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Genome Mining Actinobacteria: Eliciting the Production of Natural Products
(Turun yliopisto, 2023-06-16)
Antimicrobial resistance is an imminent threat that is expected to kill 10 million people per year by 2050. Natural products have been a major source of antimicrobial compounds and encompass a chemical space far greater ...
Translocation mechanism of the multisubunit RNA polymerase
(Turun yliopisto, 2018-06-08)
The expression and replication of genetic information forms the basis of life. The first step of gene expression, the transcription of DNA into RNA, is carried out in all organisms by multisubunit RNA polymerase enzymes ...
Molecular Mechanisms and Interactions in Regulation of Photosynthetic Reactions
(Turun yliopistoAnnales Universitatis Turkuensis A I 493, 2014-10-24)
In photosynthesis, light energy is converted to chemical energy, which is consumed for carbon assimilation in the Calvin-Benson-Bassham (CBB) cycle. Intensive research has significantly advanced the understanding of how ...
Characterization of cytokine binding and its implications in the physiology of Aggregatibacter actinomycetemcomitans
(Turun yliopisto, 2019-06-07)
Bacterial pathogens cause severe infections in humans. The emergence of multiresistant bacteria requires the development of new antimicrobial strategies. Bacteria utilize various virulence mechanisms to promote their ...