marta; Carmona Fuentes Tomás; López-Frías Alfonso; Hidalgo Valverde Blanca; Berlis Ansgar; Maurer Christoph J.; Nguyen Thanh N.; Abdalkader Mohamad; Klein Piers; Thevoz Guillaume; Michel Patrik; Bartolini Bruno; Kaschner Marius; Weiss Daniel; Alexandre Andrea M.; Pedicelli Alessandro; Machi Paolo; Bernava Gianmarco; Kuwahara Shuntaro; Uchida Kazutaka; Wenderoth Jason; Joshi Anirudh; Karwacki Grzegorz; Bolognese Manuel; Tessitore Agostino; Vinci Sergio Lucio; Cervo Amedeo; Rollo Claudia; Hui Ferdinand; Mozumder Aaisha Siddiqua; Romano Daniele Giuseppe; Frauenfelder Giulia; Goyal Nitin; Batra Vivek; Inoa Violiza; Cognard Christophe; Hoferica Matúš; Rautio Riitta; Kaiser Daniel P. O.; Gerber Johannes C.; Clarke Julian; Levitt Michael R.; Wolf Marcel N.; Othman Ahmed E.; Scarcia Luca; Kalsoum Erwah; Melancia Diana; Sousa Diana Aguiar de; Ganimede Maria Porzia; Semeraro Vittorio; Giordano Flavio; Muto Massimo; Katsanos Aristeidis; Bonala Umesh; Tuladhar Anil M.; Jenniskens Sjoerd F. M.; Hellstern Victoria; Kleffner Ilka; Remida Paolo; Diamanti Susanna; Renieri Leonardo; Ballabio Elena; Valvassori Luca; Rommers Nikki; Katan Mira; Schulze-Zachau Victor; Psychogios Marios-Nikos
      <div><p><strong>Background: </strong> Rescue stenting (RS) is a bailout strategy for failed thrombectomy. Optimal platelet inhibition strategy after RS remains unclear.</p><p><strong>Objectives: </strong> We aimed to ...

    • Persistent T cell-mediated immune responses against Omicron variants after the third COVID-19 mRNA vaccine dose 

      Belik Milja; Liedes Oona; Vara Saimi; Haveri Anu; Pöysti Sakari; Kolehmainen Pekka; Maljanen Sari; Huttunen Moona; Reinholm Arttu; Lundberg Rickard; Skön Marika; Österlund Pamela; Melin Merit; Hänninen Arno; Hurme Antti; Ivaska Lauri; Tähtinen Paula A.; Lempainen Johanna; Kakkola Laura; Jalkanen Pinja; Julkunen Ilkka
      <p><b>Introduction</b>: The prime-boost COVID-19 mRNA vaccination strategy has proven to be effective against severe COVID-19 disease and death. However, concerns have been raised due to decreasing neutralizing antibody ...

    • Altered Glucagon Response to Oral Glucose in Individuals at Different Stages of Type 1 Diabetes Development 

      Kontola, Helena; Crisóstomo, Luís; Löyttyniemi, Eliisa; Koskenniemi, Jaakko J.; Veijola, Riitta; Toppari, Jorma; Kero, Jukka
      <p><b>Context</b></p><p>Autoimmune destruction of beta cells and their functional decline precedes the clinical onset of type 1 diabetes. However, altered alpha-cell function and hyperglucagonemia may contribute to the ...

    • Gingival keratinocyte adhesion on atomic layer-deposited hydroxyapatite coated titanium 

      Abushahba, Faleh; Riivari, Sini; Areid, Nagat; Närvä, Elisa; Kylmäoja, Elina; Ritala, Mikko; Tuukkanen, Juha; Vallittu, Pekka K.; Närhi, Timo O.
      <p>This study aimed to evaluate the effects of the atomic layer deposited hydroxyapatite (ALD-HA) coating of the titanium (Ti) surface on human gingival keratinocyte (HGK) cell adhesion, spreading, viability, and hemidesmosome ...

    • General-Purpose Deep Learning Detection and Segmentation Models for Images from a Lidar-Based Camera Sensor 

      Yu Xianjia; Salimpour Sahar; Peña Queralta Jorge; Westerlund Tomi
      Over the last decade, robotic perception algorithms have significantly benefited from the rapid advances in deep learning (DL). Indeed, a significant amount of the autonomy stack of different commercial and research platforms ...

    • Leaky Democracy : Third Parties in Voting Advice Applications 

      Heino, Timi; Rauti, Sampsa; Laato, Samuli; Carlsson, Robin; Leppänen, Ville
      An important part of democracy is the premise of ballot secrecy, where each individual can vote privately without interference, and without anyone getting to say what they vote for. Legislation such as GDPR also indicates ...

