Hae

Antisense oligonucleotides (ASOs) leverage the natural catalytic activity of RNases H to target specific RNA sequences for degradation. However, the challenge lies in incorporating chemical modifications into ASOs to enhance ...

Photochromic sodalite, Na8(AlSiO4)6(Cl,S)2, has been a topic of research for almost 100 years, though only recently has a deep understanding of its remarkably fatigueresistant colour change been obtained. Aside from the ...

Positron emission tomography (PET) is an imaging technique that can be used to follow various biological processes, such as receptor function, in a living body. PET utilisesradiopharmaceuticals, tracers containing short-lived ...

During the drug discovery process molecular libraries containing millions of molecules are screened to find a single potential drug with the highest potency and efficacy over unwanted side-effects. The whole drug development ...

This thesis focused on the proanthocyanidins (PAs), a class of plant specialized metabolites that have a wide range of industrial applications. They play a vital role in the production of various food and feed products. ...

Interest in natural products as pharmaceutical leads has recently resurfaced due to increasing understanding towards the biosynthesis of natural compounds as well as advancements in methodologies that facilitate the ...

Guanosine-5'-triphosphate (GTP) is an essential molecule for cell survival and function. Although free GTP plays a crucial role in several cellular processes, most studies focus solely on the protein bound GTP and its ...

Redox-active metal organic complexes with ‘non-innocent’ ligands are promising candidates when it comes to developing novel homogenous catalysts. The related complexes have gained interest since they could be utilized as ...

The limitations such as toxicity, brittleness, scarcity, and high cost of currently available materials for energy storage and transparent electrode applications in bendable electronics create a need for green, sustainable, ...

The growing environmental crisis has strengthened interest in conversion technologies within the chemical industry, particularly in the reducing of greenhouse gases and minimizing toxic chemicals. To combat these issues, ...