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Seasonal variation in the brain μ-opioid receptor availability
<p>Seasonal rhythms influence emotion and sociability. The brain μ-opioid receptor (MOR) system modulates a multitude of seasonally varying socioemotional functions, but its seasonal variation remains elusive with no ...
Progressive dopaminergic defect in a patient with primary progressive multiple sclerosis
<p>Dopamine has a modulatory role in a number of autoimmune diseases, but there are no published cases of longitudinal dopaminergic imaging in multiple sclerosis (MS). Here we report a patient with primary progressive ...
No Link Between Striatal Dopaminergic Axons and Dopamine Transporter Imagingin Parkinson’s Disease
<p>Background:Brain dopamine transporter binding hasbeen considered a possible biomarker for nigrostriataldegeneration in PD.Objective:To investigate whether dopamine trans-porter binding is associated with the number of ...
Gastrointestinal Symptoms and Dopamine Transporter Asymmetry in Early Parkinson's Disease
<p><strong>Background: </strong>The neurophysiological correlates of gastrointestinal symptoms (GISs) in Parkinson's disease (PD) are not well understood. It has been proposed that in patients with a gastrointestinal origin ...
Depression and Nigral Neuron Density in Lewy Body Spectrum Diseases
Parkinson's disease and other Lewy body spectrum diseases (LBDs) are associated with a specific risk for clinical depression. In the present clinicopathological study with 73 patients with LBD, we observed that the substantia ...
Sex correction improves the accuracy of clinical dopamine transporter imaging
<p>Background <br></p><p>In clinical diagnostic imaging, dopamine transporter (DAT) SPECT scans are commonly evaluated using automated semiquantitative analysis software. Age correction is routinely implemented, but usually ...
Dopamine transporter binding in symptomatic controls and healthy volunteers: Considerations for neuroimaging trials
<p>Objective</p><p>To evaluate possible differences between brain dopamine transporter (DAT) binding in a group of symptomatic parkinsonism patients without dopaminergic degeneration and healthy individuals.</p><p>Backgr ...
Height and nigral neuron density in Parkinson's disease
<p><strong>Background: </strong>The dopaminergic system modulates growth hormone secretion and previous results have suggested a link between short stature and an increased risk of Parkinson's disease (PD).</p><p><strong ...