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Spondylolysis is the most common cause of low back pain in adolescents, explaining up to 47% of low back pain in young athletes. It is a stress fracture in one or both of the pars interarticularis of the vertebra, most ...

The prostate-specific antigen (PSA) is the main biomarker for diagnosis and treatment response monitoring in prostate cancer (PCa). In the first part of this thesis, we investigated the prognostic value of ultrasensitive ...

Whole-gland prostate surgery and radiotherapy, the established approaches to localised prostate cancer (PCa), usually cause substantial adverse effects. Targeted image-guided cancer therapy has gained acceptance through ...

The incidence of acute diverticulitis – common disease in Western countries – is increasing worldwide. Acute diverticulitis can be divided by its degree of severity into uncomplicated and complicated forms. Accurate diagnosis ...

Peripheral artery disease (PAD) causes increased all-cause and cardiovascular (CV) mortality. These increases have been associated with abnormal ankle-brachial indices and the extent of atherosclerotic lesions as measured ...

Endovascular aortic treatment involving all aortic segments has replaced open surgery in most patients during the last three decades. Although the endovascular techniques have significantly decreased invasiveness, preoperative ...

Acute appendicitis is the most common reason for acute abdominal pain, currently known to present in two different forms: uncomplicated and complicated acute appendicitis. This difference in appendicitis severity between ...

Surgical repair for ascending aorta regarding an aneurysm or an acute type A aortic dissection (ATAAD) share similar principals in techniques. ATAAD is highly lethal, and the appropriate extent of surgery at acute setting ...