Selaus oppiaineen mukaan kokoelmassa Pro gradu -tutkielmat ja diplomityöt sekä syventävien opintojen opinnäytetyöt (kokotekstit) Biomedical Imaging
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Applying Transfer Learning in Classification of Ischemia from Myocardial Polar Maps in PET Cardiac Perfusion Imaging
(19.05.2022)Introduction: Ischemia is defined as the restriction of blood flow to a body organ, such as the heart, resulting in a cutback in oxygen supply. Myocardial ischemia is characterized by an imbalance between myocardial oxygen ...avoin -
Association between intrathoracic adipose tissue mass and metabolic parameters
(Turun yliopisto, 30.05.2018)Overweight or obesity, along with type 2 diabetes mellitus, is one of the major causes of cardiovascular morbidity and mortality. In the heart, fat is deposited inside – myocardial triglyceride content, and outside the ...avoin -
BCR signaling and dynamic micropatterns
(02.12.2021)B lymphocytes (B cells) are an important part of the adaptive immune system. Recognition of surface presented antigen, typically on antigen presenting cell (APC), by the B cell receptor (BCR) triggers BCR signaling cascades ...avoin -
Developing quantitative image analysis pipelines for scoring histological panoramic images : Testing Rab24 as a possible biomarker for cancer
(18.05.2021)Biomarkers are highly essential to improve diagnosis, confirm the diseases' development, and monitor the treatment. Biomarker discovery requires analysis of a large quantity of data which is aided by computational tools. ...avoin -
Differentiation of Metabolically Distinct Areas within Head and Neck Region using Dynamic 18F-FDG Positron Emission Tomography Imaging
(Turun yliopisto, 28.01.2014)Positron Emission Tomography (PET) using <sup>18</sup>F-FDG is playing a vital role in the diagnosis and treatment planning of cancer. However, the most widely used radiotracer, <sup>18</sup>F-FDG, is not specific for ...avoin -
Hyperinsulinemic euglycemic clamp in anesthetized rat : A protocol for rat in vivo FDG PET studies
(13.08.2021)Obesity and physical inactivity are major public health issues in the population of the western countries. These conditions increase the risk for the development of insulin resistance and type 2 diabetes mellitus and lead ...avoin -
IMAGE DERIVED INPUT FUNCTION FOR BRAIN [11C]TMSX PET IMAGING
(05.04.2019)Modeling and analysis of positron emission tomography (PET) imaging data requires the critical information of the input function of the radioligand used. In PET imaging of the brain, the ‘gold standard’ for acquiring input ...avoin -
Imaging salmonella at a single cell resolution
(13.07.2022)Salmonella is a rod-shaped bacterium that infects many cells including macrophages in the gastrointestinal tract and causes salmonellosis. Single-cell technologies are being utilised to study the heterogeneity of ...avoin -
INVESTIGATION OF LIGNIN NANOCAPSULES UPTAKE IN PLANTS
(13.09.2021)The interest of the scientific community in nanotechnology has been growing significantly in the last decades, resulting in the development of new nanomaterials and nanoparticles which can find a wide variety of applications, ...avoin -
Keratins as regulators of colonocyte mitochondria and intestinal barrier function
(15.05.2020)Keratins are part of a filamentous structures forming the cytoskeleton. Keratins provide structural support and are involved in several cell processes. Keratins are known to affect mitochondrial function in the liver but ...avoin -
Light-sheet fluorescent microscopy in tardigrade anoxybiosis
(11.08.2022)Tardigrades are invertebrates that are known for their tolerance to extreme conditions. This research focuses on anoxia, the total lack of oxygen, and the adaptation and survival of anoxiainduced experiments. Cryptobiosis ...avoin -
Neural Structures Associated with Music Engagement in Persons with Alzheimer’s Disease
(01.06.2020)Alzheimer’s disease (AD) is the most common cause of dementia and a major public health issue resulting in decreased life expectancy of patients and high societal cost. Medical treatment of AD is palliative in nature as ...avoin -
Optimization of immunofluorescence protocols for detection of biomarkers in colorectal and breast cancer tissues
(Turun yliopisto, 06.06.2016)Cancer remains an undetermined question for modern medicine. Every year millions of people ranging from children to adult die since the modern treatment is unable to meet the challenge. Research must continue in the ...avoin -
Radiosynthesis and biological evaluation of [68Ga]Ga-NOTA-Folate in experimental atherosclerosis and myocardial infarction models.
(12.05.2020)While many folate-receptor (FR) targeting radiotracers have been studied for imaging cancers, there is a need for tracers that target inflammation for diagnostic and monitoring purposes. Two diseases in which inflammation ...avoin -
Role of keratin filaments on beta-cell mitochondrial behaviour and functionality
(15.05.2019)Keratin (K) intermediate filaments (IFs) are IFs of epithelial cell, and one of the most abundant IFs found in the cells, Keratins have various functions including stress protection, cell signaling and protein targeting. ...avoin -
SYNTHESIS OF MESOPOPROUS SILICA NANOPARTICLES USING DROPLET MICROFLUIDICS
(29.07.2020)Introduction: Nanoparticles are small particles within nanoscale levels. Their size goes up to few hundred nanometers, although some sources state that nanoparticles are up to 100nm in diameter. Structure and function can ...avoin -
The functional role of NOTCH and potential NOTCH associated genes in head and neck cancer
(10.05.2022)Notch signaling is actively involved in cell differentiation, proliferation, and apoptosis, and plays a significant role in tumor growth and prognosis of head and neck squamous cell carcinoma (HNSCC). Altered NOTCH expression ...avoin