    • Cerebral Hemodynamic Impairment and Cognitive Dysfunction in APOE4 Carriers With Asymptomatic Carotid Artery Stenosis/Occlusion 

      Kakino, Yoshinori; Hattori, Yorito; Ogata, Soshiro; Nakaoku, Yuriko; Nishimura, Kunihiro; Iida, Hidehiro; Ihara, Masafumi
      <p><strong>Background </strong><br></p><p>Our previous preclinical study demonstrated that APOE4-targeted replacement mice exhibit more severe cerebral hypoperfusion and cognitive impairment than APOE3-targeted replacement ...

    • Cumulative risk factors for injuries and poisoning requiring hospital care in youth with prenatal substance exposure: A longitudinal controlled cohort study 

      Koponen Anne M.; Gissler Mika; Nissinen Niina-Maria; Autti-Rämö Ilona; Kahila Hanna; Sarkola Taisto
      <p><strong>Aim:</strong> To investigate whether the youth with prenatal substance exposure (PSE) (aged 15-24 years, <em>n</em> = 615) had been in hospital care more often due to injuries and poisoning in comparison with ...

    • Gaze Behavior and Cognitive Performance on Tasks of Multiple Object Tracking and Multiple Identity Tracking by Handball Players and Non-Athletes 

      Styrkowiec Piotr; Cryz Stanisla; Hyönä Jukka; Li Jie; Oksama Lauri; Ras Maciej
      <p>Multiple object tracking (MOT) and multiple identity tracking (MIT) each measure the ability to track moving objects visually. While prior investigators have mainly compared athletes and non-athletes on MOT, MIT more ...

    • Does accelerometer-measured physical activity and sedentary time differ between manual, in-office, hybrid and remote workers? 

      Leskinen, Tuija; Suorsa, Kristin; Pasanen, Jesse; Rovio, Suvi; Niinikoski, Harri; Heinonen, Olli; Pulkki-Råback, Laura; Viikari, Jorma; Rönnemaa, Tapani; Raitakari, Olli T; Stenholm, Sari; Pahkala, Katja
      <div><p><strong>Objectives</strong> Studies on accelerometer-measured daily physical activity behaviour, especially among hybrid and remote workers, are scarce. We compared daily occupational and non-occupational physical ...

    • Validation of the Nurses' Skills to Care for Alcohol-Intoxicated Patients in Emergency Department (NSCAIP-ED) instrument 

      Mäkelä Kaisu-Leena; Kylmä Jari; Koivisto Anna-Maija; Hakala Tiina; Koivunen Marita
      <p>Aim: To report the development and validation of the Nurses' Skills to Care for Alcohol-Intoxicated Patients in Emergency Department instrument, shortened NSCAIP-ED. <br></p><p>Methods: A mixed-methods design was used ...

    • Kulturelles Lernen im DaF-Anfangsunterricht 

      Becker, Christine; Maijala, Minna

    • Use of the Phylobone database for the annotation of bone extracellular matrix proteins in reindeer (Rangifer tarandus) 

      Sánchez-Reverté Alba; Fontcuberta-Rigo Margalida; Nakamura Miho; Puigbò Pere
      Bone extracellular matrix (ECM) proteins play a key role in bone formation and regeneration, including structural and regulatory functions. The Phylobone database consists of 255 ECM protein groups from 39 species and can ...

    • Physician global assessment in rheumatoid arthritis—is there any logic? 

      Jäppinen, Katriina; Muilu, Paula; Autio, Reija; Kuusalo, Laura; Sihvonen, Susanna; Sokka-Isler, Tuulikki; Rantalaiho, Vappu

    • Vocational Student Teachers’ Self-Reported Experiences in Creating ePortfolios 

      Anne-Maria Korhonen; Sanna Ruhalahti; Minna Lakkala; Marjaana Veermans
      <p> </p><p>Context: The context of the study is vocational teacher education and the participants are vocational student teachers. They are studying in a blended learning setting as part time students. They represent ...

    • Hyvinvointivaltio ja kielitietoisuus: hyvinvoinnin diskurssit neljän suurimman puolueen eduskuntavaaliohjelmissa 

      Anne-Maria Karjalainen; Milla Luodonpää-Manni; Veronika Laippala
      <p>In this article we study discourses concerning welfare in political texts. The material consists of programs written for parliamentary elections between 1991 and 2015 by the four largest parties in Finland. The frame ...